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Helen Gika
Lecturer, School of Medicine
Personal Information
2310996224
gkikae@auth.gr
http://users.auth.gr/gkikae/
Scopus ID
6506780883
Google Scholar ID
https://scholar.google.gr/citations?hl=en&user=rUsrSNUAAAAJ&view_op=list_works&sortby=pubdate
Γνωστικό Αντικείμενο
:
Ενόργανη Ανάλυση Οργανικών Βιομορίων
Επιστημονική Ειδίκευση
:
Επιστήμη ζωής
Χημεία
Education
Προπτυχιακές Σπουδές
1999
Χημείας
Χημείας
Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
Greece
Διδακτορικό Δίπλωμα
2004
ΔΔ
Χημείας
Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης
Greece
Αναλυτική Χημεία
Course Work
Courses of Spring semester of 2016–17 academic year
ΤΜΗΜΑ ΙΑΤΡΙΚΗΣ
IA0383
Forensic Medicine - Toxicology
ΠΡΟΓΡΑΜΜΑ ΜΕΤΑΠΤΥΧΙΑΚΩΝ ΣΠΟΥΔΩΝ "ΚΛΙΝΙΚΗ ΚΑΙ ΒΙΟΜΗΧΑΝΙΚΗ ΦΑΡΜΑΚΟΛΟΓΙΑ"
ΜΙΦΒ0007
Clinical Toxicology - Instrumental Chemical Analysis
ΜΙΦΒ0008
Pharmacogenomics and other "-omics" - Research and Clinical Applications
Theses Supervised
Student Theses within AUTh
2014–2015
. Aντικαρκινική δράση σικονίνης. Ιn-vitro μελέτη σε ηπατικά κύτταρα και εξέταση του μεταβολικού τους αποτυπώματος.
2012–2013
. Προσδιορισμός των οσμηρών συστατικών σε ρίζες και εκχυλίσματα του φυτού Alkanna tinctoria
Administrative Work
Τμήματος
#
Από
Έως
Θέση Όργανο / Επιτροπή
2
2012
2015
Member, Επιτροπη Ορ. Προγραμματος και εξετασεων
3
2012
2015
Member, Επιτροπη φοιτητικων θεματων
1
2011
2012
Member, Επιτροπή Σεμιναρίων, Εκδόσεων και Δημοσίων Σχέσεων Τμήματος Υποεπιτροπή Εκδόσεων
Research Projects
2014–2015
Προτυποποίηση Αναλυτικών μεθόδων Μεταβονομικής
2012–2013
ΔΡΑΣΗ Α:Ενίσχυση νέων ερευνητικών στη βαθμίδα του Λέκτορα: Μεταβολική μελέτη της αντικαρκινικής δράσης των δραστικών ενώσεων του εκχυλίσματος ρίζας του φυτού Alkanatinctoria και lithospermum erythrorhizon
Συμμετοχές σε συντακτικές επιτροπές περιοδικών
Συμμετοχές σε συντακτικές επιτροπές περιοδικών
2012
Journal of Intergrated OMICS
.
2182-0287
.
Spain
Editorial Board member
Other language
Συμμετοχές σε συντακτικές επιτροπές περιοδικών
Συμμετοχή σε επιτροπή επιστημονικού συνεδρίου
2012-11-09
Workshop on Holistic Analytical Technologies for BioMedical, Food and Plant Sciences
.
Aristotel University of Thess. and University of Athens
.
Greece
Μέλος Οργανωτικής Επιτροπής
.
Ξενόγλωσσο
.
Προσκλήσεις για Διαλέξεις
Σε συνέδρια
2007-12-12
Sampling strategy, TOOLS AND METHODS FOR MASS SPECTROMETRY
.
METABOLOMICS IN NUTRITION
.
NUGO, INRA Clermont-Ferrand
.
France
Σε Πανεπιστήμια και άλλους φορείς
2009-07-15
Validation in LC-MS based metabolomics
.
IASMA-FEM
.
Italy
Συμμετοχές σε συντακτικές επιτροπές περιοδικών
Θέση σε ακαδημαϊκό/ερευνητικό οργανισμό ή επιστημονική εταιρεία
Ιδρυτικό μέλος
.
Ελληνική Εταιρία Φασματομετρίας Μάζας
.
Greece
Publications
2016
Begou O
,
Kontou A
,
Raikos Nikolaos
,
Sarafidis Kosmas
,
Roilides Emmanuel
,
Papadogiannis Ioannis
,
Gika Helen
(2016)
.
An ultra-high pressure liquid chromatography-tandem mass spectrometry method for the quantification of teicoplanin in plasma of neonates
.
Journal of Chromatography B
.
Assimopoulou Andreana
,
Papageorgiou Vasileios
,
Gika Helen
,
Mosialos Georgios
,
Spyrelli E.D
,
Virgiliou C
,
Koletti A
(2016)
.
Metabolic profiling study of shikonin’s inhibitory effect on cancer cell lines
.
9th Joint Natural Products Conference
.
Copenhagen, - Denmark
.
Assimopoulou Andreana
,
Papageorgiou Vasileios
,
Nakas A
,
Gika Helen
,
Taitzoglou Ioannis
,
Poutahidis Theofilos
,
Theodoridis Georgios
(2016)
.
NMR Metabolomics-based study of DSS induced colitis in rats and effect of shikonin
.
4th Workshop on Holistic Analytical Methods for Systems Biology Studies, 17-19 April 2016
.
Thessaloniki, Greece
.
Assimopoulou Andreana
,
Papageorgiou Vasileios
,
Gika Helen
,
Mosialos Georgios
(2016)
.
LC-MS/MS metabolic profiling study of shikonin’s cytotoxocity on Huh-7 cell line
.
4th Workshop on Holistic Analytical Methods for Systems Biology Studies
.
Thessaloniki, Greece
.
2015
Arapitsas Panagiotis
,
Corte Anna Della
,
Gika Helen
,
Narduzzi Luca
,
Mattivi Fulvio
,
Theodoridis Georgios
(2015)
.
Studying the effect of storage conditions on the metabolite content of red wine using HILIC LC–MS based metabolomics
.
Food Chemistry
.
Balkatzopoulou P
,
Fasoula S
,
Gika Helen
,
Nikitas Panagiotis
,
Pappa-Louizi Adriani
(2015)
.
Retention prediction of highly polar ionizable solutes under gradient conditions on a mixed-mode reversed-phase and weak anion-exchange stationary phase
.
Journal of Chromatography A
.
vol.1396 no.C p.72-76
.
Deda Olga
,
Gika Helen
,
Wilson Ian D
,
Theodoridis Georgios
(2015)
.
An overview of fecal sample preparation for global metabolic profiling
.
Journal of Pharmaceutical and Biomedical Analysis
.
Fasoula S
,
Zisi Ch
,
Gika Helen
,
Pappa-Louizi Adriani
,
Nikitas Panagiotis
(2015)
.
Retention prediction and separation optimization under multilinear gradient elution in liquid chromatography with Microsoft Excel macros
.
Journal of Chromatography A
.
vol.1395 no.C p.109-115
.
Fasoula S
,
Zisi Ch
,
Sampsonidis I
,
Virgiliou Ch
,
Theodoridis Georgios
,
Gika Helen
,
Nikitas Panagiotis
,
Pappa-Louizi Adriani
(2015)
.
Multivariate analysis of chromatographic retention data as a supplementary means for grouping structurally related compounds
.
Journal of Chromatography A
.
vol.1387 no.C p.49-52
.
Michopoulos Filippos
,
Gika Helen
,
Palachanis Dimitrios
,
Theodoridis Georgios
,
Wilson Ian
(2015)
.
Solid phase extraction methodology for UPLC-MS based metabolic profiling of urine samples
.
Electrophoresis
.
p.n/a-n/a
.
Sampsonidis Ioannis
,
Witting Michael
,
Koch Wendelin
,
Virgiliou Christina
,
Gika Helen
,
Schmitt-Kopplin Philippe
,
Theodoridis Georgios
(2015)
.
Computational analysis and ratiometric comparison approaches aimed to assist column selection in HILIC-MS/MS targeted metabolomics
.
Journal of Chromatography A
.
Virgiliou Christina
,
Sampsonidis Ioannis
,
Gika Helen
,
Raikos Nikolaos
,
Theodoridis Georgios
(2015)
.
Development and validation of a HILIC-MS/MS multitargeted method for metabolomics applications
.
ELECTROPHORESIS
.
vol.36 no.18 p.2215-2225
.
Gika Helen
,
Kaklamanos George
,
Manesiotis Panagiotis
,
Theodoridis Georgios
(2015)
.
Chromatography- High Performance Liquid Chromatography
.
Encyclopedia of Food and Health
.
Επιμέλεια:Benjamin Caballero, Paul M. Finglas, Fidel Toldra
.
2014
Christou Chrysoula
,
Gika Helen
,
Raikos Nikolaos
,
Theodoridis Georgios
(2014)
.
GC-MS analysis of organic acids in human urine in clinical settings: A study of derivatization and other analytical parameters
.
Journal of Chromatography B
.
vol.964 no.C p.195-201
.
Gika Helen
,
Wilson Ian D
(2014)
.
Global metabolic profiling for the study of alcohol-related disorders
.
Bioanalysis
.
vol.6 no.1 p.59-77
.
Gika Helen
,
Theodoridis Georgios
,
Plumb Robert S
,
Wilson Ian D
(2014)
.
Current practice of liquid chromatography–mass spectrometry in metabolomics and metabonomics
.
Journal of Pharmaceutical and Biomedical Analysis
.
vol.87 no.C p.12-25
.
Gika Helen
,
Wilson Ian D
,
Theodoridis Georgios
(2014)
.
LC–MS-based holistic metabolic profiling. Problems, limitations, advantages, and future perspectives
.
Journal of Chromatography B
.
vol.966 no.C p.1-6
.
Gika Helen
,
Wilson Ian D
,
Theodoridis Georgios
(2014)
.
The Role of Mass Spectrometry in Nontargeted Metabolomics
.
Fundamentals of Advanced Omics Technologies: From Genes to Metabolites
.
Elsevier
.
vol.63 p.213-233
.
Theodoridis Georgios
,
Gika Helen
,
Wilson Ian D
(2014)
.
Analytical methodology for clinical metabolic profiling: sample preparation, sample analysis and statistical evaluation
.
lobal Metabolic Profiling: Clinical Applications
.
Ian D Wilson - Georgios Theodoridis - Andrew Nicholls
.
Theodoridis Georgios
,
Gkika Eleni
,
Nicholls Andrew
,
Wilson Ian D
(2014)
.
Considerations in the design of clinical and epidemiological metabolic phenotyping studies
.
Global Metabolic Profiling: Clinical Applications
.
Επιμέλεια:Edited by Ian D Wilson, Georgios Theodoridis & Andrew Nicholls
.
Koletti Antigoni E
,
Gika Helen
,
Papageorgiou VP
,
Asimopoulou Andreana
(2014)
.
Stability study of the pharmaceutical substance shikonin
.
62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research
.
62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research - GA2014
.
Guimaraes. - Portugal
.
vol.80
.
Kyriazou Α
,
Virgiliou C
,
Spyrelli E.D
,
Mosialos Georgios
,
Papageorgiou VP
,
Asimopoulou Andreana
,
Gika Helen
(2014)
.
Metabolite profiling study of shikonin’s cytotoxic activity in human Huh7 cancer cells
.
Workshop 20th IMSC
.
Workshop 20th IMSC, International Mass Spectrometry Conference
.
Geneva - Switzerland
.
2012
Gika Helen
,
Ji Cheng
,
Theodoridis Georgios
,
Michopoulos Filippos
,
Kaplowitz Neil
,
Wilson Ian D
(2012)
.
Investigation of chronic alcohol consumption in rodents via ultra-high-performance liquid chromatography–mass spectrometry based metabolite profiling
.
Journal of Chromatography A
.
vol.1259 no.C p.128-137
.
Gika Helen
,
Theodoridis Georgios
,
Vrhovsek Urska
,
Mattivi Fulvio
(2012)
.
Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatography–tandem mass spectrometry
.
Journal of Chromatography A
.
vol.1259 no.C p.121-127
.
Gika Helen
,
Theodoridis Georgios
,
Earll Mark
,
Wilson Ian D
(2012)
.
A QC approach to the determination of day-to-day reproducibility and robustness of LC–MS methods for global metabolite profiling in metabonomics/metabolomics
.
Bioanalysis
.
vol.4 no.18 p.2239-2247
.
Gika Helen
,
Theodoridis Georgios
,
Mattivi F
,
Vrhovsek U
,
Pappa-Louizi Adriani
(2012)
.
Retention prediction of a set of amino acids under gradient elution conditions in hydrophilic interaction liquid chromatography
.
Journal of Separation Science
.
vol.35 no.3 p.376-383
.
Gika Helen
,
Theodoridis Georgios
,
Mattivi F
,
Vrhovsek U
,
Pappa-Louizi Adriani
(2012)
.
Hydrophilic interaction ultra performance liquid chromatography retention prediction under gradient elution
.
Analytical and Bioanalytical Chemistry
.
vol.404 no.3 p.701-709
.
Theodoridis Georgios
,
Gika Helen
,
Want E. J
,
Wilson I. D
(2012)
.
Liquid chromatography-mass spectrometry based global metabolite profiling: A review
.
Analytica Chimica Acta
.
vol.711 p.7-16
.
Theodoridis Georgios
,
Gika Helen
,
Franceschi P
,
Caputi L
,
Arapitsas P
,
Scholz M
,
Masuero D
,
Wehrens R
,
Vrhovsek U
,
Mattivi F
(2012)
.
LC-MS based global metabolite profiling of grapes: Solvent extraction protocol optimisation
.
Metabolomics
.
vol.8 no.2 p.175-185
.
Gika Helen
,
Theodoridis Georgios
,
Wilson Ian D
(2012)
.
Application of UHPLC-MS to Metabolomic/metabonomic Studies in Man
.
UHPLC in Life Sciences
.
Επιμέλεια:David Guillarme & Jean-Luc Veuthey
.
τευχ.16 p.387-428
.
2011
Aprea E
,
Gika Helen
,
Carlin S
,
Theodoridis Georgios
,
Vrhovsek U
,
Mattivi F
(2011)
.
Metabolite profiling on apple volatile content based on solid phase microextraction and gas-chromatography time of flight mass spectrometry
.
Journal of Chromatography A
.
vol.1218 no.28 p.4517-4524
.
Gika Helen
,
Theodoridis Georgios
(2011)
.
Sample preparation prior to the LC-MS-based metabolomics/metabonomics of blood-derived samples
.
Bioanalysis
.
vol.3 no.14 p.1647-1661
.
Ramautar R
,
Nevedomskaya E
,
Mayboroda O. A
,
Deelder A. M
,
Wilson I. D
,
Gika Helen
,
Theodoridis Georgios
,
Somsen G. W
,
Jong G. J. de
(2011)
.
Metabolic profiling of human urine by CE-MS using a positively charged capillary coating and comparison with UPLC-MS
.
Molecular BioSystems
.
vol.7 no.1 p.194-199
.
Theodoridis Georgios
,
Gika Helen
,
Wilson I. D
(2011)
.
Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies
.
Mass Spectrometry Reviews
.
vol.30 no.5 p.884-906
.
2010
Friswell M. K
,
Gika Helen
,
Stratford I. J
,
Theodoridis Georgios
,
Telfer B
,
Wilson I. D
,
McBain A. J
(2010)
.
Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice
.
PLoS ONE
.
vol.5 no.1
.
Gika Helen
,
Theodoridis Georgios
,
Earll M
,
Snyder R. W
,
Sumner S. J
,
Wilson I. D
(2010)
.
Does the mass spectrometer define the marker? A comparison of global metabolite profiling data generated simultaneously via UPLC-MS on two different mass spectrometers
.
Analytical Chemistry
.
vol.82 no.19 p.8226-8234
.
Gika Helen
,
Michopoulos F
,
Divanis D
,
Metallidis Symeon
,
Nikolaidis Pavlos
,
Theodoridis Georgios
(2010)
.
Daptomycin determination by liquid chromatography-mass spectrometry in peritoneal fluid, blood plasma, and urine of clinical patients receiving peritoneal dialysis treatment
.
Analytical and Bioanalytical Chemistry
.
vol.397 no.6 p.2191-2197
.
Pechlivanis A
,
Kostidis S
,
Saraslanidis Ploutarchos
,
Petridou A
,
Tsalis G
,
Mougios Vasileios
,
Gika Helen
,
Mikros E
,
Theodoridis Georgios
(2010)
.
1H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine
.
Journal of Proteome Research
.
vol.9 no.12 p.6405-6416
.
Spagou K
,
Tsoukali-Papadopoulou Eleni
,
Raikos Nikolaos
,
Gika Helen
,
Wilson I. D
,
Theodoridis Georgios
(2010)
.
Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies
.
Journal of Separation Science
.
vol.33 no.6-7 p.716-727
.
Want E. J
,
Wilson I. D
,
Gika Helen
,
Theodoridis Georgios
,
Plumb R. S
,
Shockcor J
,
Holmes E
,
Nicholson J. K
(2010)
.
Global metabolic profiling procedures for urine using UPLC-MS
.
Nature Protocols
.
vol.5 no.6 p.1005-1018
.
2009
Gika Helen
,
Theodoridou A
,
Michopoulos F
,
Theodoridis Georgios
,
Diza-Mataftsi Evdoxia
,
Settas Loukas
,
Nikolaidis Pavlos
,
Smith C
,
Wilson I. D
(2009)
.
Determination of two COX-2 inhibitors in serum and synovial fluid of patients with inflammatory arthritis by ultra performance liquid chromatography-inductively coupled plasma mass spectroscopy and quadrupole time-of-flight mass spectrometry
.
Journal of Pharmaceutical and Biomedical Analysis
.
vol.49 no.3 p.579-586
.
Lai L
,
Michopoulos F
,
Gika Helen
,
Theodoridis Georgios
,
Wilkinson R. W
,
Odedra R
,
Wingate J
,
Bonner R
,
Tate S
,
Wilson I. D
(2009)
.
Methodological considerations in the development of HPLC-MS methods for the analysis of rodent plasma for metabonomic studies
.
Molecular BioSystems
.
vol.6 no.1 p.108-120
.
Michopoulos F
,
Lai L
,
Gika Helen
,
Theodoridis Georgios
,
Wilson I
(2009)
.
UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction
.
Journal of Proteome Research
.
vol.8 no.4 p.2114-2121
.
Plumb Robert S
,
Rainville Paul D
,
Potts Warren B
,
Johnson Kelly A
,
Gika Helen
,
Wilson Ian D
(2009)
.
Application of Ultra Performance Liquid Chromatography−Mass Spectrometry to Profiling Rat and Dog Bile
.
Journal of Proteome Research
.
vol.8 no.5 p.2495-2500
.
Raikos Nikolaos
,
Theodoridis Georgios
,
Alexiadou E
,
Gika Helen
,
Argyriadou Eleni
,
Parlapani Eleni
,
Tsoukali-Papadopoulou Eleni
(2009)
.
Analysis of anaesthetics and analgesics in human urine by headspace SPME and GC
.
Journal of Separation Science
.
vol.32 no.7 p.1018-1026
.
2008
Gika Helen
,
Theodoridis Georgios
,
Wilson I. D
(2008)
.
Liquid chromatography and ultra-performance liquid chromatography-mass spectrometry fingerprinting of human urine. Sample stability under different handling and storage conditions for metabonomics studies
.
Journal of Chromatography A
.
vol.1189 no.1-2 p.314-322
.
Gika Helen
,
Theodoridis Georgios
,
Wilson I. D
(2008)
.
Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine
.
Journal of Separation Science
.
vol.31 no.9 p.1598-1608
.
Gika Helen
,
Theodoridis Georgios
,
Extance J
,
Edge A. M
,
Wilson I. D
(2008)
.
High temperature-ultra performance liquid chromatography-mass spectrometry for the metabonomic analysis of Zucker rat urine
.
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
.
vol.871 no.2 p.279-287
.
Gika Helen
,
Macpherson E
,
Theodoridis Georgios
,
Wilson I. D
(2008)
.
Evaluation of the repeatability of ultra-performance liquid chromatography-TOF-MS for global metabolic profiling of human urine samples
.
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
.
vol.871 no.2 p.299-305
.
Loftus N
,
Miseki K
,
Iida J
,
Gika Helen
,
Theodoridis Georgios
,
Wilson I. D
(2008)
.
Profiling and biomarker identification in plasma from different Zucker rat strains via high mass accuracy multistage mass spectrometric analysis using liquid chromatography/mass spectrometry with a quadrupole ion trap-time of flight mass spectrometer
.
Rapid Communications in Mass Spectrometry
.
vol.22 no.16 p.2547-2554
.
Theodoridis Georgios
,
Gika Helen
,
Wilson I. D
(2008)
.
LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
.
TrAC - Trends in Analytical Chemistry
.
vol.27 no.3 p.251-260
.
2007
Gika Helen
,
Theodoridis Georgios
,
Wingate J. E
,
Wilson I. D
(2007)
.
Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: Application to human urine
.
Journal of Proteome Research
.
vol.6 no.8 p.3291-3303
.
2005
Papadogiannis Ioannis
,
Gika Helen
(2005)
.
Peak Purity Determination with a Diode Array Detector
.
Journal of Liquid chromatography & Related Technologies
.
Published Version
.
vol.27 no.6 p.1083 - 1092
.
Papadogiannis Ioannis
,
Samanidou Viktoria
,
Gika Helen
(2005)
.
Development of a validated HPLC method for the determination of iodotyrosines and iodothyronines in pharmaceuticals and biological samples using solid phase extraction
.
Journal of Chromatography B
.
Published Version
.
vol.814 no.1 p.163-172
.
Papadogiannis Ioannis
,
Gika Helen
(2005)
.
Peak Purity Determination with a Diode Array Detector (chapter 254)
.
Encyclopedia of Chromatography, Second Edition
.
p. 1198-1202
.
2004
Gika Helen
,
Lammerhofer M
,
Papadogiannis Ioannis
,
Lindner W
(2004)
.
Direct separation and quantitative analysis of thyroxine and triiodothyronine enantiomers in pharmaceuticals by high-performance liquid chromatography
.
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
.
vol.800 no.1-2 p.193-201
.
Papadogiannis Ioannis
,
Gika Helen
(2004)
.
Peak Identification with a Diode Array Detector
.
Encyclopedia of Chromatography 2004 Update Supplement
.
Επιμέλεια:Jack Cazes
.
p.1192-1197
.
2000
Samanidou V. F
,
Gika Helen
,
Papadogiannis Ioannis
(2000)
.
Rapid HPLC analysis of thyroid gland hormones tri-iodothyronine (T3) and thyroxine (T4) in human biological fluids after SPE
.
Journal of Liquid Chromatography and Related Technologies
.
vol.23 no.5 p.681-692
.
2013
Theodoridis Georgios
,
Gika Helen
,
Plumb Robert
,
Wilson Ian D
(2013)
.
Liquid Chromatographic Methods Combined with Mass Spectrometry in Metabolomics (chapter 9)
.
Proteomic and Metabolomic Approaches to Biomarker Discovery
.
Elsevier
.
p.145–161
.
Theodoridis Georgios
,
Gika Helen
,
Wilson Ian D
(2013)
.
LC-MS-Based Nontargeted Metabolomics
.
Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data
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Aktualisiert: 2017-07-11