Course Information
TitleΒιοτεχνολογία / Biotechnology
SchoolChemical Engineering
Cycle / Level1st / Undergraduate
Teaching PeriodWinter
Course ID20002619

Programme of Study: PPS Tmīmatos CΗīmikṓn Mīchanikṓn (2021-sīmera)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
KORMOSCompulsory Course535

Class Information
Academic Year2016 – 2017
Class PeriodWinter
Faculty Instructors
Weekly Hours4
Total Hours52
Class ID
Course Type 2016-2020
  • Background
Course Type 2011-2015
General Foundation
Mode of Delivery
  • Face to face
Digital Course Content
The course is also offered to exchange programme students.
Language of Instruction
  • Greek (Instruction, Examination)
  • English (Instruction, Examination)
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Adapt to new situations
  • Make decisions
  • Work autonomously
  • Work in an interdisciplinary team
  • Generate new research ideas
  • Design and manage projects
  • Respect natural environment
  • Advance free, creative and causative thinking
Course Content (Syllabus)
Historical overview. Cell: Procaryotic and eukaryotic cells. Morphology. Chemical components of cells. Microorganisms. Important cell types. Cell cultures (animal, plant and microbial). Kinetics of cell growth-Equations. Methods for determination of cell growth. Enzymes. Kinetics of enzyme-catalyzed reactions. Michaelis-Menten equation. Briggs-Haldone kinetics. Evaluations of parameters in the Michaelis-Menten equation. Effect of pH and tempwrature on Enzyme kinetics. Order of enzyme-catalyzed reaction. Inhibition. Reversible inhibition. Competitive and non competitive inhibition. Immobilized enzymes and applications: Methods for immobilization. Examples. Applications of immobilized enzymes in industry. Production of L-amino acids with immobilized. a-amino acylase, β-galactosidase for hydrolysis of lactose, semi synthetic penicillins. Commercial immobilized enzymes. Sterilization: Methods of sterilization. Heat, chemical reagents, mechanical methods, ultrasound. Sterilization by heating. Continuous and non continuous sterilization. Bioreactors: Types of bioreactors. Productivity and designing of bioreactors. Factors influencing the operation of a bioreactor. Bioseparations-Dowbstream processing: General. Broth handling Seperation of liquid-solid. Filtration, Centrifugation. Cell lysis (Chemical, Enzymic and Physical methods). Product recaovery: Extraction. Adsorption. Product purification: Precipitation, Electrophoresis, Chromatography ion exchange, affinity and gell permeation chromatography). Ultrafiltration. Biotechnological applications. Synthesis and modification of polymers. Proteins and polypeptides Oligo- and polysaccharides. Degradation of starch by enzymes. Single cell proteins. Biosensors of proteins.
Microorganisms, Immobilized enzymes, Bioseparations-Dowbstream processing, Biotechnological applications
Educational Material Types
  • Notes
  • Book
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Communication with Students
Course Organization
Student Assessment
Student Assessment methods
  • Written Assignment (Formative, Summative)
  • Oral Exams (Formative, Summative)
  • Written Exam with Problem Solving (Formative, Summative)
Course Bibliography (Eudoxus)
1. Μ. Λιακοπούλου-Κυριακίδου, 'Βιοτεχνολογία με στοιχεία Βιοχημικής Μηχανικής', Εκδόσεις Ζήτη
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