Biorganic Chemistry and New Products
| Title | Βιοργανική Χημεία και Νέα Προϊόντα / Biorganic Chemistry and New Products |
| Code | KT061 |
| Faculty | Engineering |
| School | Chemical Engineering |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Common | No |
| Status | Active |
| Course ID | 20000750 |
Programme of Study: PPS Tmīmatos CΗīmikṓn Mīchanikṓn (2021-sīmera)
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Elective Courses | Spring | - | 5 |
| Academic Year | 2016 – 2017 |
| Class Period | Spring |
| Instructors from Other Categories | |
| Weekly Hours | 3 |
| Class ID | 600056530
|
Class Schedule
| Building | Πολυτεχνείο (πτέρυγα Β) |
| Floor | Όροφος 2 |
| Hall | ΑΙΘΟΥΣΑ 1 (41) |
| Calendar | Τρίτη 16:00 έως 19:00 |
Course Type 2016-2020
- Scientific Area
- Skills Development
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600056530
Erasmus
The course is also offered to exchange programme students.
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Adapt to new situations
- Make decisions
- Work autonomously
- Work in an international context
- Work in an interdisciplinary team
- Design and manage projects
- Advance free, creative and causative thinking
Course Content (Syllabus)
Introduction. Chemistry of Amino acids, peptides and proteins. Geometry of peptide bond, coupling of amino acids-methods of peptide synthesis. Protection of amino, carboxyl and of other functional groups of amino acids.
Solid phase and solution synthesis of peptides. Protein conformation, physicochemical properties of proteins. Denaturation. Methods for purification, isolation and identification of proteins. Classification of proteins. Enzymes: General Catalysts: Homogeneous and heterogeneous catalysis, enzymes, Enzyme specifications, nomenclature, coenzymes. Hydrolytic Enzymes-applications. Non-hydrolytic enzymes and their applications. Kinetics of Enzyme reactions –equations. Effect of pH and temperature. Enzyme Inhibitors: multiple substrates – Competitive and non competitive inhibition. Equations-Examples.
Enzyme immobilization: methods of immobilization (molecular and ion bonding, adsorption, entrapment, copolymerization)
Enzyme models: general – Host and guest theory. Ion-phores, Polymers and Cyclodextrins.
Enzyme production from animal, plant, cells and microorganisms. Biotransformation, microbial production of chemicals, vitamins, sugars, steroids, antibiotics.
Chemistry of Nucleic Acids: structure, (primary and secondary conformation). DNA denaturation. Nucleosides and nucleotides. Nomenclature and symbols. Chemical reactions of nucleic acids. Chemical synthesis of oligo- and polynucleotides. Some well known nucleotides and their biological role. DNA and RNA replication. Genetic code. Protein biosynthesis.
Chemical modification of proteins. New syntheses. Solid state reactions. Solvent free reactions. Products with applications to Biomedicine and Pharmaceutics.
Keywords
Enzymes, Proteins, Solid state reactions, Solvent free reactions, New synthesis
Educational Material Types
- Notes
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Communication with Students
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | |||||
| Tutorial | |||||
| Total |
Student Assessment
Student Assessment methods
- Written Assignment (Formative, Summative)
- Oral Exams (Formative, Summative)
Bibliography
Course Bibliography (Eudoxus)
1. Μ. Λιακοπούλου-Κυριακίδου, "Βιοργανική Χημεία", Εκδόσεις Ζήτη, 2004
Last Update
22-01-2014
