BIOINFORMATICS
| Title | ΒΙΟΠΛΗΡΟΦΟΡΙΚΗ (Ε) / BIOINFORMATICS |
| Code | ΝΠ47 |
| Faculty | Health Sciences |
| School | Pharmacy |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Common | Yes |
| Status | Active |
| Course ID | 180000288 |
| Academic Year | 2016 – 2017 |
| Class Period | Spring |
| Instructors from Other Categories | |
| Weekly Hours | 2 |
| Total Hours | 26 |
| Class ID | 600067206
|
Class Schedule
| Building | Φυσικομαθηματική (Δ) |
| Floor | Υπόγειο 1 |
| Hall | ΑΙΘΟΥΣΑ Δ12 (184) |
| Calendar | Παρασκευή 16:00 έως 17:00 |
Course Type 2016-2020
- Scientific Area
- Skills Development
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600067206
- At the Website of the School: http://www.pharm.auth.gr/el/node/119
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
Prerequisites
Required Courses
- 84 MOLECULAR BIOLOGY
- ΝΠ-04 COMPUTING-INTERNET
- ΝΠ-06 ENGLISH LANGUAGE A (1/4)
- ΝΠ-11 ENGLISH LANGUAGE B (2/4)
- ΝΠ-16 ENGLISH LANGUAGE C (3/4)
- ΝΠ-21 ENGLISH LANGUAGE D (4/4)
Learning Outcomes
Familiarization with the application of informatics on the organization and understanding of biological information. Training on the use and analysis of molecular data for biological inference. Acquisition of technical skills on the use of several biological databases available in the internet. Familiarization with online tools for retrieval, comparison and analysis of biological data. Training on the use of various software and online servers for homology establishment, sequence and genome analysis, determination of 3D macromolecular structure. Theoretical background on evolutionary models.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Work autonomously
- Work in teams
- Work in an international context
- Work in an interdisciplinary team
- Generate new research ideas
Course Content (Syllabus)
Lectures: Molecular markers and types of molecular data. Definition, design and structure of biological databases. Search strategies. Analysis and evaluation of search results. Protein structure prediction. Analysis of motifs. Determination of 3D structure. Sequence alignment and establishment of homology. Models of molecular evolution. Pharmacogenomics. Molecular fingerprinting. Future bioinformatics and developments in computational biology.
Keywords
Bioinformatics, Biological databases, Alignment, Pharmacogenomics
Educational Material Types
- Slide presentations
- Interactive excersises
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
- Use of ICT in Student Assessment
Description
Power Point presentations, use of computer room and electronic communication with the students.
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | ✓ | ||||
| Seminars | ✓ | ||||
| Tutorial | ✓ | ||||
| Interactive Teaching in Information Center | ✓ | ||||
| Total |
Student Assessment
Description
Written exams. Evaluation through multiple choice tests and questions on knowledge/reasoning.
Student Assessment methods
- Written Exam with Multiple Choice Questions (Summative)
- Written Exam with Short Answer Questions (Summative)
- Written Exam with Extended Answer Questions (Summative)
- Written Assignment (Summative)
- Written Exam with Problem Solving (Summative)
Bibliography
Course Bibliography (Eudoxus)
Baxevanis A.D. & Ouellette F. (Ελληνική έκδοση). 2004. Βιοπληροφορική. Επιστημονικές Εκδόσεις Παρισιάνου Α.Ε. Αθήνα (Επιμέλεια ελληνικής έκδοσης: Ευάγγελος Ν. Μουδριανάκης, Σταύρος Ι. Χαμόδρακας).
Additional bibliography for study
β1. Ηλεκτρονικό υλικό στο Blackboard
β2. Χρήσιμες ιστοσελίδες
- National Center for Biotechnology Information (NCBI)
http://www.ncbi.nlm.nih.gov/
- European Bioinformatics Institute (EBI)
http://www.ebi.ac.uk/
- Ensembl Genome Browser
http://www.ensembl.org/index.html
- PubMed
http://www.ncbi.nlm.nih.gov/pubmed
- Bionformatics (Oxford Journals)
http://bioinformatics.oxfordjournals.org/
- Nucleic Acids Research (Oxford Journals)
http://nar.oxfordjournals.org/
- Sequence Retrieval System (SRS)
http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-page+srsq2+-noSession
- Codon Usage Database
http://www.kazusa.or.jp/codon/
- The Restriction Enzyme Database (REBASE)
http://rebase.neb.com/rebase/rebase.html
- Genomatix Software Suite
http://www.genomatix.de/cgi-bin/tools/tools.pl
- Bioweb (Institut Pasteur)
http://bioweb2.pasteur.fr/
- The GENSCAN Web Server at MIT
http://genes.mit.edu/GENSCAN.html
- Softberry
http://linux1.softberry.com/berry.phtml
- Phylogeny Programs
http://evolution.genetics.washington.edu/phylip/software.html
Last Update
08-11-2015
