Structural Biochemistry and Basics of Biocomputational Chemistry
| Title | ΔΟΜΙΚΗ ΒΙΟΧΗΜΕΙΑ ΚΑΙ ΣΤΟΙΧΕΙΑ ΒΙΟΠΛΗΡΟΦΟΡΙΚΗΣ / Structural Biochemistry and Basics of Biocomputational Chemistry |
| Code | Κ309 |
| Faculty | Sciences |
| School | Chemistry |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Common | Yes |
| Status | Active |
| Course ID | 40002697 |
Programme of Study: PPS-Tmīma CΗīmeías (2016-sīmera)
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| THEŌRĪTIKĪ CΗĪMEIA KAI CΗĪMIKĪ EKPAIDEUSĪ | Optional Courses | 8 | 4 | 5 |
| CΗĪMIKĪ ANALYSĪ-PERIVALLON-ĪLEKTROCΗĪMEIA | Optional Courses | 8 | 4 | 5 |
| CΗĪMIKĪ SYNTHESĪ-VIOCΗĪMEIA KAI VIOEFARMOGES | Elective Course belonging to the selected specialization (Elective Specialization Course) | 8 | 4 | 5 |
| CΗĪMIKĪ TECΗNOLOGIA KAI VIOMĪCΗANIKĪ CΗĪMEIA | Optional Courses | 8 | 4 | 5 |
| Academic Year | 2017 – 2018 |
| Class Period | Spring |
| Faculty Instructors |
|
| Weekly Hours | 3 |
| Class ID | 600101710
|
Class Schedule
| Building | Χημείας (Παλαιό Α) |
| Floor | Όροφος 4 |
| Hall | ΝΗΣΙΔΑ ΑΡΙΣΤΟΤΕΛΗ (453) |
| Calendar | Τρίτη 10:00 έως 13:00 |
Course Type 2016-2020
- Scientific Area
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600101710
- At the Website of the School: http://www.chem.auth.gr/bioinfo/
Language of Instruction
- Greek (Instruction)
- English (Instruction)
Prerequisites
Required Courses
- Υ15 Biochemistry I
- Υ17 Biochemistry II
Learning Outcomes
Knowledge acquisition regarding searching on scientific Data banks related to proteins and nucleic acids.
A deeper study ,based on new technologies, of macromolecular structure (examples of relation to diseases)
Introduction to basic tools of bioinformatic .
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Adapt to new situations
- Work in teams
- Work in an international context
- Work in an interdisciplinary team
Course Content (Syllabus)
STRUCTURAL BIOCHEMISTRY
Basic structural principles, the building blocks, motifs of protein structures, a-domain structures, alpha/beta structures, beta structures, protein folding, DNA structures, helix-turn-helix, DNA recognition by proteins with the helix-turn-helix motif. Structural motifs of eukaryotic transcription factors , structures of serine proteases, structures of membrane proteins, structures of fibrous proteins, recognition of foreign molecules by the immune system, prediction engineering and design of protein structures, determination of protein structures.
INTRODUCTION TO BIOINFORMATICS
Data base indexing and specification of search terms. Structural bioinformatics. Introduction to sequence alignments, sequence similarity, FASTA, BLAST,multiple alignment, CLUSTALW, MOTIFS, Phylogenetic trees, prediction of secondary structure of proteins and nucleic acids,. Navigation to proteomic and protein engineering tools. Design of primers for PCR. Structural alignment of protein structure.
Keywords
structural Biochemistry, structure function relation ship
Educational Material Types
- Slide presentations
- Video lectures
- Multimedia
- Interactive excersises
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
Description
Video , power point, book
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 26 | 1.0 | ✓ | ||
| Total | 26 | 1.0 |
Student Assessment
Student Assessment methods
- Written Assignment (Formative)
Bibliography
Course Bibliography (Eudoxus)
Εισαγωγή στη δομή των πρωτεϊνών( Carl Branden and John Tooze), μεταφραση
Βιοπληροφορική (Σοφία Κοσσιδα)
Additional bibliography for study
Bioinformatic ( Sofia Kossida)
Introduction to Protein Structure (Carl Branden and John Tooze),translation
Last Update
20-09-2013
