The students are expected to
• gain knowledge, critical thinking and technical skills in the specific field, based on and stemming from their general undergraduate level education in courses including primarily materials, inorganic chemistry, polymer chemistry, biology and genetics. This achievable goal is supported by advanced scientific textbooks and laboratory manuals (along with electronic aids) yet relies on established views emerging from contemporary developments in cutting edge technology of their interdisciplinary field of specialization.
• be in a position to put the acquired knowledge and expertise to work in ways reflecting professional approaches and conduct in their work environment. They are also expected to have acquired skills commensurate with their knowledge, attested to through development and presentation of articulate arguments directly linked to case problem resolution in their field of interest and specialization.
• have the ability to analyze, synthesize and interpret relevant data (essentially adapting to their own field of specialization), thereby formulating views and opinions pertaining to resolution of intimately linked social, scientific and ethical issues.
• be in a position to report, publicize, and announce new information, promote ideas and put forward potential solutions to novel problems akin to expert, targeted and non-specialized common public-audience(s).
• develop skills of knowledge acquisition, assimilation and processing needed for further delving into their studies with a greater degree of autonomy and independence.
Course Content (Syllabus)
Course contents cover the following units
1. Introduction to materials
a) General properties
b) Surfaces in functional biological materials
c) Role of water in biomaterials
2. Families of biomaterials (natural products, metals, alloys, polymers, hydrogels, hybrid materials, etc.)
3. Cellular exploration, biochemistry and biomedicine
a) Biomolecules in intracellular and extracellular fluids
b) Tissues and cell-biomaterial interactions
4. Degradation of materials in a biological milieu
5. Applications of materials in medicine (artificial organs)
6. Tissue engineering (immuno-isolation, synthetic scaffolds, etc.)
7. Biomaterials in action (implants, biodevices, etc.)
8. Biomedicinal nanotechnology
Development of laboratory activities related intimately to the production and isolation of biological materials (e.g. DNA, RNA) and bioinformatics technology linked to novel biomaterials research.
The class covers two main activities:
1. The theoretical part referring the aforementioned contents
2. The experimental part extending to two Laboratory periods during which famialiarization will be pursued with
a) the production of biological genetic material, and
b) bioinformatics search of a diverse class of materials (proteins, enzymes, RNA, DNA, etc.)
in relevance to biomaterials development.
The goals of the specific class include:
1. Understanding of the fundamental principles of materials science and engineering involved in natural and synthetic biomaterials and (bio)material products of engineering processes.
2. Applications in biology, biotechnology and biomedical technology, with specific examples involving quantification
3. Structure and properties of biomaterials
4. Mechanical properties, toxicity and biocompatibility of biomaterials
5. Methods of biomaterials production
Biomaterials, biological engineering, biomedicinal applications, testing, design and synthesis of biomaterials, cell-biomaterials interactions
Course Bibliography (Eudoxus)
-Προτεινόμενη Βιβλιογραφία :
1. Βiomaterials Science
An Introduction to
Materials in Medicine
Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons. Elsevier Acad. Press, 2004.
2. Fundamentals of Materials Science and Engineering
William D. Callister, Jr.
John Wiley & Sons, Inc., 2001
3. Principles of Biomedical Engineering
Sundararajan V. Madihally
Artech House, Boston 2010
4. Biomaterials. Principles and Applications
Joon B. Park, J. D. Bronzino
CRC Press, 2003