Biomaterials
| Title | Βιοϋλικά / Biomaterials |
| Code | KY043 |
| Faculty | Engineering |
| School | Chemical Engineering |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Common | No |
| Status | Active |
| Course ID | 20002632 |
Programme of Study: PPS Tmīmatos CΗīmikṓn Mīchanikṓn (2021-sīmera)
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Elective Courses | Spring | - | 5 |
| Academic Year | 2018 – 2019 |
| Class Period | Winter |
| Faculty Instructors |
|
| Weekly Hours | 3 |
| Class ID | 600125436
|
Course Type 2016-2020
- Background
- General Knowledge
- Scientific Area
- Skills Development
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600125436
- At the Website of the School: http://www.cheng.auth.gr/jm/
- eLearning (Moodle): https://elearning.auth.gr/
- Other: http://bioinorglab.web.auth.gr/gr_site/
Erasmus
The course is also offered to exchange programme students.
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
Prerequisites
General Prerequisites
The course intends to introduce chemical engineering students to contemporary biotechnology with emphasis on biomaterials. Tha latter family of materials constitutes a significant part of research and technology at the international level. The class targets the comprehension of basic principles of the science of materials and engineering processes involved in synthetic materials and material products of engineering processes.
Learning Outcomes
Through the course, students are expected to
• acquire current knowledge of basic concepts, principles and applications of modern science (bio)materials in chemical and biomedical engineering, getting accustomed to using scientific vocabulary and simple language.
• learn how proteins and cells can interact with various biomaterials, and be involved in host responses to implants, including toxicity and health effects.
• familiarize themselves with basic synthetic and fabrication strategies related to the creation of new biomaterials.
• develop their personal experimental skills in basic knowledge of advanced (bio)materials chemistry (3D printing of scaffolds and tissues)
• gain knowledge of basic characteristics of qualitative chemical experimental research in modern chemistry of (bio)materials and critically understand its role in chemical engineering and modern applications in hybrid technological (bio)materials.
• accrue basic skills on applications of modern biomechanical and genetic technology
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Work autonomously
- Work in teams
- Work in an interdisciplinary team
- Appreciate diversity and multiculturality
- Respect natural environment
- Be critical and self-critical
- Advance free, creative and causative thinking
Course Content (Syllabus)
Course contents cover the following units
1. Introduction to materials
a) General properties
b) Surfaces in functional biological materials
c) Role of water in biomaterials
2. Families of biomaterials (natural products, metals, alloys, polymers, hydrogels, hybrid materials, etc.)
3. Cellular exploration, biochemistry and biomedicine
4. Degradation of materials in a biological milieu
5. Applications of materials in medicine (artificial organs)
6. Tissue engineering (immuno-isolation, synthetic scaffolds, etc.)
7. Biomaterials in action (implants, biodevices, etc.)
Development of laboratory activities related intimately to biotechnology (e.g. staining) and bioinformatics technology linked to novel biomaterials research.
The class covers two main activities:
1. The theoretical part referring the aforementioned contents
2. The experimental part extending to two Laboratory periods during which famialiarization will be pursued with
a) the production of biological genetic material, and
b) bioinformatics search of a diverse class of materials (proteins, enzymes, RNA, DNA, etc.)
in relevance to biomaterials development.
Keywords
(bio)materials, biotechnology, applications in modern medicine, interactions between hybrid materials and cellular surfaces
Educational Material Types
- Slide presentations
- Video lectures
- Multimedia
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
Description
During class recitations the following Information Technology and Communications means are employed: 1. Personal PCs and University Servers 2. Scientific videos
For student communication the following media are employed: 1. E-mail 2.Phone communication 3. Skype
During Lab Experimental Sessions the following media are employed: 1. Personal PCs and University Servers 2. Scientific videos 3.Internet searches
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 39 | ✓ | |||
| Laboratory Work | 26 | ✓ | ✓ | ||
| Reading Assigment | 24 | ✓ | |||
| Tutorial | 24 | ✓ | |||
| Interactive Teaching in Information Center | 6 | ✓ | |||
| Written assigments | 28 | ✓ | |||
| Exams | 3 | ✓ | |||
| Total | 150 |
Student Assessment
Description
The fundamental criteria for student performance evaluation are listed in the following Web Site:
http://bioinorglab.web.auth.gr/gr_site/Labs/
Student Assessment methods
- Written Exam with Short Answer Questions (Formative, Summative)
- Written Exam with Problem Solving (Formative, Summative)
- Labortatory Assignment (Formative, Summative)
- Homework sets (Formative, Summative)
Bibliography
Course Bibliography (Eudoxus)
Προτεινόμενα Βιβλία
1. Biomaterials Science
An Introduction to Materials in Medicine, 2nd Edition
B. D. Ratner, A. S. Hoffman, F. J. Schoen, J. E. Lemons
Elsevier Academic Press, 2004
2. Genetic Engineering – A primer
Walter E. Hill
Taylor & Francis, 2002
3. Biomaterials
J. Y Wong, J. D. Bronzino
CRC Press, Taylor & Francis, 2007
4. Fundamentals of Materials Science and Engineering
William D. Callister, Jr.
John Wiley & Sons, Inc., 2001
5. Bioinformatics
A Practical Guide to the Analysis of Genes and Proteins
A. D. Baxevanis, B.F.F. Ouellette
Wiley Interscience, 2001
6. Advanced Data Mining Technologies in Bioinformatics
H.-H. Hsu
Idea Group Publishing, 2006
7. Bioinformatics Algorithms
Techniques and Applications
I. I. Mǎndoiu, A. Zelikovsky
John Wiley & Sons, Inc., 2001
Additional bibliography for study
Περιοδικά που συνιστώνται να παρακολουθούνται στην βιβλιοθήκη και την ηλεκτρονική βάση Heal Link
1. Advanced Materials
2. Annual Review of Materials Research
3. Journal of Biological Chemistry
4. Journal of Experimental Medicine
5. Journal of Control Release
6. Cell
7. Cellular and Molecular Immunology
8. Nature Reviews in Immunology
9. Immunology
10. Nature Biology
11. Nature Medicine
12. Proceedings of the National Academy of Science, U.S.A.
13. Nature Biotechnology
14. Science
15. Journal of the American Medical Associations (JAMA)
16. Biomaterials
17. Biomacromolecules
18. Trends in Biological Sciences
19. Journal of Biomedical Materials Research
20. Advances in Polymer Science
21. European Polymer Journal
22. Journal of Applied Polymer Science
23. Nature Reviews in Drug Discovery
24. Advanced Drug Delivery Reviews
25. Clinical Investigations
Last Update
22-05-2020
