Comparative Physiology of Laboratory Animals

Course Information
TitleΣΥΓΚΡΙΤΙΚΗ ΦΥΣΙΟΛΟΓΙΑ ΤΩΝ ΖΩΩΝ ΕΡΓΑΣΤΗΡΙΟΥ / Comparative Physiology of Laboratory Animals
FacultyHealth Sciences
Cycle / Level1st / Undergraduate
Teaching PeriodSpring
CoordinatorIoannis Zervos
Course ID600014604

Programme of Study: PPS Tmīmatos Ktīniatrikīs (2020-2021)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
KORMOSElective Courses632

Class Information
Academic Year2018 – 2019
Class PeriodSpring
Faculty Instructors
Weekly Hours16
Class ID
Course Type 2016-2020
  • General Knowledge
  • Scientific Area
  • Skills Development
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
  • Face to face
Digital Course Content
The course is also offered to exchange programme students.
Language of Instruction
  • Greek (Instruction, Examination)
Required Courses
  • 3.2.0 Physiology III
  • 1.3 General Histology-Embryology Theory
  • 2.1.0 Anatomy-Histology II Theory
  • 1.4 Anatomy-Histology I
  • 2.2.0 Physiology II
  • 1.4..1 Anatomy-Histology I Practise
  • 1.4 Anatomy-Histology I Theory
  • 1.5 Physiology I
  • 2.1..1 Anatomy-Histology II Practical
  • 2.1 Anatomy-Histology II
  • 3.1 Anatomy-Histology III Theory
  • 3.1.01 Anatomy-Histology III Praactise
  • 3.1 Anatomy-Histology III
Learning Outcomes
After completing the course, the student should be able to: - Identify and describe the national and European legislation which regulate the scientific use of animals - Demonstrate a comprehensive understanding of the principle of the 3Rs, list examples of how the 3Rs can be implemented in research projects - Describe the severity classification system - Describe the principle of implementing early humane endpoints and how this implementation can influence animal health and welfare during the course of an experiment - Describe the basic biology of the relevant animal species, including physiology, reproduction and behavior - Describe the environmental factors of importance for maintaining an appropriate health status for the animals - Describe the principles of humane killing and list appropriate euthanasia methods for the relevant animal species - Recognize that the choice of a euthanasia method may influence the scientific outcome - Describe appropriate methods and principles for handling animals, and describe common techniques / procedures, including administration and sampling techniques - Describe the variables affecting significance, including the meaning of statistical power and the "p-value" - Indicate some of the problems associated with pain recognition and pain management in animals
General Competences
  • Apply knowledge in practice
  • Adapt to new situations
  • Make decisions
  • Work autonomously
  • Work in an interdisciplinary team
  • Generate new research ideas
  • Design and manage projects
  • Respect natural environment
  • Advance free, creative and causative thinking
Course Content (Syllabus)
1st-2nd hour Introduction. Laboratory animal species. The use of laboratory animals in biomedical research. Legislation for the well-being of animals during experimental protocols. Historical background. Future perspectives. 3rd-4th hour Physiology of the reproductive system. Management of animal reproduction in the facility. 5th-6th hour Physiology of the digestive system. Nutritional requirements. Physiopathology of digestive disorders. 7th-8th hour Physiology of the endocrine system. Physiology of the circulatory system, the blood and haemopoietic tissues. Physiology of the immune system. 9th-10thhour Laboratory animal facilities. Cages and Housing. Physiopathology of management and housing-related diseases. Stress, pain, behavior. Memory and learning. Animal welfare. 11th-12th hour Experimental protocol design, applications of experimental protocols in accordance with species characteristics and the experimentation prerequisites. Animal handling and biological material sampling. Safety. Practical Training 4 hours Laboratory animal handling
Laboratory animals, biomedical research, physiology
Educational Material Types
  • Notes
  • Slide presentations
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Laboratory Teaching
  • Use of ICT in Communication with Students
Course Organization
Laboratory Work4
Written assigments7
Additional bibliography for study
-The handbook of experimental animals: The Laboratory Rat, Academic Press, 2000, editor Georg J Krinke -The Experimetal Animal in Bimedical Research (Volumes I, II) CRC Press, 1995, editors Rollin E Bernard, Kesel Lynne M -Fundamentals of Laboratory Animal Science: CRC press 2017, Enqui Liu and Jianglin Fan (eds).
Last Update