Comparative Physiology of Laboratory Animals
| Title | ΣΥΓΚΡΙΤΙΚΗ ΦΥΣΙΟΛΟΓΙΑ ΤΩΝ ΖΩΩΝ ΕΡΓΑΣΤΗΡΙΟΥ / Comparative Physiology of Laboratory Animals |
| Code | 6.14 |
| Faculty | Health Sciences |
| School | Veterinary |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Coordinator | Ioannis Taitzoglou |
| Common | Yes |
| Status | Active |
| Course ID | 600014604 |
Programme of Study: PPS Tmīmatos Ktīniatrikīs (2020-2021)
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Elective Courses | 6 | 3 | 2 |
| Academic Year | 2018 – 2019 |
| Class Period | Spring |
| Faculty Instructors | |
| Weekly Hours | 16 |
| Class ID | 600131341
|
Course Type 2016-2020
- General Knowledge
- Scientific Area
- Skills Development
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600131341
Erasmus
The course is also offered to exchange programme students.
Language of Instruction
- Greek (Instruction, Examination)
Prerequisites
Required Courses
- 3.2.0 Physiology III
- 1.3 General Histology-Embryology Theory
- 2.1.0 Anatomy-Histology II Theory
- 1.4 Anatomy-Histology I
- 2.2.0 Physiology II
- 1.4..1 Anatomy-Histology I Practise
- 1.4 Anatomy-Histology I Theory
- 1.5 Physiology I
- 2.1..1 Anatomy-Histology II Practical
- 2.1 Anatomy-Histology II
- 3.1 Anatomy-Histology III Theory
- 3.1.01 Anatomy-Histology III Praactise
- 3.1 Anatomy-Histology III
Learning Outcomes
After completing the course, the student should be able to:
- Identify and describe the national and European legislation which regulate the scientific use of animals
- Demonstrate a comprehensive understanding of the principle of the 3Rs, list examples of how the 3Rs can be implemented in research projects
- Describe the severity classification system
- Describe the principle of implementing early humane endpoints and how this implementation can influence animal health and welfare during the course of an experiment
- Describe the basic biology of the relevant animal species, including physiology, reproduction and behavior
- Describe the environmental factors of importance for maintaining an appropriate health status for the animals
- Describe the principles of humane killing and list appropriate euthanasia methods for the relevant animal species
- Recognize that the choice of a euthanasia method may influence the scientific outcome
- Describe appropriate methods and principles for handling animals, and describe common techniques / procedures, including administration and sampling techniques
- Describe the variables affecting significance, including the meaning of statistical power and the "p-value"
- Indicate some of the problems associated with pain recognition and pain management in animals
General Competences
- Apply knowledge in practice
- Adapt to new situations
- Make decisions
- Work autonomously
- Work in an interdisciplinary team
- Generate new research ideas
- Design and manage projects
- Respect natural environment
- Advance free, creative and causative thinking
Course Content (Syllabus)
1st-2nd hour Introduction. Laboratory animal species. The use of laboratory animals in biomedical research. Legislation for the well-being of animals during experimental protocols. Historical background. Future perspectives.
3rd-4th hour Physiology of the reproductive system. Management of animal reproduction in the facility.
5th-6th hour Physiology of the digestive system. Nutritional requirements. Physiopathology of digestive disorders.
7th-8th hour Physiology of the endocrine system. Physiology of the circulatory system, the blood and haemopoietic tissues. Physiology of the immune system.
9th-10thhour Laboratory animal facilities. Cages and Housing. Physiopathology of management and housing-related diseases. Stress, pain, behavior. Memory and learning. Animal welfare.
11th-12th hour Experimental protocol design, applications of experimental protocols in accordance with species characteristics and the experimentation prerequisites. Animal handling and biological material sampling. Safety.
Practical Training
4 hours Laboratory animal handling
Keywords
Laboratory animals, biomedical research, physiology
Educational Material Types
- Notes
- Slide presentations
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 36 | ✓ | |||
| Laboratory Work | 4 | ✓ | |||
| Written assigments | 7 | ✓ | |||
| Exams | 3 | ✓ | |||
| Total | 50 |
Bibliography
Additional bibliography for study
-The handbook of experimental animals: The Laboratory Rat, Academic Press, 2000, editor Georg J Krinke
-The Experimetal Animal in Bimedical Research (Volumes I, II) CRC Press, 1995, editors Rollin E Bernard, Kesel Lynne M
-Fundamentals of Laboratory Animal Science: CRC press 2017, Enqui Liu and Jianglin Fan (eds).
Last Update
28-06-2018
