Learning Outcomes
To introduce students into the basic principles of Pharmacology; the pharmacodynamics and pharmacokinetics parameters of drugs; the various pharmacological classes of drugs; the mechanism underlying the actions of the drugs in the body; the factors contributing to pharmacological response; the emergence of adverse drug reactions (ADRs); drug interactions; drug dosage scheme selection upon drug prescription and drug delivery in clinical practice.
Course Content (Syllabus)
Introduction to Pharmacology; Drug-receptor interactions; Mechanisms underlying the emergence of drug resistance; Pharmacogenetics-Pharmacogenomics and drug idiosyncrasy; Pharmacokinetics processes: absorption, distribution, metabolism, excretion (ADME); Drug interactions; Neuron cell types; Synapses; Taxonomy of neuronal receptors; Mechanism of action and structure-activity relationships of neurotransmitters; Autonomous nervous system; Parasympathomimetic drugs acting either in muscarinic or nicotinic receptors; Acetyl-cholinesterase-inhibiting drugs; Parasympatholytic drugs; Autonomic ganglia-blocking drugs; Skeletal muscle relaxant drugs; Sympathomimetics acting on adrenergic alpha- or beta- receptors; Sympatholytics acting on adrenergic alpha- or beta- receptors; Cardiac glycosides and positive inotropic agents; Diuretic drugs; Antihypertensive and anti-angina agents; Antiarrhythmic agents; Histamine and antihistaminics; Ergot alkaloids; Bronchodilators and other agents used for the treatment of asthma; Local anaesthetics; Drugs acting in gastrointestinal tract and the liver-bile duct system; Anti-hypercholesterolemia drugs; Hormones of hypothalamus and pituitary gland (hypophysis); Thyroid hormones and related drugs; Adrenal glands hormones and related agents; Estrogens; Androgens; Diabetes, Insulin and related drugs; Vitamins.