INORGANIC PHARMACEUTICAL CHEMISTRY
| Title | ΑΝΟΡΓΑΝΗ ΦΑΡΜΑΚΕΥΤΙΚΗ ΧΗΜΕΙΑ / INORGANIC PHARMACEUTICAL CHEMISTRY |
| Code | 20 |
| Faculty | Health Sciences |
| School | Pharmacy |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Winter |
| Common | No |
| Status | Active |
| Course ID | 180000105 |
| Academic Year | 2018 – 2019 |
| Class Period | Winter |
| Faculty Instructors | |
| Weekly Hours | 4 |
| Class ID | 600131533
|
Class Schedule
| Building | Σχ. Θετικών Επιστημών - νέο κτίριο - Ανατολ. πτέρυγα |
| Floor | Υπόγειο 1 |
| Hall | ΑΙΘΟΥΣΑ Δ12 (184) |
| Calendar | Wednesday 11:00 to 12:00 |
| Building | Σχ. Θετικών Επιστημών - νέο κτίριο - Ανατολ. πτέρυγα |
| Floor | Υπόγειο 1 |
| Hall | ΑΙΘΟΥΣΑ Δ12 (184) |
| Calendar | Monday 13:00 to 14:00 |
Course Type 2016-2020
- Scientific Area
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600131533
- At the Website of the School: http://www.pharm.auth.gr
Erasmus
The course is also offered to exchange programme students.
Language of Instruction
- Greek (Instruction, Examination)
Learning Outcomes
Aims of the course: Understanding by students the meaning of inorganic drug, including its chemical properties and its biological role as well as of elements (metals and metalloids) involved in its structure and synthesis. Aims comprise knowledge and skill (capacity) of synthesis, quality control, characterization, quantity control of pharmaceutical preparations which contain inorganic drugs , their mechanism of action at the molecular level as well as their use and side effects.
Scills: Familiarity with basic meanings such as: a) biological activity of metals-metalloids b) biological activity of inorganic compounds of pharmaceutical interest, c) their interaction with biological targets and d) with characterization –quality/quantity control.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Adapt to new situations
- Make decisions
- Work autonomously
- Work in teams
- Work in an international context
- Work in an interdisciplinary team
- Generate new research ideas
- Design and manage projects
- Appreciate diversity and multiculturality
- Respect natural environment
- Demonstrate social, professional and ethical commitment and sensitivity to gender issues
- Be critical and self-critical
- Advance free, creative and causative thinking
Course Content (Syllabus)
Contents of the course:
Inspection of elements in the groups of periodic table in respect with Chemistry-Pharmacological/Toxicological activity, biological activity of metals-metalloids, inorganic compounds of pharmaceutical interest: synthesis/origin , quality/quantity control, properties , uses, side effects and their chemical explanation.
Group Ι
Lithium. Lithium carbonate. Natrium (sodium), natrium carbonicum and bicarbonicum, natrium sulfuricum, natrium thiosulfatum, natrium citricum,natrium tetraboracium, natrium fluoratum, natrium chloratum, natrium phosphoricum bibasicum andbiphosphoricum.
Potassium. Kalium iodatum, kalium permanganicum,potassium chloride.
Group ΙΙ
Αλκαλικές γαίες. Magnesium, magnesium oxydatum, magnesium carbonicum leve, magnesium sulfuricum, magnesium steaticum and trisylicicum, magnesium hydroxidatum , magma magnesiamagnesium chloratum.
Calcium. Calcium phosphoricum dibasicum, calcium phosphate,calcium chloride , calcium glyconicum, calcium sulfuricum, calcium hydroxidatum, calcium hydroxidatum solution, Calccium-Pharmacology.
Barium. Barium sulfuricum .
Group ΙΙΙ
Borium. Acidum boricum.
Aluminium. Aluminium hydroxidatum, colloidale, aluminium hydroxidatum gelatum siccum, alumen.
Group ΙV
Carboneum, carboneum activate.
Silicium. Bentonitum, Kaolinum leve- Bolus-alba laevigata, talcum purificatum.
Pliumbum.
Group V
Nitrogenum. Oxydum nitrosum, ammonia concentrate,ammonium hydricum solutum, ammonium carbonicum,ammonium chloratum.
Arsenicum.Acidum arsenicum. Toxicity of arsenicum’s compounds and their antidotes.
Stibium, Stibio-kalium tartaricum.
Bismuthum.
Group VΙ
Oxygenium. Aqua destilata.Hydrogenium peroxidatum.
Sulfur. Sulfur praecipitatum..
Group VΙΙ
Halogens.Acidum hydrochloricum, cxalcaria chlorata (calcium hypochlorosum.
Iodum. Tinctura iodi.
Magganium as trace element.
Sub-groip ΙΒ
Cuprum. Cuprum sulfuricum. Role of cuprum in organism. Cuprum sulfuricum.
Argentum. Argentum nitricum.Argentum compounds .
Sub-group ΙΙΒ
Zincum.Zincum oxidatum. Zincum as trace element. Consequences of its deficient in organism.. Interaction of zincum with vitamines..
Hydrargirum. Hydrargyrum oxidatum flavum.Hydrargyrum bichloratum.Υδράργυρος. Hydrargirum cyanicum.
Group VΙΙΙ
Ferrum. Ferrum as trace element. Ferrum glyconicum. Ferrum sulfuricum.
Also:
Tungsten, Thallium, Cadmium, Cobalt, Selenium, Vanadium, Nickel, Platinum and compounds in pharmaceutical use as drugs.
Keywords
metals, metalloids, inorganic compounds, drugs,
Educational Material Types
- Notes
- Slide presentations
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Communication with Students
Description
1) A. Geronikaki
Lectures are presented as Powerpoint.
2) Dimitra Hadjipavlou-Litina, professor
Lectures, notes, statements etc are presented in the corresponding place of the website of the School of Pharmacy.
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | ✓ | ✓ | |||
| Laboratory Work | ✓ | ||||
| Total |
Student Assessment
Description
Advance written exams (A ), exams in the end of semester (B).
Examination is based on some questions which should be answered according to the obtained knowledge during semester as well as to ability to combine knowledge with information and their critical thought.
Exams in the end of semester take place on data and hours as well as auditoriums announced by Department.
Duration of exams is 3 h.
Marks are rotatable.
Α) Advance examination
Right to participate in this examination have students of 3d semester who attend the lectures (among 6 lectures presence in 3 allow the participation in this examination).
There are two examinations, one in the middle of the course and another in the end. Only students who succeed (mark 5 or higher) in the first examination can participate in the second. Students succeeded in this examination are relieved from the examination in the end of semester and total mark is average of two examinations.
During laboratory practice students present the composition of their results. At the end of laboratory practice students have written examination on it. Success in laboratory practice (average of notebook and test should be 5 at least) allow the participation in exams in the end of semester. The laboratory practice mark participate in the final mark by 20%.
Student Assessment methods
- Written Exam with Multiple Choice Questions (Formative)
- Written Exam with Short Answer Questions (Summative)
Bibliography
Course Bibliography (Eudoxus)
Ανόργανη Φαρμακευτική Χημεία Α. Γερονικάκη,Εκδόσεις Σύγχρονη Παιδεία 2008 Θεσσαλονίκη
ISBN 978-960-357-014-1
Additional bibliography for study
1. Remingtons:Pharmaceutical Sciences 14 Ed.Mac.Publishing Co., Easton, 1970.
2. Roger’s Inorganic Pharmaceutical Chemistry, 8th ed., by T.O.Soine and C.O.Wilson, Lea and Felinger, Filadelfia, 1967.
3. Βιο-Ανόργανη Χημεία R.W.Hay, editor Εllis Horwood (Ελληνική απόδοση από τους Ε. Μάνεση-Ζούπα & Δ. Ράπτη). Εκδόσεις Παπαζήση, 1992
4. Bioinorganic Chemistry: Inorganic Elements in the Chemistry and Life. An Introduction and Guide. W. Kaim & B. Schwderski. Editor Wiley, 1994
5. Εθνικό συνταγολόγιο Εκδόσεις Εθνικός Οργανισμός Φαρμάκων 2007
Last Update
09-07-2014
