SPECIFIC TOPICS OF ADVANCED MEDICINAL CHEMISTRY

Course Information
TitleΕΙΔΙΚΑ ΘΕΜΑΤΑ ΠΡΟΧΩΡΗΜΕΝΗΣ ΦΑΡΜΑΚΟΧΗΜΕΙΑΣ / SPECIFIC TOPICS OF ADVANCED MEDICINAL CHEMISTRY
CodeΑΦ0005
FacultyHealth Sciences
SchoolPharmacy
Cycle / Level2nd / Postgraduate, 3rd / Doctorate
Teaching PeriodWinter/Spring
CommonNo
StatusActive
Course ID180000004

Programme of Study: PPS of School of Pharmacy (2014-)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
Μedicinal Chemistry, Development of Pharmaceutical CompoundsCompulsory Course2110

Programme of Study: PPS of School of Pharmacy (2012-today)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
Μedicinal Chemistry, Development of Pharmaceutical CompoundsCompulsory Course2110

Class Information
Academic Year2018 – 2019
Class PeriodWinter
Faculty Instructors
Weekly Hours3
Class ID
600133189
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
The outcome of this course is the study of structure and reactions between drug molecules and macromolecular structures of the organism, because this leads not only to the elucidation of the chemical basis of activity for a bioactive compound, but it constitutes the safest way for the discovery of effective drug molecules. The nature of these bonds and the concept of drug-receptor interactions are presented. Another outcome is the knowledge of cannabinoids and their receptors, an important and recent discovery. Approaches for the discovery of cannabinoid receptor agonists and antagonists, as well as possible applications in conditions like pain, cardiovascular disorders, cachexia due to AIDS, appetite control, effect on the immune system are presented. From an educational viewpoint, cannabinoid receptors are an example of G-protein coupled receptors. The analysis and comprehension of this triple system of signal transduction as a means for drug design are a further outcome. Upon completion of this course, the student will learn how to design targeted radiopharmaceuticals specific for the detection or radiotherapy of various diseases.
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Work autonomously
  • Be critical and self-critical
  • Advance free, creative and causative thinking
Course Content (Syllabus)
This course deals with the chemical study of structure and reactions between drug molecules and macromolecular structures of the organism, because this leads not only to the elucidation of the chemical basis of activity for a bioactive compound, but it constitutes the safest way for the discovery of effective drug molecules. The nature of these bonds and the concept of drug-receptor interactions are presented. Part of this course deals with cannabinoids and their receptors, an important and recent discovery. Approaches for the discovery of cannabinoid receptor agonists and antagonists, as well as possible applications in conditions like pain, cardiovascular disorders, cachexia due to AIDS, appetite control, effect on the immune system are presented. From an educational viewpoint, cannabinoid receptors are an example of G-protein coupled receptors. The analysis and comprehension of this triple system of signal transduction as a means for drug design are are explained. Principles of design of targeted radiopharmaceuticals. Special topics on tumor imaging and radiotherapy with radiopharmaceuticals: a) targeted for metabolic processes, b) specific for transmembrane receptors (via bioactive peptides) and c) specific for cancer cells via antibody-antigen interactions. Diagnostic radiopharmaceuticals for the detection of neurological disorders (dopaminergic system).
Educational Material Types
  • Notes
  • Slide presentations
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Communication with Students
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures391.3
Total391.3
Student Assessment
Description
Student assessment will be conducted via written exam and via written essays or assignments.
Student Assessment methods
  • Written Exam with Short Answer Questions (Summative)
  • Written Assignment (Summative)
Last Update
10-07-2013