DESIGNING SEMISYNTHETIC MODIFICATIONS

Course Information
TitleΣΤΡΑΤΗΓΙΚΗ ΗΜΙΣΥΝΘΕΤΙΚΩΝ ΤΡΟΠΟΠΟΙΗΣΕΩΝ / DESIGNING SEMISYNTHETIC MODIFICATIONS
CodeΦΦ0009
FacultyHealth Sciences
SchoolPharmacy
Cycle / Level2nd / Postgraduate, 3rd / Doctorate
Teaching PeriodWinter/Spring
CommonNo
StatusActive
Course ID180000032

Class Information
Academic Year2018 – 2019
Class PeriodWinter
Faculty Instructors
Weekly Hours2
Class ID
600133217
Course Type 2016-2020
  • Scientific Area
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
Aims of the course: The objective of the present course is to establish an interactive approach in preparing new chemical entities via the retrosynthetic approach. It is addressing postgraduate Pharmacy students in the teaching cycle of their studies and, therefore, it is prerequisite for their scientific evolvement. Skills: The present course will establish the thesis that the postgraduate Pharmacy should be able to use the central principles of chemistry in order to understand the basic concepts of synthetic strategy. Synthetic strategy is something more than just organic synthesis – it teaches intellectual synthesis as well.
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Adapt to new situations
  • Make decisions
  • Work autonomously
  • Work in teams
  • Work in an international context
  • Work in an interdisciplinary team
  • Generate new research ideas
  • Design and manage projects
  • Appreciate diversity and multiculturality
  • Respect natural environment
  • Demonstrate social, professional and ethical commitment and sensitivity to gender issues
  • Be critical and self-critical
  • Advance free, creative and causative thinking
Course Content (Syllabus)
In this course the students are becoming familiar of the conception of synthon (i.e. structural unit, constitutive of a molecule, which is related to its putative synthetic handling), as a main “tool” for successfully solving synthetic problems through “retrosynthetic strategy” for the preparation of organic molecules of pharmacological interest. The used examples during the course’s lectures are molecules reported in the international pharmaceutical literature.
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Communication with Students
Description
The lectures of the course are based on the classical chalk and a blackboard method with occasional use of slides. There is also the possibility of communication and exchange of tutorials via e-mail.
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures260.9
Reading Assigment130.4
Total391.3
Student Assessment
Description
The evaluation of knowledge and skills which have been acquitted by the students from the course work is attested via written homework involving solution of composite synthetic problems which are conducted in a fixed date. The students are asked to answer based on their knowledge obtained from the lectures as well as on the critical thinking and ability to combine, evaluate and handle the acquired knowledge and information.
Student Assessment methods
  • Written Assignment (Formative)
Bibliography
Additional bibliography for study
Stuart Warren & Paul Wyatt «Organic Synthesis: The Disconnection Approach», 2009, ISBN-13: 978-047071236
Last Update
11-05-2013