GENERAL PHARMACEUTICAL TECHNOLOGY

Course Information
TitleΓΕΝΙΚΗ ΦΑΡΜ/ΚΗ ΤΕΧΝΟΛΟΓΙΑ / GENERAL PHARMACEUTICAL TECHNOLOGY
Code46
FacultyHealth Sciences
SchoolPharmacy
Cycle / Level1st / Undergraduate
Teaching PeriodSpring
CommonNo
StatusActive
Course ID180000085

Programme of Study: Programme of Studies 2008-

Registered students: 245
OrientationAttendance TypeSemesterYearECTS
CoreCompulsory Course426

Class Information
Academic Year2018 – 2019
Class PeriodSpring
Faculty Instructors
Weekly Hours4
Class ID
600137703
Type of the Course
  • Background
  • General Knowledge
  • Scientific Area
  • Skills Development
Course Category
Specific Foundation / Core
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
: Basic knowledge of the design and operation of pharmaceutical units and of the steps of development of dosage forms through to the final product and submission to the Health authorities for Production licence and marketing. The concept and the importance of particle size and particle shape in drug formulation. Understanding of the mechanism of basic pharmaceutical operations including size reduction, mixing, separation processes, filtration, drying and freeze-drying, its importance in drug formulation and practical application on a laboratory scale. The teaching with lecture presentation is enhanced with practical classes using drugs and excipients of pharmaceutical specifications.
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Make decisions
  • Work autonomously
  • Work in teams
  • Advance free, creative and causative thinking
Course Content (Syllabus)
The design and operation of pharmaceutical industry. Development of pharmaceutical dosage forms. Production licence. Basic pharmaceutical operations. Size reduction – Mechanism, material properties, energy considerations, specific cases. Methods and milling equipment. Size distribution of the productand changes during milling. Mechanical separation of particles. Methods, assessment of efficiency. Separation from air with sieving, aerodynamic classification, sedimentation, elutriation. Filtration and factors that affect the filtration rate, mechanisms and filtration means. Mixing of powdered materials – Mechanism of random mixing and interactive mixing. Sampling techniques, size and mixing indices. Factors affecting the mixing process. Types, characteristics and operation of mixers. Drying- Definitions. Measurement of relative humidity. Theory of drying, movement of liquid during drying, mechanism of heat transfer, drying periods, equilibrium moisture and influence of material. Dryers. Freeze drying – Principles of freeze-drying and applications in Pharmacy. The practical classes involve the processes of Particle size analysis by sieving and air permeability, size reduction, mixing and drying. Computers and appropriate software are used for data processing.
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Laboratory Teaching
  • Use of ICT in Communication with Students
Description
The lectures and tuition presentations are delivered using Powerpoint, video presentations etc.)
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures39
Laboratory Work65
Internship
Other / Others
Total104
Student Assessment
Description
Sitting 3h examination at the end of Semester. Evaluation is based on the student response in writing on 5-6 topics plus 1-2 questions/problems from laboratory work. Results are disclosed and shown on notice board of The Department within 1-2 weeks from the examination. Before sitting the exam the student completes a written detailed report on the work conducted in the practical classes
Student Assessment methods
  • Written Exam with Short Answer Questions (Summative)
  • Written Exam with Extended Answer Questions (Summative)
  • Written Assignment (Formative)
Bibliography
Course Bibliography (Eudoxus)
1. ‘Σημειώσεις Γενικής Φαρμακευτικής Τεχνολογίας (Φυσικές Διεργασίες)’ Ι. Νικολακάκης, Υπηρεσία Δημοσιευμάτων Α.Π.Θ., Θεσσαλονίκη 1998 (σελ. 95) - Δακτυλογραφημένες σημειώσεις για τις ανάγκες των φοιτητών οι οποίες περιέχουν τα κεφάλαια: 1. Η Φαρμακευτική Βιομηχανία, 2. Ελάττωση Μεγέθους (Θραύση και άλεση) 3. Μηχανικοί Διαχωρισμοί Τεμαχιδίων, 4. Ανάμιξη Κόνεων (Τυχαίας κίνησης και αλληλεπίδρασης τεμαχιδίων), 5. Ξήρανση, 6. Λυοφιλοποίηση. - Διαφάνειες των παρουσιάσεων του μαθήματος με ύλη επιπλέον των σημειώσεων. Διανέμονται ηλεκτρονικά μέσω του συστήματος Blackboard.
Additional bibliography for study
- I. Nikolakakis Lecture notes on Pharmaceutical Unit Operations (2010). They are aupdated every year and are made available in the internet through the Blackboard.
Last Update
29-04-2013