BIOPHARMACEUTICS

Course Information
TitleΒΙΟΦΑΡΜΑΚΕΥΤΙΚΗ / BIOPHARMACEUTICS
Code51
FacultyHealth Sciences
SchoolPharmacy
Cycle / Level1st / Undergraduate
Teaching PeriodSpring
CommonNo
StatusActive
Course ID180000089

Programme of Study: Programme of Studies 2008-

Registered students: 330
OrientationAttendance TypeSemesterYearECTS
CoreCompulsory Course634

Class Information
Academic Year2018 – 2019
Class PeriodSpring
Faculty Instructors
Weekly Hours4
Class ID
600137707
Type of the Course
  • Background
  • General Knowledge
  • Scientific Area
  • Skills Development
Course Category
Specific Foundation / Core
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
The main objective is the complete presentation of the influence offormulation factors on the therapeutic efficacy and safety of pharmaceutical products. Also, the influence of the roots of administration in combination with the physicochemical characteristics of the drugs, on the efficacy and safety fo the product.
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Make decisions
  • Work autonomously
  • Work in teams
Course Content (Syllabus)
Introductions-Definitions. Pharmacokinetic parameters and absorption, distribution, metabolism and excretion models. Bioavailability and bioequivalence of pharmaceutical products and drug substances. Route of the drug from the dosage form to the gastric fluids (instant and modified dosage forms, mechanisms, equations and ways to study drug release). Movement of dosage forms in the gastro-intestinal tract (anatomy and physiology of GI tract, biologic barriers and mechanisms of transport and absorption of medicines, physiologic and formulation factors that affect the bioavailability of per os administered pharmaceutical products). Routes of drug administration other than per os (oral cavity, skin, intra-muscular injection, rectum, nasal cavity, lungs etc.) The drug after arrival in the systemic circulation (distribution, protein binding and elimination). Excretion and drug metabolism (renal and hepatic clearance, hepatocholic excretion and enterohepatic circulation). First pass metabolism (factors that affect its appearance and consequences for the bioavailability of drugs). Dosage scheme for specific medicines and diseases. Practical classes in pharmacokinetic simulations and calculation of pharmacokinetic parameters using computers and interactive software for self-teaching. Ιn vitro - in vivo correlation of pharmacokinetic behaviour of pharmaceutical products and drugs.
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Laboratory Teaching
  • Use of ICT in Communication with Students
Description
The lectures and tuition presentations are delivered using Powerpoint, video presentations etc.)
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures
Laboratory Work
Reading Assigment
Total
Student Assessment
Description
Three hours writing examination at the end of Semester. Evaluation is based on the student response in providing answers on 6-8 topics. Results are disclosed and shown on notice board of The Department within 1-2 weeks from the examination. Before sitting the exam the student completes a written detailed report on the work conducted in the practical classes
Student Assessment methods
  • Written Exam with Short Answer Questions (Summative)
  • Written Exam with Extended Answer Questions (Summative)
  • Written Assignment (Formative)
  • Oral Exams (Summative)
Bibliography
Additional bibliography for study
1. ‘ΣΗΜΕΙΩΣΕΙΣ ΒΙΟΦΑΡΜΑΚΕΥΤΙΚΗΣ (ΒΙΟΦΑΡΜΑΚΕΥΤΙΚΗ ΣΥΜΠΕΡΙΦΟΡΑ ΚΑΙ ΑΝΑΠΤΥΞΗ ΔΟΣΟΛΟΓΙΚΩΝ ΜΟΡΦΩΝ)' Σ.Χ. ΜΑΛΑΜΑΤΑΡΗΣ, Υπηρεσία Δημοσιευμάτων Α.Π.Θ., Θεσσαλονίκη 2010 2. ‘ΣΗΜΕΙΩΣΕΙΣ ΒΙΟΦΑΡΜΑΚΕΥΤΙΚΗΣ (ΠΟΡΕΙΕΣ ΑΠΟΜΑΚΡΥΝΣΗΣ ΤΟΥ ΦΑΡΜΑΚΟΥ ΑΠΟ ΤΟ ΣΩΜΑ, ΑΛΛΕΣ ΟΔΟΙ ΧΟΡΗΓΗΣΗΣ)' Ι. ΝΙΚΟΛΑΚΑΚΗΣ
Last Update
30-04-2013