Aims of the course: To provide knowledge the higher organisms capacity that through the molecular and cellular elements of the immune system, develop mechanisms recognizing “self” from “non-self” components of the host-organism or the environment and exhibit natural innate or adaptive defense mechanisms leading in their neutralization or their selective tolerance. To familiarize students with the complex host defense mechanisms against external pathogens or infective environmental factors.
Skills: : By the end of this course, the students should be able to recognize the molecular and cellular components of immune system in association with knowledge using antibodies or antigens as basic tools in prevention-protection against pathogens, in diagnosis, in research as well as in the development of immunotechnology.
Course Content (Syllabus)
1. Introduction, basic principles and evolution
2. Organization of the immune system and the lymphatic system
3. Host resistance-Active (vaccines) and passive (serum) immunization
4. Antibody structure and activity, genetic and molecular basis of antibody diversity
5. Immunogens and antigens
6. The complement system
7. Mechanisms of cellular and humoral immune responses (regulation at the cellular and molecular level-immunotolerance)
8. Major histocompatibility complex and transplantations
9. Immunology of cancer - autoimmunity
10. Future and perspectives
immunobiology, lymphatic system, leucocytes, immune responses, immunochemistry