Pharmaceutical Technology I

Course Information
TitleΦαρμακευτική Τεχνολογία Ι / Pharmaceutical Technology I
FacultyHealth Sciences
Cycle / Level1st / Undergraduate
Teaching PeriodWinter
Course ID600013757

Programme of Study: PPS Tmīmatos Farmakeutikīs (2018-)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
KORMOSCompulsory Course536

Class Information
Academic Year2019 – 2020
Class PeriodWinter
Weekly Hours4
Class ID
Course Type 2016-2020
  • Scientific Area
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
The main objective of the course is to understand the concept of particle size and its methods of measurement. Understanding key processes used in the production of pharmaceuticals and pharmaceuticals in general, such as crystallization, grinding, mixing, particle separation and drying including freeze drying. Laboratory practical work and video demonstrations are complementary used aiming to acquaint students with the above unit operations.
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Make decisions
  • Work autonomously
  • Work in teams
  • Advance free, creative and causative thinking
Course Content (Syllabus)
General aspects about pharmaceutical industry. Phases of the development of pharmaceutical dosage forms. Production and marketing license. Fundamental unit operations. Crystallization-Mechanism, methods and devices. Reduction in size - Mechanism, properties of materials that affect, energy vision, special cases. Methods and devices. Size of particles obtained and changes during milling. Mechanical particle separations - Methods, Estimation of Efficiency. Separation from carrier gas by sieving, aerodynamic sorting, settling, elution. Filtration and factors affect it, mechanisms, media and filtration devices. Blending Powders - Mechanism of random mixing and interacting components. Sampling, sample size and effectiveness indicators. Factors affecting: component ratio, particle size, shape and density, moisture, static electricity, mixing chamber filling rate. Types, characteristics and function of mixers. Drying - Definitions. Measurement of humidity. Drying theory, modes of moisture migration, heat transfer mechanisms, drying times, equilibrium humidity and material behavior. Dryer types. Lyophilization - Principles of lyophilisation and applications in pharmaceuticals. The practical exercises of the students concern the processes of grinding, mixing and drying that are taught in the class. Computer programs are used to process the results.
Educational Material Types
  • Notes
  • Slide presentations
  • Book
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Laboratory Teaching
  • Use of ICT in Communication with Students
Software spreadsheets are used to record, analyze, tabulate and process data on a computer. Dedicated logging software that supports RS232 connection mode is used to automatically transfer and record data from computer-to-computer devices. Optional statistical software (SPSS and ExpertDesign) is used to analyze and compare data from different student groups. The presentation of the lectures is mainly electronic by computer viewing the slides of the lesson as well as educational demonstration videos of the device operation. For explanation, a Wooden Table is used. For the internship there is the possibility to use the library and computers of the islet of the sector. Software (Microsoft Excel) spreadsheets are used to record, analyze, tabulate and process data on a computer. Software used (supplied by A & D electronic weighing machine manufacturer) that supports the RS232 connection function for automatic transfer and recording of data from computer-to-computer devices. Optional statistical software (SPSS and ExpertDesign) is used to analyze and compare data from different student groups.
Course Organization
Laboratory Work50
Student Assessment
The students have to present written report with a detailed description of the labware, instruments and methods used in the experiments, following instructions detailed in the laboratory exercise leaflet. Also to present the results on appropriate charts and comment on them by comparing them with those of other groups. Upon handing their report of their laboratory work the students are examined orally and written examination takes place at the end of the semester.
Student Assessment methods
  • Written Exam with Short Answer Questions (Summative)
  • Written Exam with Extended Answer Questions (Summative)
  • Written Assignment (Formative)
  • Oral examination of the work during the practical classes
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