Specific Organic Chemistry

the finalization of this course will make the students familiar to the basic principles of Specific Organic Chemistry (this course belongs to the background courses). The taken knowledge will be helpful in the undesrstading of the courses of Pharmaceutical Chemistry in the following semesters, as well in the understanding of the function and activity of the biomolecules and their interaction to other simple molecules. With this knowledge they could be helped to solve basic problems of organic chemistry as professionals in the field of drugs synthesis in the Pharmaceutical industry

Basic concepts of organic spectroscopy. IR, MS, NMR, UV-Vis spectra Conjugated p-systems and pericircular reactions Aromatic compounds Aromatic substitution reactions Aldehydes and ketones Carboxylic acids and their derivatives Chemistry of α-carbon. Enols and enol ions Amines Chemistry of biomolecules (carbohydrates, amino acids, peptides, proteins, lipids, nucleic acids) Laboratory Exercises: Safety rules in the chemical laboratory. Learning the basic techniques of the organic laboratory (recrystallization, distillation, extraction, drying, chromatography, determination of m.p. and m.p., reflux). Simple organic synthetic reactions.

28-03-2021