Learning Outcomes
The students will be able to :
- know the mechanisms of microbial growth
- know several bioreactors
- know the major aerobic and anaerobic industrial food bioprocesses
- describe the microbial growth and product formation using specific equations
- know the main cell and enzymes immobilization techniques
Course Content (Syllabus)
Lectures
Introduction
Microbial growth (Batch systems, continuous systems etc.)
Enzymes
Operating Considerations for Bioreactors for Suspension and Immobilized Cultures
Selection, Scale-Up, Operation, and Control of Bioreactors
Recovery and Purification of Products
Mixed Cultures - Utilizing Genetically Engineered Organisms
Traditional Industrial Bioprocesses(aerobic)
Traditional Industrial Bioprocesses(anaerobic)
Laboratory
A. Microbial growth in a closed system
(A1): Microbial growth curve
(A2): Specific growth rate μ
(A3): Consumption of Limiting Substrate - Biomass yield
B. Microbial metabolism - Products
(B1): Metabolic products curves - products yield
(B2): Stoichiometry of Microbial Growth and Product Formation
C. Bioreactors
(C1): Continuous systems - Fermentor - Applications of fermentation systems
(C2): Fixed bed bioreactor - Immobilization of biocatalysts
Keywords
bioprocesses, fermentation systems, bioreactors, enzymes, immobilization
Additional bibliography for study
1. Σημειώσεις εργαστηριακών ασκήσεων "Βιοδιεργασίες στην Επιστήμη Τροφίμων"
2. Μικροβιολογία και Μικροβιακή Τεχνολογία, Αγγελής Γεώργιος, UNIBOOKS ΙΚΕ, 2017
3. Bioprocess Engineering: Basic Concepts, 3rd Edition, Michael L. Shuler, Fikret Kargi,Matthew DeLisa, 2017,Pearson
4. Bioprocess Engineering Kinetics, Sustainability, and Reactor Design, 2nd Edition, Shijie Liu,Elsevier, 2017. https://doi.org/10.1016/C2015-0-04891-2