Biology of stem cells

Course Information
TitleΒιολογία Βλαστοκυττάρων / Biology of stem cells
CodeΜΒΑΙ002
FacultyHealth Sciences
SchoolMedicine
Cycle / Level2nd / Postgraduate
Teaching PeriodWinter
CoordinatorGeorgios Koliakos
CommonNo
StatusActive
Course ID600019322

Programme of Study: IPPS Stem Cells and Regenerative Medicine

Registered students: 20
OrientationAttendance TypeSemesterYearECTS
CoreCompulsory Course117.5
Class Information
Academic Year2023 – 2024
Class PeriodWinter
Faculty Instructors
Instructors from Other Categories
Class ID
600241609
Course Type 2021
Specialization / Direction
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction, Examination)
Learning Outcomes
Familiarization of students with the specialized characteristics of different types of stem cells Understanding the biological properties of stem cells Acquaintance with medical applications and perspectives in the context of regenerative medicine In particular, the potential for tissue and organ creation and the development of new therapeutic approaches
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Adapt to new situations
  • Make decisions
  • Work autonomously
  • Work in teams
  • Work in an international context
  • Work in an interdisciplinary team
  • Generate new research ideas
  • Advance free, creative and causative thinking
Course Content (Syllabus)
Stem cells in biology and medicine Why is it worth studying them? When is a cell a stem cell (or which cells are not stem cells)? Molecular basis of Stemness-Pluripotency Signaling – Gene Regulation – Differentiation in stem cells Translational and post-translational regulation in stem cells Epigenetic Mechanisms-cellular memory and differentiation The extracellular matrix and stem cell niches Regulation of the cell cycle in adult stem cells Mechanisms of ageing and renewal of stem cells Cell fusion and inter-differentiation. Mesenchymal stem cells (MSCs) Embryonic Stem Cells (ESCs) and induced Pluripotent Stem Cells (iPSCs) Hematopoietic (HSCs) and Mesenchymal Stem Cells (MSCs) of Tissues: Characteristics, Properties and Differentiation Potential Monocytes and Pluripotent Stem Cells derived from Monocytes Very small embryonic-like stem cells (VSEL) Stem Cells in the Nervous System Stem cells in the eye and ear Stem cells in the skin and hair follicles Precursor endothelial cells and vascular stem cells Bone and joint stem cells Stem cells and myocardial regeneration Stem cells in the lung Stem cells in the liver, pancreas, and kidney Stem cells in the gastrointestinal tract
Keywords
Stem cells, Embryonic stem vells, Induced Pluripotent stem cells, Adult stem cells, Very small embryonic like stem cells, differentiation,
Educational Material Types
  • Notes
  • Slide presentations
  • Book
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures✓✓
Written assigments✓
Exams✓
Total
Student Assessment
Description
Students are evaluated by the instructors on the basis of their participation in the course with questions or their ability to answer questions of the instructor. Students deliver and present a written thesis-bibliographic review on a specific topic that interests them, thus learning to refer to the literature and follow scientific developments.
Student Assessment methods
  • Written Assignment (Formative)
  • Oral Exams (Formative)
Bibliography
Additional bibliography for study
Molecular Biology of the Cell Bruce Alberts seventh edition Northon Molecular Cell Biology Lodish forth edition Freeman, Essentials of stem cell Biology Lanza 3rd edition academic press Human Stem Cell Technology and Biology: A Research Guide and Laboratory Manual Gary Stein Wiley-Blackwell
Last Update
21-12-2023