Bio-Pharmaceutical Technology
| Title | Βιο-Φαρμακευτική Τεχνολογία / Bio-Pharmaceutical Technology |
| Code | ΒΦ2 |
| Faculty | Engineering |
| School | Chemical Engineering |
| Cycle / Level | 2nd / Postgraduate, 3rd / Doctorate |
| Teaching Period | Winter/Spring |
| Coordinator | Andreana Assimopoulou |
| Common | Yes |
| Status | Active |
| Course ID | 600023190 |
Programme of Study: MSc Chemical and Biochemical Engineering: Health & Food
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Compulsory Course | 2 | 1 | 7.5 |
| Academic Year | 2024 – 2025 |
| Class Period | Spring |
| Faculty Instructors | |
| Class ID | 600245281
|
Course Type 2021
General Foundation
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600245281
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
- η γλώσσα διδασκαλιας θα είναι αγγλική εφόσον υπάρχουν αγγλόφωνοι φοιτητές
Prerequisites
General Prerequisites
-
Learning Outcomes
Upon successful completion of the course, students are expected to:
- be introduced to the general concepts of pharmaceuticals, in the process of discovery and development of drugs
-they will learn about Scaling up production in the pharmaceutical industry, the industrial production of medicines, the rules of good manufacturing practice, quality control in a pharmaceutical industry.
- to learn about the basic pharmaceutical formulations in which medicines are available
- to familiarize themselves with the presentation of a topic related to the subject
- to understand connection of the laboratory with the industrial scale
- to conduct laboratories on the production of pharmaceuticals and connect theory with practice
The aim is to introduce students to the interesting field of the bio-pharmaceutical industry and drug quality control and to determine the position of the chemical engineer in it. The subject has been adapted to the directions and level of postgraduate studies and provides the foundations, but also the stimulus and motivation for students who want to specialize further or within the framework of a doctoral thesis in medicines(discovery and development).
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Adapt to new situations
- Make decisions
- Work autonomously
- Generate new research ideas
- Respect natural environment
- Be critical and self-critical
- Advance free, creative and causative thinking
Course Content (Syllabus)
Introduction. Basic terms and definitions
Drug Discovery and Development process
Innovation in the Pharmaceutical Industry
New (innovative) drugs - Generic drugs -Biosimilars
Drug properties: solubility-particle size
Intro to Pharmacokinetics
Pharmacodynamics – Bioavailability-Bioequivalence
Analysis of pharmaceuticals
Quality control of Pharmaceuticals – Good manufacturing practices- Pharmaceutical Quality by Design (QbD)
Scale up in the pharmaceutical industry: from lab to industrial production -Case studies
Scale up vs scale-out, Single Use technologies – Spatial planning of the pharmaceutical industry (Negative/positive pressure rooms, gowning/degowning, personnel and material flow)
Pharmaceutical process development
The drug manufacturing process
Tablet-Capsules-Ointments-Creams -Emulsions-Suspensions
Drug Delivery - Diffusion and Dissolution of Drugs
Stability – Shelf life of pharmaceuticals
Laboratory: extraction methods, production of ointments-creams
Educational Material Types
- Notes
- Slide presentations
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Communication with Students
- Use of ICT in Student Assessment
Description
The whole lecture is available through e-learning platform- all the communication with the students is performed through e-learning. There are available on line methods of scientific literature search.
Several assays of the students are presented through powerpoint in subjects related to the subject.
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 33 | 1.1 | ✓ | ||
| Laboratory Work | 3 | 0.1 | ✓ | ✓ | |
| Reading Assigment | 113 | 3.8 | ✓ | ||
| Interactive Teaching in Information Center | 3 | 0.1 | |||
| Written assigments | 70 | 2.3 | ✓ | ||
| Exams | 3 | 0.1 | |||
| Total | 225 | 7.5 |
Student Assessment
Description
Written exam: 80% - Bibliographic assay 20% (mandatory).
Student Assessment methods
- Written Exam with Short Answer Questions (Formative, Summative)
- Written Exam with Extended Answer Questions (Formative, Summative)
- Report (Formative, Summative)
- Labortatory Assignment (Formative, Summative)
Bibliography
Course Bibliography (Eudoxus)
1. Α. Ασημοπούλου: Βιο-Φαρμακευτική Τεχνολογία, Σημειώσεις Μαθήματος (διανέμονται μέσω elearning στους εγγεγραμμένους φοιτητές)
2. ΚΩΝΣΤΑΝΤΙΝΟΣ ΔΕΜΕΤΖΟΣ. Φαρμακευτική Νανοτεχνολογία,
Κωδικός Βιβλίου στον Εύδοξο: 41959388
Έκδοση: 1η/2014
ISBN: 978-960-394-988-6
Διαθέτης (Εκδότης): ΠΑΡΙΣΙΑΝΟΥ ΑΝΩΝΥΜΗ ΕΚΔΟΤΙΚΗ ΕΙΣΑΓΩΓΙΚΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΙΑ ΕΠΙΣΤΗΜΟΝΙΚΩΝ ΒΙΒΛΙΩΝ
Additional bibliography for study
(μέσω elearning)& scopus, sciencedirect, google scholar
Last Update
03-06-2025
