Clinical Biochemistry
| Title | Κλινική Βιοχημεία / Clinical Biochemistry |
| Code | ΙΑ1024 |
| Faculty | Health Sciences |
| School | Medicine |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Coordinator | Kali Makedou |
| Common | No |
| Status | Active |
| Course ID | 600017875 |
Programme of Study: UPS of School of Medicine (2019-today)
Registered students: 402
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Compulsory Course | 4 | 2 | 4 |
| Academic Year | 2023 – 2024 |
| Class Period | Spring |
| Faculty Instructors |
|
| Class ID | 600250776
|
| Section | Instructors |
|---|---|
| 1. Ομάδα ε1 | |
| 2. Ομάδα ε2 | |
| 3. Ομάδα ε3 | |
| 4. Ομάδα ε4 | |
| 5. Ομάδα ε5 | |
| 6. Ομάδα ε6 | |
| 7. Ομάδα ε7 | |
| 8. Ομάδα ε8 | |
| 9. Ομάδα ε9 | |
| 10. Ομάδα ε10 | |
| 11. Ομάδα ε11 | |
| 12. Ομάδα ε12 | |
| 13. Ομάδα ε13 | |
| 14. Ομάδα ε14 | |
| 15. Ομάδα ε15 | |
| 16. Ομάδα ε16 | |
| 17. Ομάδα ε17 | |
| 18. Ομάδα ε18 |
Class Schedule
| Building | Ιατρικής (Β) |
| Floor | Ισόγειο |
| Hall | ΑΜΦΙΘΕΑΤΡΟ ΑΝΑΤΟΜΕΙΟΥ ΑΛΕΞΑΝΔΡΟΥ ΣΑΒΒΑ (74) |
| Calendar | Δευτέρα 12:00 έως 13:00 |
| Building | Ιατρικής (Β) |
| Floor | Ισόγειο |
| Hall | ΑΜΦΙΘΕΑΤΡΟ ΑΝΑΤΟΜΕΙΟΥ ΑΛΕΞΑΝΔΡΟΥ ΣΑΒΒΑ (74) |
| Calendar | Τρίτη 12:00 έως 13:00 |
| Building | Ιατρικής (αμφιθέατρο) |
| Floor | Όροφος 1 |
| Hall | ΑΜΦΙΘΕΑΤΡΟ Β (73) |
| Calendar | Τρίτη 13:00 έως 14:00 |
| Building | Ιατρικής (αμφιθέατρο) |
| Floor | Όροφος 1 |
| Hall | ΑΜΦΙΘΕΑΤΡΟ Β (73) |
| Calendar | Τετάρτη 13:00 έως 14:00 |
Course Type 2021
Specific Foundation
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600250776
- At the Website of the School: https://www.med.auth.gr/course/kliniki-viohimeia-0
- eLearning: https://elearning.auth.gr/course/view.php?id=14965
Erasmus
The course is also offered to exchange programme students.
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
Prerequisites
Required Courses
- ΙΑ1004 General Biochemistry
- ΙΑ1011 Biochemistry I
- ΙΑ1018 Biochemistry II
Learning Outcomes
By the end of the semester, students will be able to know the biochemical and molecular basis of the pathophysiology of different diseases in the vast spectrum of Internal Medicine and Surgery. They will be acquainted with all those lab exams necessary for the investigation of diseases and their interpretation, and they will have understood the clinical significance of the assessment of biochemical parameters and biomarkers in the prevention, diagnosis and treatment follow-up in different pathological conditions and diseases.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Make decisions
- Work in teams
- Work in an interdisciplinary team
- Respect natural environment
- Be critical and self-critical
Course Content (Syllabus)
Courses are held in Amphitheatre B
Tuesday and Wednesday 13:00-14:00
Course curriculum:
Evaluation of laboratory assays and results. Internal and external quality control, calibration of biochemical analyzers, reference values, sensitivity, specificity, negative prognostic values, ROC curves
Evaluation of renal function. Biochemical tests of renal function. Acute and chronic renal disease.
Hydrogen and clinical significance. Hydrogen ion homeostasis-buffering. Laboratory investigation of disorders of hydrogen ion homeostasis-non-respiratory acidosis, respiratory acidosis, non-respiratory alkalosis, respiratory alkalosis.
The laboratory of Clinical Biochemistry. Description of the departments and instrumentation of a clinical biochemistry laboratory – preparation for the visit in the Laboratory of Biochemistry in AHEPA Hospital.
Bone metabolism: Calcium and phosphate. Regulation of calcium and phosphate metabolism. Laboratory evaluation of hypercalcaemia, hypocalcemia, hyperphaphatemia and hypophosphatemia.
Lipids and biochemistry of the cardiovascular system. Laboratory evaluation of dyslipidemias and cardiovascular disorders
Evaluation of glucose metabolism. Laboratory investigation of Diabetes mellitus
Disorders of serum proteins
Immunology in Clinical Biochemistry. Innate and adaptive immune system. Antigen recognition, complement, acute phase proteins, cytokines. Laboratory investigation of immune deficiencies and autoimmune disorders.
Laboratory assessment of the hepatic function
Clinical biochemistry of the gastrointestinal tract. Laboratory assessment of nutrients malabsorption, inflammatory bowel disease and pancreatitis.
Hemoglobinοpathies
Anemias
Disorders of coagulation
Hypothalamic and pituitary disorders
Thyroid dysfunction
Clinical Biochemistry of adrenal disorders
Molecular Clinical Biochemistry. Laboratory of molecular genetics laboratory - description
Molecular laboratory-techniques of genetic analysis
Biomarkers of cancer
Clinical Biochemistry of nutrition
Clinical Biochemistry of muscle disease
Clinical Biochemistry of neurological disease
Therapeutic drug monitoring. Pharmacokinetics, pharmacodynamics, optimal therapeutic drug
levels
Poisoning. Etiology, laboratory investigation, anti-inflammatory drugs, antiepileptics, acetaminophen (paracetamol), ethanol
Keywords
Clinical Biochemistry, Biomarkers, laboratory investigation
Educational Material Types
- Notes
- Slide presentations
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
- Use of ICT in Student Assessment
Description
The use of new technology and multimedia is fundamental in the teaching of Clinical Biochemistry; all biochemical determinations during the laboratory exercise of the students take place by using specific instruments, such as spectrophotometers; lectures are given by the use of multimedia; students may get in contact with their Professors directly, via elearning and via email. Finally, for the evaluation of students at the end of the laboratory lessons a quiz is given via elearning and the examination of Clinical Biochemistry as a course at the end of the semester is computer-based as it takes place via ZOOM.
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 90 | 3.2 | |||
| Laboratory Work | 12 | 0.4 | |||
| Written assigments | 10 | 0.4 | |||
| Total | 112 | 4 |
Student Assessment
Description
For students' evaluation 2 (two) grades are required:
1. Lab grade (20% of the total) including written electronic lab exam with multiple choise questions (70% of Lab grade) and reports (30% of lab grades)
2. Final written exam (80% of the total) with multiple choise questions and questions of short answer, electronically in the amphitheater, with the use of the tablets of Medical School.
Student Assessment methods
- Written Exam with Multiple Choice Questions (Summative)
- Written Exam with Short Answer Questions (Summative)
- Labortatory Assignment (Summative)
- γραπτή Εργαστηριακή εξέταση (Summative)
Bibliography
Course Bibliography (Eudoxus)
1. Wiliam J.Marshall, Marta Lapsley, Andrew P. Day, Ruth M. Ayling . Κλινική Βιοχημεία (2021). Εκδόσεις Utopia (Κωδικός στον ΕΥΔΟΞΟ: 94689642)
2. Gaw Allan,Cowan Robert A.,O’Reilly Dennis S. J.,Stewart Michael J.,Shepherd James. Κλινική Βιοχημεία (2010) ΠΑΡΙΣΙΑΝΟΥ Α.Ε. (Κωδικός στον ΕΥΔΟΞΟ: 42049)
Last Update
22-09-2024
