Learning Outcomes
The aim of this course is learning and understanding
-the biochemistry of nucleic acid and particularly the biochemical mechanisms by which the genetic information is replicated, expressed and regulated.
-the biochemical and molecular basis of the immune system, sensory organs, and certain other tissues (e.g., connective tissue, blood, muscle tissue, etc.) as well as the teaching of the biochemical basis of the respective diseases.
Course Content (Syllabus)
DNA replication, mutagenesis and repair. RNA transcription and processing. Protein synthesis and post-translational modifications. Control and regulation of gene expression. Recombinant DNA technology. Molecular basis of cancer. Hepatic metabolism. Biochemistry of the blood (metabolism, clotting and fibrinolysis), immune, nervous, muscular and sensory systems. Biochemistry of extracellular matrix and connective tissue. The action of hormones on metabolism.
Keywords
Replication, transcription, translation, gene regulation, cancer, hormones, connective tissue, recombinant DNA, tissue metabolism
Course Bibliography (Eudoxus)
Biochemistry, Berg JM, Tymoszko JL, Gatto GJ., Stryer L. 9th Edition
Marks Basic Medical Biochemistry, Lieberman M., Marks AD. 5th Edition