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Curriculum Vitae

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George Karakiulakis

Professor (Retired), School of Medicine

Personal Information

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- 2310999304
- 2310999303
gkaraki@auth.gr
Scopus ID7003512301
PubMed IDKarakiulakis+G
Γνωστικό Αντικείμενο:
Φαρμακολογία
Επιστημονική Ειδίκευση: Ιατρική421, 721, Φαρμακολογία

Education

Προπτυχιακές Σπουδές

1975	B.Sc. (Honours) Pharmacology School of Pharmacy Portsmouth University Great Britain
2003	Πτυχίο Ιατρικής Ιατρική Σχολή ΑΠΘ Greece

Μεταπτυχιακές Σπουδές

1976	M.Sc. Biochemistry School of Pharmacy Chelsea College (Kings College), London Univeristy Great Britain

Διδακτορικό Δίπλωμα

1979	Ph.D. School of Pharmacy Chelsea College (Kings College), London Univeristy Great Britain

Course Work

Courses of Winter semester of 2018–19 academic year

	TMĪMA IATRIKĪS
ΙΑ0340	Pharmacology II

Courses of Spring semester of 2018–19 academic year

	TMĪMA IATRIKĪS
ΙΑ0293	Clinical Pharmacology
ΙΑ0339	Pharmacology I

Theses Supervised

Student Theses within AUTh

In progress

Spachos Dimitrios. Τεχνολογίες σημασιολογικού ιστού σε ανοικτά, διασυνδεδεμένα ιατρικά δεδομένα
Tsatsou Fragkiski. Διερεύνηση του ρόλου των μορίων του εξωκυττάριου χώρου στην παθοφυσιολογία της πυώδους ιδρωταδενίτιδας

2012–2013

Cholevas Christos. Επίδραση των φαρμάκων θεραπείας πνευμονικής υπέρτασης στην έκφραση των γλυκοζαμινογλυκανών και μεταλλοπρωτεασών σε πρωτογενείς καλλιέργειες λείων μυϊκών κυττάρων πνευμονικής αρτηρίας

2010–2011

Tzellos Thrasyvoulos. Μελέτη της έκφρασης των μορίων του εξωκυτταρίου στρώματος στην ενδογενή και εξωγενή δερματική γήρανση.

2005–2006

Fachantidīs Panagiōtīs. Μελέτη της επίδρασης της ισοτρετινοϊνης στις κολλαγονάσες του συνδετικού ιστού στο σμήγμα ακμής ασθενών

Administrative Work

Τμήματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
9	2013		Head, Κοσμήτορας Σχολής Επιστημών Υγείας
8	2012	2013	Head, Επιτροπή Διδακροτικών Διατριβών
6	2011	2014	Director, Ά Εργαστήριο Φαρμακολογίας
3	2009	2013	Head, ΟΜΕΑ ΙΣΑΠΘ
7	2009	2012	Head, Θέσπισης Κριτηρίων Αξιολόγησης Μελών ΔΕΠ ΙΑτρικής Σχολής
2	2008	2013	Member, Συντονιστική Επιτροπή Μεταπτυχιακών Σπουδών του Π.Μ.Σ.Ι. "Ιατρική Ερευνητική Μεθοδολογία"
5	2007	2011	Director, Β Εργαστήριο Φαρμακολογίας
4	2007	2009	Director, Τομέας Φυσιολογίας-Φαρμακολογίας
1	2000	2012	Member, Επιτροπή Διδακροτικών Διατριβών

Ιδρύματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
2	2013	2016	Member, ΜΟΔΙΠ
1	2010	2012	Member, Έργο ΜΟΔΙΠ

Research Projects

2013–2013	Ενίσχυση των ερευνητικών υποδομών ή δραστηριοτήτων της Κοσμητείας της Σχολής Επιστημών Υγείας
2009–2011	Ιδιοπαθής πνευμονική αρτηριακή υπέρταση(IPAH) :Διερεύνηση του ρόλου των γλυκοζαμινογλυκανών (GAG) στην παθοφυσιολογία της IPAH και της επίδρασης της φαρμακοθεραπείας στην ομοιόσταση των GAG σε πρωτογενείς καλλιέργειες λείων μυϊκών κυττάρων πνευμονικής αρτηρίας ασθενών
2006–2008	Διερεύνηση βιοχημικών παραμέτρων που σχετίζονται με την καλοήθη υπερπλασία του προστάτη αδένα και ο συσχετισμός τους, ως προδιαθεσικών παραγόντων , για καρκίνο του προστάτη.
2004–2009	Πνευμονική ίνωση, χρόνια αποφρακτική πνευμονοπάθεια και άσθμα: διερεύνηση της παθοφυσιολογίας και της φαρμακοθεραπείας σε σχέση με τα μόρια του συνδετικού ιστού, χρησιμοποιώντας πρωτογενείς καλλιέργειες κυττάρων ανθρώπινου πνεύμονα από ασθενείς
2004–2004	Συνέδριο: "3ο Πανελλήνιο Συνέδριο Φαρμακολογίας".
1997–1997	Investigation of the role of glycans in arteriosclerosis
1992–	Μελέτη του μηχανισμού αγγειογένεσης με time iapse video microscopy και ανάπτυξη αντιαγγειογενετικών ουσιών

Publications

2015

Journal Article

Papakonstantinou Eleni, Karakiulakis George, Batzios S, Savic S, Roth M, Tamm M, Stolz D (2015). Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection. Respiratory Research. vol. 16 no. 1 p. 78.
Papakonstantinou Eleni, Roth M, Klagas I, Karakiulakis George, Tamm M, Stolz D (2015). COPD exacerbations are associated with pro-inflammatory degradation of hyaluronic acid. Chest. vol. 148 no. 6 p. 1497-1507.

2014

Journal Article

Hostettler KE, Zhong J, Papakonstantinou Eleni, Karakiulakis George, Tamm M, Seidel P, Sun Q, Mandal J, Lardinois D, Lambers C, Roth M (2014). Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis. Respiratory Research. vol. 12 no. 15 p. 157.
Praidou A, Androudi S, Brazitikos Periklis, Karakiulakis George, Papakonstantinou Eleni, Tsinopoulos Ioannis, Dimitrakos Stavros (2014). Diabetic retinopathy treated with laser photocoagulation and the indirect effect on glycaemic control. Journal of Diabetes Research. Vol. 2014.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Georgalas I, Rotsos T, Karakiulakis George, Diza-Mataftsi Evdoxia, Dimitrakos Stavros (2014). Comparison of interleukin-6 and matrix metalloproteinase expression in the subretinal fluid and the vitreous during proliferative vitreoretinopathy: correlations with extent, duration of RRD and PVR grade. Cytokine. Vol. 67 no. 2 p. 71–76.
Symeonidis Nikolaos, Papakonstantinou Eleni, Psarras Kyriakos, Ballas Konstantinos, Pavlidis Theodoros, Karakiulakis George, Sakantamis Athanasios (2014). The effect of celecoxib administration on the healing and neovascularization of colonic anastomosis in rats. Journal of Investigative Surgery. vol.27 no.3 p.139-146.

2013

Journal Article

Dadoukis P, Klagas I, Komnenou A, Karakiulakis George, Karoutis A, Karampatakis Vasileios, Papakonstantinou Eleni (2013). Infrared irradiation alters the expression of matrix metalloproteinases and glycosaminoglycans in the cornea and crystalline lens. Graefe's Archive for Clinical and Experimental Ophthalmology. vol.251 no.8 p.1929-36.
Kovatsi Leda, Batzios S, Nikolaou K, Fragou D, Njau S, Tsatsakis A, Karakiulakis George, Papakonstantinou Eleni (2013). Alterations in serum MMP and TIMP concentrations following chronic heroin abuse. Toxicology Mechanisms and Methods. vol. 23 no. 5 p. 377-381.

2012

Journal Article

Karakiulakis George, Roth M (2012). Muscarinic receptors and their antagonists in COPD: anti-inflammatory and antiremodeling effects. Mediators Inflamm. vol.2012.
Papakonstantinou Eleni, Roth M, Karakiulakis George (2012). Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. vol.4 no.3 p.253-8.
Papakonstantinou Eleni, Klagas I, Karakiulakis George, Hostettler K, S'ng C.T, Kotoula-Dimitriadou Vasiliki, Savic S, Tamm M, Roth M (2012). Steroids and β2 Agonists Regulate Hyaluronan Metabolism in Asthma Airway Smooth Muscle Cells. American Journal Respiratory Cell and Molecular Biology. Published Version. Vol. 47 no. 6 p. 759-767.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Tsaousis K.T, Tsinopoulos Ioannis, Brazitikos P, Karakiulakis George, Diza-Mataftsi Efdoxia, Dimitrakos Stayros (2012). Interleukin-6 and matrix metalloproteinase expression in the subretinal fluid during proliferative vitreoretinopathy: correlation with extent, duration of RRD and PVR grade. Cytokine. Published Version. vol.59 no.1 p.184-190.

2011

Journal Article

Batzios SP, Zafeiriou Dimitrios, Vargiami Efthymia, Karakiulakis George, Papakonstantinou Eleni (2011). Differential expression of matrix metalloproteinases in the serum of patients with mucopolysaccharidoses. Journal of Inherited Metabolic Disease. vol.3 p.59-66.
Praidou A, Papakonstantinou Eleni, Androudi S, Georgiadis Nikolaos, Karakiulakis George, Dimitrakos Stavros (2011). Vitreous and serum levels of vascular endothelial growth factor and platelet-derived growth factor and their correlation in patients with non-proliferative diabetic retinopathy and clinically significant macula oedema. Acta Οphthalmologica. vol.89 no.3 p.248-254.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Rotsos T, Diza-Mataftsi Efdoxia, Brazitikos P, Karakiulakis George, Dimitrakos Stayros (2011). Interleukin-6 and the matrix metalloproteinase response in the vitreous during proliferative vitreoretinopathy. Cytokine. Published Version. vol.54 no.2 p.212-217.
Symeonidis Chrysanthos, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Karakiulakis George, Dimitrakos Stayros, Diza-Mataftsi Evdoxia (2011). Correlation of matrix metalloproteinase levels with the grade of proliferative vitreoretinopathy in the subretinal fluid and vitreous during rhegmatogenous retinal detachment. Acta ophthalmologica. Published Version. vol.89 no.4 p.339-345.
Tzellos T.G, Batzios S.P, Dionysopoulos Alexandros, Karakiulakis George, Papakonstantinou Eleni (2011). Differential expression of matrix metalloproteinases and proteoglycans in Juvenile Hyaline Fibromatosis. Journal of Dermatological Sciences. Published Version. vol.61 no.2 p.94-100.
Tzellos Thrasivoulos, Kyrgidis Athanasios, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Klagas I, Zvintzou E, Kritis Aristeidis, Karakiulakis George, Papakonstantinou Eleni (2011). Nodular basal cell carcinoma is associated with increased hyaluronan homeostasis. Journal of the European Academy of Dermatology and Venereology. Published Version. Vol.25 no.6 p. 679-687.
Tzellos Thrasivoulos, Sinopidis Xenophon, Kyrgidis Athanasios, Klagas Ioannis, Karakiulakis George, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Papakonstantinou Eleni (2011). Differential hyaluronan homeostasis and expression of proteoglycans in juvenile and adult human skin. Journal of Dermatological Science. Published Version. Vol. 61 no. 1 p. 69–72.

2010

Journal Article

Praidou Anna, Androudi Sοphia, Brazitikos Periklis, Karakiulakis George, Papakonstantinou Eleni, Dimitrakos Stayros (2010). Angiogenic growth factors and their inhibitors in diabetic retinopathy. Current Diabetes Reviews. Published Version. vol.6 no.5 p.304-312.
Tzellos T, Papakonstantinou Eleni, Sinopidis X, Vachtsevanos Konstantinos, Kyrgidis A, Triaridis Stefanos, Printza Athanasia, Klagas I, Zvintzou E, Karakiulakis George (2010). Differential expression of preoteoglycans in intrinsic and extrinsic skin ageing. Review of Clinical Pharmacology and Pharmacokinetics, International Edition. vol.24 no.2.

2009

Journal Article

Klagas I, Goulet S, Karakiulakis George, Zhong J, Baraket M, Black J.L, Papakonstantinou Eleni, Roth M (2009). Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD. The European Respiratory Journal. Published Version. vol.34 no.3 p.616-628.
Papakonstantinou Eleni, Karakiulakis George (2009). The ‘sweet’ and ‘bitter’ involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance. British Journal of Pharmacology. vol.157 no.7 p.1111-1127.
Papakonstantinou Eleni, Karakiulakis George (2009). The 'sweet' and 'bitter' involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance. British journal of pharmacology. Published Version. vol.157 no.7 p.1111-1127.
Praidou Anna, Klangas I, Papakonstantinou Eleni, Androudi Sophia, Georgiadis-Stefanidis Nikolaos, Karakiulakis George, Dimitrakos Stayros (2009). Vitreous and serum levels of platelet-derived growth factor and their correlation in patients with proliferative diabetic retinopathy. Current Eye Research. Published Version. vol.34 no.2 p.152-161.
Tzellos Thrasivoulos, Klagas I, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Kyrgidis Athanasios, Karakiulakis George, Zouboulis C.C, Papakonstantinou Eleni (2009). Extrinsic ageing in the human skin is associated with alterations in the expression of hyaluronic acid and its metabolizing enzymes. Experimental Dermatology. Published Version. vol.18 no.12 p.1028-1035.
Τzellos Thrasivoulos, Dionysopoulos Alexandros, Klagas I, Karakiulakis George, Lazaridis Charalampos, Papakonstantinou Eleni (2009). Differential glycosaminoglycan expression and hyaluronan homeostasis in juvenile hyaline fibromatosis. Journal of the American Academy of Dermatology. Published Version. vol.61 no.4 p.629-638.

2008

Journal Article

Papakonstantinou Eleni, Kouri F.M, Karakiulakis George, Klagas I, Eickelberg O (2008). Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. The European Respiratory Journal. Published Version. vol.32 no.6 p.1504-1512.
Tzellos Th, Klagas I, Papakonstantinou Eleni, Vachtsevanos Konstantinos, Triaridis Stefanos, Kyrgidis Ath, Printza Athanasia, Zvintzou E, Karakiulakis George (2008). Differential expression of matrix metalloproteinases 2 and 9 in basal cell carcinoma photo-exposed and photo-protected skin. Review of Clinical Pharmacology and Pharmacokinetics International Edition. vol.22 no.2.

2007

Journal Article

Karakiulakis George, Papakonstantinou Eleni, Aletras Alexis, Tamm M, Roth M (2007). Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling. The Journal of Biological Chemistry. Published Version. vol.282 no.2 p.908-915.
Mitropoulos D, Papakonstantinou Eleni, Aletras Alexis, Kalinderis Nikolaos, Zervas Anastasios, Chatzichristou Dimitrios, Karakiulakis George (2007). Terazosin modifies the content of glycosaminoglycans and the activity of matrix metalloproteinase 2 in the rat ventral prostate. European Urology. Published Version. vol.51 no.2 p.447-456.
Symeonidis C, Diza-Mataftsi Efdoxia, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Dimitrakos Stayros, Karakiulakis George (2007). Correlation of the extent and duration of rhegmatogenous retinal detachment with the expression of matrix metalloproteinases in the vitreous. Retina. Published Version. vol.27 no.9 p.1279-1285.
Symeonidis Chrysanthos, Diza-Mataftsi Evdoxia, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Karakiulakis George, Dimitrakos Stayros (2007). Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment. Graefe's archive for Clinical and Experimental Ophthalmology. Published Version. vol.245 no.4 p.560-568.

2006

Journal Article

Tranos P.G, Peter NM, Singh M.V, Nath R, Wren S, Dimitrakos Stavros, Karakiulakis George (2006). Visual function following transpupillary thermotherapy with adjusted laser parameters for the treatment of exudative age-related macular degeneration. A pilot study. Clinical Experimental Ophthalmology. vol. 34 no. 3 p. 226-32.

2005

Journal Article

Papakonstantinou Eleni, Aletras Αlexis, Glass E, Tsogas Panagiotis, Dionyssopoulos A, Adjaye J, Fimmel S, Gouvousis P, Herwig R, Lehrach H, Zouboulis C.C, et al (2005). Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. The Journal of Investigative Dermatology. Published Version. vol.125 no.4 p.673-684.

2004

Journal Article

Papakonstantinou Eleni, Dionyssopoulos A, Aletras Alexis, Pesintzaki Chrisanthi, Minas Aristippos, Karakiulakis George (2004). Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis. Journal of the American Academy of Dermatology. Published Version. vol.51 no.4 p.526-533.

2003

Journal Article

Papakonstantinou Eleni, Aletras Alexis, Roth M, Tamm M, Karakiulakis George (2003). Hypoxia modulates the effects of transforming growth factor-beta isoforms on matrix-formation by primary human lung fibroblasts. Cytokine. Published Version. vol.24 no.1-2 p.25-35.
Papakonstantinou Eleni, Dionyssopoulos A, Pesintzaki Chrisanthi, Minas Aristippos, Karakiulakis George (2003). Expression of proteoglycans and glycosaminoglycans in angiofibroma and fibrous plaque skin lesions from patients with tuberous sclerosis. Archives of Dermatological Research. Published Version. vol.295 no.4 p.138-145.

2002

Journal Article

Papakonstantinou Eleni, Roth M, Tamm M, Eickelberg O, Perruchoud A.P, Karakiulakis George (2002). Hypoxia differentially enhances the effects of transforming growth factor-beta isoforms on the synthesis and secretion of glycosaminoglycans by human lung fibroblasts. The Journal of Pharmacology and Experimental Therapeutics. Published Version. vol.301 no.3 p.830-837.

2001

Journal Article

Karakiulakis George, Papakonstantinou Eleni, Roth M (2001). Assay for cell migration and invasion of vascular smooth muscle cells. Methods Molecular Medicine. Published Version. vol.52 p.163-169.
Papakonstantinou Eleni, Roth M, Karakiulakis George (2001). Isolation and characterization of glycosaminoglycans from human atheromatous vessels. Methods in Molecular Medicine. Published Version. vol.52 p.123-136.
Papakonstantinou Eleni, Roth M, Kokkas Vasileios, Papadopoulos Konstantinos, Karakiulakis George (2001). Losartan inhibits the angiotensin II-induced modifications on fibrinolysis and matrix deposition by primary human vascular smooth muscle cells. Journal of Cardiovascular Pharmacology. Published Version. vol.38 no.5.

2000

Journal Article

Goulas Antonios, Papakonstantinou Eleni, Karakiulakis George, Mirtsou-Fidani Vasiliki, Kalinderis Athanasios, Chatzichristou Dimitrios (2000). Tissue structure-specific distribution of glycosaminoglycans in the human penis. The International Journal of Biochemistry & Cell Biology. Published Version. vol.32 no.9 p.975-982.
Goulas Antonios, Chatzichristou Dimitrios, Karakiulakis George, Mirtsou-Fidani Vasiliki, Kalinderis A, Papakonstantinou Eleni (2000). Benign hyperplasia of the human prostate is associated with tissue enrichment in chondroitin sulphate of wide size distribution. The Prostate. Published Version. vol.44 no.2 p.104-110.
Papakonstantinou Eleni, Karakiulakis George, Tamm M, Perruchoud A.P, Roth M (2000). Hypoxia modifies the effect of PDGF on glycosaminoglycan synthesis by primary human lung cells. American Journal of Physiology. Lung cellular and molecular physiology. Published Version. vol.279 no.5 p.L825-L834.

1999

Journal Article

Papakonstantinou Eleni, Karakiulakis George, Roth M, Verghese-Nikolakaki S, Dawson M, Papadopoulos Orestis, Sklaviadis Theodoros (1999). Glycosaminoglycan analysis in brain stems from animals infected with the bovine spongiform encephalopathy agent. Archives of Biochemistry and Biophysics. Published Version. vol.370 no.2 p.250-257.

1998

Journal Article

Nauck M, Karakiulakis George, Perruchoud A.P, Papakonstantinou Eleni, Roth M (1998). Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells. European Journal of Pharmacology. Published Version. vol.341 no.2-3 p.309-315.
Papakonstantinou Eleni, Roth M, Block L.H, Mirtsou-Fidani Vasiliki, Argiriadis P, Karakiulakis George (1998). The differential distribution of hyaluronic acid in the layers of human atheromatic aortas is associated with vascular smooth muscle cell proliferation and migration. Atherosclerosis. Published Version. vol.138 no.1 p.79-89.
Papakonstantinou Eleni, Karakiulakis George, Eickelberg O, Perruchoud AP, Block L.H, Roth M (1998). A 340 kDa hyaluronic acid secreted by human vascular smooth muscle cells regulates their proliferation and migration. Glycobiology. Published Version. vol.8 no.8 p.821-830.

1997

Journal Article

Karakiulakis George, Papanikolaou C, Jankovic S.M, Aletras A, Papakonstantinou Eleni, Vrettoy Eleni, Mirtsou-Fidani Vasiliki (1997). Increased type IV collagen-degrading activity in metastases originating from primary tumors of the human colon. Invasion & metastasis. Published Version. vol.17 no.3 p.158-168.
Pispirigos K, Paradelis A.G, Karakiulakis George (1997). Evaluation of cardiac subacute toxicity of epirubicin, chlorambucil, cisplatin, methotrexate and a homo-aza-steroid ester with antitumor activity in rats using serum biochemical parameters. Arzneimittel-Forschung. Published Version. vol.47 no.1 p.92-96.
Μήρτσου - Φιδάνη Βασιλική, Μακέδου Καλή, Κούρτη Μ, Καρακιουλάκης Γεώργιος (1997). Εμβρυϊκό Σύνδρομο Αιθυλικής Αλκοόλης. Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής. vol.15 p.84-90.

1995

Journal Article

Pipili-Synetos Eva, Papageorgiou Athanasios, Sakkoula Eleni, Sotiropoulou Georgia, Fotsis T, Karakiulakis George, Maragoudakis Michael E (1995). Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. British Journal of Pharmacology. Published Version. vol.116 no.2 p.1829-1834.

Conference Proceedings Article

Kourti M, Karakiulakis George, Makedou Kali, Mirtsou-Fidani Vasiliki (1995). Clinical manifestations of the Fetal Alcohol Syndrome. 1st European Medical Students’ symposium. 1st European Medical Students’ symposium. Athens.
Makedou Kali, Mirtsou-Fidani Vasiliki, Kourti M, Karakiulakis George (1995). Fetal Alcohol Syndrome: Mechanisms and Prevention. 1st European Medical Students’ symposium. 1st European Medical Students’ symposium.

1994

Journal Article

Bastakis Maria, Missirlis Eleftheria, Klouras Nikolaos, Karakiulakis George, Maragoudakis Michael E (1994). Suppression of angiogenesis by the antitumor agent titanocene dichloride. European Journal of Pharmacology. Published Version. vol.251 no.2-3 p.263-269.

1993

Journal Article

Karakiulakis George, Papakonstantinou Eleni, Maragoudakis Michael E, Misevic GN (1993). Expression of type IV collagen-degrading activity during early embryonal development in the sea urchin and the arresting effects of collagen synthesis inhibitors on embryogenesis. Journal of Cellular Biochemistry. Published Version. vol.52 no.1 p.92-106.
Maragoudakis M.E, Missirlis Eleftheria, Karakiulakis George, Sarmonica Marianna, Bastakis Maria, Tsopanoglou Nikos (1993). Basement membrane biosynthesis as a target for developing inhibitors of angiogenesis with anti-tumor properties. Kidney international. Published Version. vol.43 no.1 p.147-150.
Pispirigos K, Catsoulakos P, Karakiulakis George (1993). Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats. Biochemistry and Μolecular Βiology Ιnternational. Published Version. vol.31 no.3 p.565-573.

1991

Journal Article

Karakiulakis George, Papadimitriou E, Missirlis Eleftheria, Maragoudakis Michael E (1991). Effect of divalent metal ions on collagenase from Clostridium histolyticum. Biochemistry International. Published Version. vol.24 no.3 p.397-404.

1990

Journal Article

Karakiulakis George, Missirlis Eleftheria, Maragoudakis Michael E (1990). Basement membrane collagen-degrading activity from a malignant tumor is inhibited by anthracycline antibiotics. Biochimica et biophysica acta. Published Version. vol.1035 no.2 p.218-222.
Maragoudakis Michael E, Missirlis Eleftheria, Sarmonika Marianna, Panoutsacopoulou Maria, Karakiulakis George (1990). Basement membrane biosynthesis as a target to tumor therapy. The Journal of pharmacology and experimental therapeutics. Published Version. vol.252 no.2 p.753-757.
Missirlis Eleftheria, Karakiulakis George, Maragoudakis Michael E (1990). Antitumor effect of GPA1734 in rat Walker 256 carcinoma. Investigational New Drugs. Published Version. vol.8 no.2 p.145-147.
Missirlis Eleftheria, Karakiulakis George, Maragoudakis Michael E (1990). Angiogenesis is associated with collagenous protein synthesis and degradation in the chick chorioallantoic membrane. Tissue & cell. Published Version. vol.22 no.4 p.419-426.

1989

Journal Article

Anastassiou E.D, Karakiulakis George, Missirlis Eleftheria, Maragoudakis Michael E, Dimitracopoulos George (1989). Comparative evaluation of mitogenicity and basement-membrane-degrading activity of Pseudomonas aeruginosa slime glycolipoprotein and alginate. Journal of Clinical Microbiology. Published Version. vol.27 no.3 p.490-494.
Karakiulakis George, Missirlis Eleftheria, Maragoudakis Michael E (1989). Mode of action of razoxane: inhibition of basement membrane collagen-degradation by a malignant tumor enzyme. Methods and findings in experimental and clinical pharmacology. Published Version. vol.11 no.4 p.255-261.

1988

Journal Article

Karakiulakis George, Missirlis Eleftheria, Aletras Alexis, Maragoudakis Micheal E (1988). Degradation of intact basement membranes by human and murine tumor enzymes. Biochimica et biophysica acta. Published Version. vol.967 no.2 p.163-175.
Papaioannidou Paraskevi, Karakiulakis George, Triantafyllidis Konstantinos, Paradelis A.G (1988). A study of the mechanism of action of aminoglycoside antibiotics on the guinea pig vas deferens. Methods and findings in experimental and clinical pharmacology. Published Version. vol.10 no.9 p.589-584.

1984

Journal Article

Karakiulakis George, Thomas P.J, Papaioannidou Paraskevi, Paradelis A.G (1984). The effects of endogenous and exogenous sex hormones and of maturation on cGMP phosphodiesterase activity in the brain. Methods and findings in experimental and clinical pharmacology. Published Version. vol.6 no.8 p.437-443.

1983

Journal Article

Karakiulakis George, Paradelis A.G, Papaioannidou Paraskevi, Thomas P.J (1983). Maturational aspects of the dopaminergic system: ontogenesis of high affinity dopamine binding to neural membrane fragments of the rat brain. Methods and findings in Experimental and Clinical Pharmacology. Published Version. vol.5 no.10 p.685-694.

1982

Journal Article

Jalilian-Tehrani M.H, Karakiulakis George, Le Blond C.B, Powell R, Thomas P.J (1982). Androgen-induced sexual dimorphism in high affinity dopamine binding in the brain transcends the hypothalamic-limbic region. British Journal of Pharmacology. Published Version. vol.75 no.1 p.37-48.

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Journal Article

Le Blond C.B, Morris S, Karakiulakis George, Powell R, Thomas P.J. Development of sexual dimorphism in the suprachiasmatic nucleus of the rat. The Journal of Endocrinology. Published Version. vol.95 no.1 p.137-145.
Papakonstantinou Eleni, Karakiulakis George, Roth M, Block L.H. Platelet-derived growth factor stimulates the secretion of hyaluronic acid by proliferating human vascular smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. Published Version. vol.92 no.21 p.9881-9885.
Papakonstantinou Eleni, Karakiulakis George, Aletras AJ, Misevic GN. A novel class of adhesion acidic glycans in sea urchin embryos. Isolation, characterization and immunological studies during early embryonal development. European journal of biochemistry. Published Version. vol.224 no.3 p.1067-1077.

Updated: 2018-10-01