Vous êtes ici

Curriculum Vitae

Expand | Collapse

Eleni Papakonstantinou

Professor, School of Medicine

Personal Information

- 2310999367
epapakon@auth.gr
Scopus ID7003948513
PubMed IDPapakonstantinou+E
Επιστημονική Ειδίκευση:
- Βιολογία και βιοχημεία
- Ιατρική

Education

Προπτυχιακές Σπουδές

1987	Πτυχίο Φαρμακευτικής Τμήμα Φαρμακευτικής Πατρών Greece
2008	Πτυχίο Ιατρικής Ιατρική Σχολή Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης Greece

Διδακτορικό Δίπλωμα

1993	PhD Σχολή Φιλοσοφικών και Φυσικών Επιστημών Πανεπιστήμιο Βασιλείας Switzerland Βιοχημεία

Course Work

Courses of Winter semester of 2017–18 academic year

	TMĪMA IATRIKĪS
ΙΑ0340	Pharmacology II

	PROGRAMMA METAPTYCΗIAKŌN SPOUDŌN "EREUNĪTIKĪ METHODOLOGIA STĪN IATRIKĪ KAI STIS EPISTĪMES YGEIAS"
ΙΜΓ100	Methodology for the investigation of the role of extracellular matrix molecules in pathological disorders

	METAPTYCΗIAKO PROGRAMMA SPOUDŌN "TECΗNIKES EXŌSŌMATIKĪS KYKLOFORIAS - TECΗNOLOGIA SYSKEUŌN KARDIOCΗEIROURGIKĪS"
ΜΙΚΓ0014	Phramacology-Anesthesiology

	PROGRAMMA METAPTYCΗIAKŌN SPOUDŌN "KLINIKĪ KAI VIOMĪCΗANIKĪ FARMAKOLOGIA"
ΜΙΦΓ0016	Pharmaceutical Sales

Courses of Spring semester of 2017–18 academic year

	TMĪMA IATRIKĪS
ΙΑ0293	Clinical Pharmacology
ΙΑ0339	Pharmacology I

Theses Supervised

Student Theses within AUTh

In progress

Panagiotou Grigorios.
Gkoma Fani. Παράγοντες που σχετίζονται με την ελλιπή συμμόρφωση ασθενών κατά την αντιρετροΐκή αγωγή για την αντιμετώπιση λοίμωξης από τον ιό της επίκτητης ανοσολογικής ανεπάρκειας

2015–2016

Giannakaki Melpomeni-Maria. Αναγεννητική Ιατρική: Η χρήση μεσεγχυματικών βλαστικών κυττάρων στην αποκατάσταση δερματικών βλαβών

2009–2010

Kalamaras Geōrgios. Διερεύνηση της ενζυμικής δραστηριότητας και της έκφρασης των μεταλλοπρωτεασών του συνδετικού ιστού στην εξωγενή γήρανση του δέρματος
Gouliaros Nikolaos. Διερεύνηση της έκφρασης του υαλουρονικού οξέος σε ανθρώπινα αγγεία με αθηρωμάτωση και σε αγγεία χωρίς αθηρωμάτωση

2008–2009

Mpatzios Spyros. Διερεύνηση της ενζυμικής δραστηριότητας και της έκφρασης των μεταλλοπρωτεασών του συνδετικού ιστού σε παιδιατρικούς ασθενείς με βλεννοπολυσακχαριδώσεις

Administrative Work

Research Projects

2016–2017	Λιπομυοκίνες και μεταλλοπρωτεινάσες του συνδετικού ιστού στον καρκίνο του θυρεοειδή και του μαστού.
2015–2016	Νεότερες λιπομυοκίνες στον καρκίνο του θυρεοειδή και του μαστού και το οξειδωτικό στρες.
2012–2015	Οξεία έξαρση στην ιδοπαθή πνευμονική ίνωση: Μηχανισμός και βιολογικοί δείκτες

Connection to Society

Work Acknowledgement

Work Recognition

Publications

2015

2014

Hostettler KE, Zhong J, Papakonstantinou Eleni, Karakiulakis George, Tamm M, Seidel P, Sun Q, Mandal J, Lardinois D, Lambers C, Roth M (2014). Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis. Respir Res.
Praidou A, Androudi S, Brazitikos Periklis, Karakiulakis George, Papakonstantinou Eleni, Tsinopoulos Ioannis, Dimitrakos Stavros (2014). Diabetic retinopathy treated with laser photocoagulation and the indirect effect on glycaemic control. Journal of Diabetes Research. Vol. 2014.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Georgalas I, Rotsos T, Karakiulakis George, Diza-Mataftsi Evdoxia, Dimitrakos Stavros (2014). Comparison of interleukin-6 and matrix metalloproteinase expression in the subretinal fluid and the vitreous during proliferative vitreoretinopathy: correlations with extent, duration of RRD and PVR grade. Cytokine. Vol. 67 no. 2 p. 71–76.
Symeonidis Nikolaos, Papakonstantinou Eleni, Psarras Kyriakos, Ballas Konstantinos, Pavlidis Theodoros, Karakiulakis George, Sakantamis Athanasios (2014). The effect of celecoxib administration on the healing and neovascularization of colonic anastomosis in rats. Journal of Investigative Surgery. vol.27 no.3 p.139-146.

2013

Dadoukis P, Klagas I, Komnenou A, Karakiulakis George, Karoutis A, Karampatakis Vasileios, Papakonstantinou Eleni (2013). Infrared irradiation alters the expression of matrix metalloproteinases and glycosaminoglycans in the cornea and crystalline lens. Graefes Arch Clin Exp Ophthalmol. vol.251 no.8 p.1929-36.
Kovatsi Leda, Batzios S, Nikolaou K, Fragou D, Njau S, Tsatsakis A, Karakiulakis George, Papakonstantinou Eleni (2013). Alterations in serum MMP and TIMP concentrations following chronic heroin abuse. Toxicology Mechanisms and Methods. vol. 23 no. 5 p. 377-381.
Symeonidis C, Papakonstantinou Eleni, Galli-Tsinopoulou Assimoula, Tsinopoulos Ioannis, Dimitrakos Stavros (2013). Matrix metalloproteinase (MMP-2, -9) and tissue inhibitor (TIMP-1,-2) activity in tear samples of pediatric type 1 diabetic patients: MMPs in tear samples from type 1 diabetes. Graefe's Archive for Clinical and Experimental Ophthalmology. Vol. 251 no. 3 p. 741-749.

2012

Papakonstantinou Eleni, Roth M, Karakiulakis George (2012). Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. vol.4 no.3 p.253-8.
Papakonstantinou Eleni, Klagas I, Karakiulakis George, Hostettler K, S'ng C.T, Kotoula-Dimitriadou Vasiliki, Savic S, Tamm M, Roth M (2012). Steroids and β2 Agonists Regulate Hyaluronan Metabolism in Asthma Airway Smooth Muscle Cells. American Journal Respiratory Cell and Molecular Biology. Published Version. Vol. 47 no. 6 p. 759-767.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Tsaousis K.T, Tsinopoulos Ioannis, Brazitikos P, Karakiulakis George, Diza-Mataftsi Efdoxia, Dimitrakos Stayros (2012). Interleukin-6 and matrix metalloproteinase expression in the subretinal fluid during proliferative vitreoretinopathy: correlation with extent, duration of RRD and PVR grade. Cytokine. Published Version. vol.59 no.1 p.184-190.

2011

Batzios SP, Zafeiriou Dimitrios, Vargiami Efthymia, Karakiulakis George, Papakonstantinou Eleni (2011). Differential expression of matrix metalloproteinases in the serum of patients with mucopolysaccharidoses. Journal of Inherited Metabolic Disease. vol.3 p.59-66.
Praidou A, Papakonstantinou Eleni, Androudi S, Georgiadis Nikolaos, Karakiulakis George, Dimitrakos Stavros (2011). Vitreous and serum levels of vascular endothelial growth factor and platelet-derived growth factor and their correlation in patients with non-proliferative diabetic retinopathy and clinically significant macula oedema. Acta Οphthalmologica. vol.89 no.3 p.248-254.
Symeonidis C, Papakonstantinou Eleni, Androudi S, Rotsos T, Diza-Mataftsi Efdoxia, Brazitikos P, Karakiulakis George, Dimitrakos Stayros (2011). Interleukin-6 and the matrix metalloproteinase response in the vitreous during proliferative vitreoretinopathy. Cytokine. Published Version. vol.54 no.2 p.212-217.
Symeonidis Chrysanthos, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Karakiulakis George, Dimitrakos Stayros, Diza-Mataftsi Evdoxia (2011). Correlation of matrix metalloproteinase levels with the grade of proliferative vitreoretinopathy in the subretinal fluid and vitreous during rhegmatogenous retinal detachment. Acta ophthalmologica. Published Version. vol.89 no.4 p.339-345.
Tzellos T.G, Batzios S.P, Dionysopoulos Alexandros, Karakiulakis George, Papakonstantinou Eleni (2011). Differential expression of matrix metalloproteinases and proteoglycans in Juvenile Hyaline Fibromatosis. Journal of Dermatological Sciences. Published Version. vol.61 no.2 p.94-100.
Tzellos Thrasivoulos, Kyrgidis A, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Klagas I, Zvintzou E, Kritis Aristeidis, Karakiulakis George, Papakonstantinou Eleni (2011). Nodular basal cell carcinoma is associated with increased hyaluronan homeostasis. Journal of the European Academy of Dermatology and Venereology. Published Version. Vol.25 no.6 p. 679-687.
Tzellos Thrasivoulos, Sinopidis Xenophon, Kyrgidis Athanassios, Klagas Ioannis, Karakiulakis George, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Papakonstantinou Eleni (2011). Differential hyaluronan homeostasis and expression of proteoglycans in juvenile and adult human skin. Journal of Dermatological Science. Published Version. Vol. 61 no. 1 p. 69–72.

2010

Bracke K. R, Dentener M. A, Papakonstantinou E, Vernooy J, Demoor T, Pauwels N. S, Cleutjens J, vanS, Joos G. F, Brusselle G. G, Wouters E (2010). Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. Am J Respir Cell Mol Biol. vol.42 no.6 p.753-761.
Mitrou P, Raptis A. E, Lambadiari V, Boutati E, Petsiou E, Spanoudi F, Papakonstantinou E, Maratou E, Economopoulos T, Dimitriadis G, Raptis S. A (2010). Vinegar decreases postprandial hyperglycemia in patients with type 1 diabetes. Diabetes care. vol.33 no.2 p.e27.
Praidou Anna, Androudi Sοphia, Brazitikos Periklis, Karakiulakis George, Papakonstantinou Eleni, Dimitrakos Stayros (2010). Angiogenic growth factors and their inhibitors in diabetic retinopathy. Current Diabetes Reviews. Published Version. vol.6 no.5 p.304-312.
Tzellos T, Papakonstantinou Eleni, Sinopidis X, Vachtsevanos Konstantinos, Kyrgidis A, Triaridis Stefanos, Printza Athanasia, Klagas I, Zvintzou E, Karakiulakis George (2010). Differential expression of preoteoglycans in intrinsic and extrinsic skin ageing. Review of Clinical Pharmacology and Pharmacokinetics, International Edition. vol.24 no.2.

2009

Klagas I, Goulet S, Karakiulakis George, Zhong J, Baraket M, Black J.L, Papakonstantinou Eleni, Roth M (2009). Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD. The European Respiratory Journal. Published Version. vol.34 no.3 p.616-628.
Papakonstantinou E, Yfantis E, Skourbouti A, Georgoutsou P, Lavda A, Paraskevopoulos K, Paximadakis E, Olympios C. D, Manti C (2009). Investigations of Thrombin Generation Tests in Warfarin-Taking Patients. Haematologica-the Hematology Journal. vol.94 p.671-671.
Papakonstantinou Eleni, Karakiulakis George (2009). The 'sweet' and 'bitter' involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance. Br J Pharmacol. vol.157 no.7 p.1111-1127.
Papakonstantinou Eleni, Karakiulakis George (2009). The 'sweet' and 'bitter' involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance. British journal of pharmacology. Published Version. vol.157 no.7 p.1111-1127.
Praidou Anna, Klangas I, Papakonstantinou Eleni, Androudi Sophia, Georgiadis-Stefanidis Nikolaos, Karakiulakis George, Dimitrakos Stayros (2009). Vitreous and serum levels of platelet-derived growth factor and their correlation in patients with proliferative diabetic retinopathy. Current Eye Research. Published Version. vol.34 no.2 p.152-161.
Tzellos Thrasivoulos, Klagas I, Vachtsevanos Konstantinos, Triaridis Stefanos, Printza Athanasia, Kyrgidis A, Karakiulakis George, Zouboulis C.C, Papakonstantinou Eleni (2009). Extrinsic ageing in the human skin is associated with alterations in the expression of hyaluronic acid and its metabolizing enzymes. Experimental Dermatology. Published Version. vol.18 no.12 p.1028-1035.

2008

Hatzipantelis Emmanouil, Gompakis Nikolaos, Sidi V, Papakonstantinou Eleni, Koliouskas Dimitrios (2008). Successful outcome of DIC and life-threatening bleeding in a toddler with neuroblastoma treated with recombinant activated factor VII. Intern Emerg Med. vol.3 no.2 p.171-173.
Moralidis Efstratios-Iordanis, Papakonstantinou Eleni, Arsos Georgios, Boussios N, Koliouskas Dimitrios, Karakatsanis Konstantinos (2008). Tc-99m HMPAO labeled white blood cell imaging in a child with eosinophilic lung disease. Clinical Nuclear Medicine. vol.33 no.1 p.38-40.
Moralidis Efstratios-Iordanis, Arsos Georgios, Papakonstantinou Eleni, Koliouskas Dimitrios, Karakatsanis Konstantinos (2008). I-123 metaiodobenzylguanidine (MIBG) in sympathetic denervation and reinnervation of salivary glands in a child with cervical neuroblastoma. Clinical Nuclear Medicine. vol.33 no.3 p.228-230.
Moralidis Efstratios-Iordanis, Arsos Georgios, Papakonstantinou Eleni, Badouraki M, Koliouskas Dimitrios, Karakatsanis Konstantinos (2008). 123I-Metaiodobenzylguanidine accumulation in a urinoma and cortex of an obstructed kidney after surgical resection of an abdominal neuroblastoma. Pediatric Radiology. vol.38 no.1 p.118-121.
Papakonstantinou Eleni, Kouri F.M, Karakiulakis George, Klagas I, Eickelberg O (2008). Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. The European Respiratory Journal. Published Version. vol.32 no.6 p.1504-1512.
Tzellos Th, Klagas I, Papakonstantinou Eleni, Vachtsevanos Konstantinos, Triaridis Stefanos, Kyrgidis Ath, Printza Athanasia, Zvintzou E, Karakiulakis George (2008). Differential expression of matrix metalloproteinases 2 and 9 in basal cell carcinoma photo-exposed and photo-protected skin. Review of Clinical Pharmacology and Pharmacokinetics International Edition. vol.22 no.2.
Vlachos G. D, Schulpis K. H, Papakonstantinou E, Papadakis M, Elefsiniotis I, Papassotiriou I, Antsaklis A (2008). Maternal chronic hepatitis B virus does not affect neonatal biotinidase activity. Acta Paediatr. vol.97 no.3 p.362-365.

2007

Karakiulakis George, Papakonstantinou Eleni, Aletras Alexis, Tamm M, Roth M (2007). Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling. The Journal of Biological Chemistry. Published Version. vol.282 no.2 p.908-915.
Mitropoulos D, Papakonstantinou Eleni, Aletras Alexis, Kalinderis Nikolaos, Zervas Anastasios, Chatzichristou Dimitrios, Karakiulakis George (2007). Terazosin modifies the content of glycosaminoglycans and the activity of matrix metalloproteinase 2 in the rat ventral prostate. European Urology. Published Version. vol.51 no.2 p.447-456.
Sidi V, Arsos Georgios, Papakonstantinou Eleni, Hatzipantelis Emmanouil, Fragandrea I, Gompakis Nikolaos, Koliouskas E (2007). Use of amifostine in the treatment of recurrent solid tumours in children. Hippokratia. vol.11 no.1 p.25-29.
Symeonidis C, Diza-Mataftsi Efdoxia, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Dimitrakos Stayros, Karakiulakis George (2007). Correlation of the extent and duration of rhegmatogenous retinal detachment with the expression of matrix metalloproteinases in the vitreous. Retina. Published Version. vol.27 no.9 p.1279-1285.
Symeonidis Chrysanthos, Diza-Mataftsi Evdoxia, Papakonstantinou Eleni, Soyliou-Symeonidou Effimia, Karakiulakis George, Dimitrakos Stayros (2007). Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment. Graefe's archive for Clinical and Experimental Ophthalmology. Published Version. vol.245 no.4 p.560-568.

2005

Papakonstantinou Eleni, Aletras Αlexis, Glass E, Tsogas Panagiotis, Dionyssopoulos A, Adjaye J, Fimmel S, Gouvousis P, Herwig R, Lehrach H, Zouboulis C.C, et al (2005). Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. The Journal of Investigative Dermatology. Published Version. vol.125 no.4 p.673-684.

2004

Papakonstantinou Eleni, Dionyssopoulos A, Aletras Alexis, Pesintzaki Chrisanthi, Minas Aristippos, Karakiulakis George (2004). Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis. Journal of the American Academy of Dermatology. Published Version. vol.51 no.4 p.526-533.

2003

Papakonstantinou Eleni, Aletras Alexis, Roth M, Tamm M, Karakiulakis George (2003). Hypoxia modulates the effects of transforming growth factor-beta isoforms on matrix-formation by primary human lung fibroblasts. Cytokine. Published Version. vol.24 no.1-2 p.25-35.
Papakonstantinou Eleni, Dionyssopoulos A, Pesintzaki Chrisanthi, Minas Aristippos, Karakiulakis George (2003). Expression of proteoglycans and glycosaminoglycans in angiofibroma and fibrous plaque skin lesions from patients with tuberous sclerosis. Archives of Dermatological Research. Published Version. vol.295 no.4 p.138-145.

2002

Papakonstantinou Eleni, Roth M, Tamm M, Eickelberg O, Perruchoud A.P, Karakiulakis George (2002). Hypoxia differentially enhances the effects of transforming growth factor-beta isoforms on the synthesis and secretion of glycosaminoglycans by human lung fibroblasts. The Journal of Pharmacology and Experimental Therapeutics. Published Version. vol.301 no.3 p.830-837.

2001

Karakiulakis George, Papakonstantinou Eleni, Roth M (2001). Assay for cell migration and invasion of vascular smooth muscle cells. Methods Molecular Medicine. Published Version. vol.52 p.163-169.
Papakonstantinou Eleni, Roth M, Karakiulakis George (2001). Isolation and characterization of glycosaminoglycans from human atheromatous vessels. Methods in Molecular Medicine. Published Version. vol.52 p.123-136.
Papakonstantinou Eleni, Roth M, Kokkas Vasileios, Papadopoulos Konstantinos, Karakiulakis George (2001). Losartan inhibits the angiotensin II-induced modifications on fibrinolysis and matrix deposition by primary human vascular smooth muscle cells. Journal of Cardiovascular Pharmacology. Published Version. vol.38 no.5.

2000

Goulas Antonios, Papakonstantinou Eleni, Karakiulakis George, Mirtsou-Fidani Vasiliki, Kalinderis Athanasios, Chatzichristou Dimitrios (2000). Tissue structure-specific distribution of glycosaminoglycans in the human penis. The International Journal of Biochemistry & Cell Biology. Published Version. vol.32 no.9 p.975-982.
Goulas Antonios, Chatzichristou Dimitrios, Karakiulakis George, Mirtsou-Fidani Vasiliki, Kalinderis A, Papakonstantinou Eleni (2000). Benign hyperplasia of the human prostate is associated with tissue enrichment in chondroitin sulphate of wide size distribution. The Prostate. Published Version. vol.44 no.2 p.104-110.
Papakonstantinou Eleni, Karakiulakis George, Tamm M, Perruchoud A.P, Roth M (2000). Hypoxia modifies the effect of PDGF on glycosaminoglycan synthesis by primary human lung cells. American Journal of Physiology. Lung cellular and molecular physiology. Published Version. vol.279 no.5 p.L825-L834.

1999

Papakonstantinou Eleni, Karakiulakis George, Roth M, Verghese-Nikolakaki S, Dawson M, Papadopoulos Orestis, Sklaviadis Theodoros (1999). Glycosaminoglycan analysis in brain stems from animals infected with the bovine spongiform encephalopathy agent. Archives of Biochemistry and Biophysics. Published Version. vol.370 no.2 p.250-257.

1998

Nauck M, Karakiulakis George, Perruchoud A.P, Papakonstantinou Eleni, Roth M (1998). Corticosteroids inhibit the expression of the vascular endothelial growth factor gene in human vascular smooth muscle cells. European Journal of Pharmacology. Published Version. vol.341 no.2-3 p.309-315.
Papakonstantinou Eleni, Roth M, Block L.H, Mirtsou-Fidani Vasiliki, Argiriadis P, Karakiulakis George (1998). The differential distribution of hyaluronic acid in the layers of human atheromatic aortas is associated with vascular smooth muscle cell proliferation and migration. Atherosclerosis. Published Version. vol.138 no.1 p.79-89.
Papakonstantinou Eleni, Karakiulakis George, Eickelberg O, Perruchoud AP, Block L.H, Roth M (1998). A 340 kDa hyaluronic acid secreted by human vascular smooth muscle cells regulates their proliferation and migration. Glycobiology. Published Version. vol.8 no.8 p.821-830.

1997

Karakiulakis George, Papanikolaou C, Jankovic S.M, Aletras A, Papakonstantinou Eleni, Vrettoy Eleni, Mirtsou-Fidani Vasiliki (1997). Increased type IV collagen-degrading activity in metastases originating from primary tumors of the human colon. Invasion & metastasis. Published Version. vol.17 no.3 p.158-168.

1993

Karakiulakis George, Papakonstantinou Eleni, Maragoudakis Michael E, Misevic GN (1993). Expression of type IV collagen-degrading activity during early embryonal development in the sea urchin and the arresting effects of collagen synthesis inhibitors on embryogenesis. Journal of Cellular Biochemistry. Published Version. vol.52 no.1 p.92-106.

----

Papakonstantinou Eleni, Karakiulakis George, Roth M, Block L.H. Platelet-derived growth factor stimulates the secretion of hyaluronic acid by proliferating human vascular smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America. Published Version. vol.92 no.21 p.9881-9885.
Papakonstantinou Eleni, Karakiulakis George, Aletras AJ, Misevic GN. A novel class of adhesion acidic glycans in sea urchin embryos. Isolation, characterization and immunological studies during early embryonal development. European journal of biochemistry. Published Version. vol.224 no.3 p.1067-1077.

Mis à jour: 2018-04-02