Curriculum Vitae

Dimitra Hadjipavlou-Litina

Professor Emeritus, School of Pharmacy

Personal Information

- 2310997627
hadjipav@pharm.auth.gr
http://www.pharm.auth.gr/el/faculty/47
Scopus ID35458544700
https://orcid.org/0000-0002-1844-350X
Γνωστικό Αντικείμενο:
Φαρμακευτική Χημεία με ιδιαίτερη ενασχόλιση στη σύνθεση, στο σχεδιασμό (ποσοτικές σχέσεις μοριακής δομής-δράσης) και στη φαρμακο
Επιστημονική Ειδίκευση:
- Χημεία
- Χρήση της πληροφορικής
- Φαρμακευτική

1979	πτυχίο Φαρμακευτικό Α.Π.Θ Greece

1989	ΔΔ Φαρμακευτικό Α.Π.Θ. Greece

Μετεκπαίδευση

Εκπαιδευτική άδεια 1992-1993 για εξειδίκευση σε θέματα computer-drug design

	SCHOOL OF PHARMACY
5	INTRODUCTION TO PHARMACEUTICAL SCIENCES & LEGISLATION
ΝΠ-03	HISTORY AND SUBJECTS IN PHARMACEUTICAL SCIENCES
ΝΠ18-44	Pharmaceutical Chemistry III
ΝΠ18-Δ1	Diploma Thesis 1/2
ΝΠ18-Δ2	Diploma Thesis 2/2
ΠΑ-1	Practical Training I

	POSTGRADUATE STUDIES PROGRAMME OF THE SCHOOL OF PHARMACY "INDUSTRIAL PHARMACY"
ΠΜΣΒΦ-001	Design, development and pharmacological evaluation of active drug molecules – Preformulation studies
ΠΜΣΒΦ-004	1st stage of elaboration of diploma thesis
ΠΜΣΒΦ-008	2nd stage of elaboration of diploma thesis
ΠΜΣΒΦ-010	3rd stage of elaboration of diploma thesis
ΠΜΣΒΦ-Μ1	Design, development and pharmacological evaluation of active drug molecules – Preformulation studies

	JOINT POSTGRADUATE PROGRAMME PHARMACEUTICAL LAW: LEGISLATION AND PRACTICE
ΦΔΑ1	INTRODUCTION TO THE CONCEPT OF MEDICINE

	Farmakochīmikī kai Farmakologikī Anáptyxī Farmakomoríōn
ΦΦΑΦ-01	Rational Drug Design

	SCHOOL OF PHARMACY
5	INTRODUCTION TO PHARMACEUTICAL SCIENCES & LEGISLATION
ΔΕ1	DIPLOMA THESIS 1/2
ΔΕ2	DIPLOMA THESIS 2/2
ΝΠ18-40	Pharmaceutical Chemistry II
ΝΠ18-Δ1	Diploma Thesis 1/2
ΝΠ18-Δ2	Diploma Thesis 2/2

	SCHOOL OF VETERINARY MEDICINE
4.7	Gender equality: social approach through biological sciences

	SCHOOL OF CHEMISTRY
ΕΦ935	Pharmaceutical Chemistry
Κ312	Pharmaceutical Chemistry

	JOINT POSTGRADUATE PROGRAMME PHARMACEUTICAL LAW: LEGISLATION AND PRACTICE
ΦΔΒ2	PRODUCTION AND DISTRIBUTION OF MEDICINES
ΦΔΒ5	POST-APPROVAL MONITORING OF THE SAFETY AND EFFECTIVENESS OF MEDICINES

	POSTGRADUATE STUDIES PROGRAMME OF THE SCHOOL OF PHARMACY "INDUSTRIAL PHARMACY"
ΠΜΣΒΦ-Μ1	Design, development and pharmacological evaluation of active drug molecules – Preformulation studies
ΠΜΣΒΦ-Μ10	2nd stage of elaboration of diploma thesis
ΠΜΣΒΦ-Μ9	1st stage of elaboration of diploma thesis

Theses Supervised

Student Theses within AUTh

In silico studies in small bioactive molecules acting against breastcancer inhibitors of aromatase
Pharmacochemical study of heterocyclic analogs of curcumin
In silico studies of druglikeness, ADMET inhibitors of LOX/COX. Application of quantitave models.
In silico studies of druglikeness and ADMET properties of antotaxin inhibitors. Prediction of possible multitarget activities
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In silico studies of drug-likeness and ADMET properties of antagonists/inhibitors of cytokines. Prediction of possible pleiotropic activities
In silico studies of Druglikeness and ADMET properties of Chalcones with anti-inflammatory activity - Prediction of possible multitarget activities
Cinamomic derivatives. Molecular hybridization and anti-inflammatory activity
In silico druglikeness study of hybrid coumarin molecules with biological interest
Pharmacochemical study of new compounds with pleiotropic anticoagulant action
Drug studies druglikeness- ADMET INHIBITORS OF COX / LOX. Application of quantitive models.

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Pharmacochemical study of curcumin/coumarin/enones/indandione hybrids with the propargyl group with potential biological activity in neurodegenerative diseases
In silico studies of kinase inhibitors. Investigation and evaluation of their pleiotropic bioactive profile.
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QSAR, ADMET in silico studies. Structure activity relationships for anticoagulant pharmacomolecules.
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Indan -1,3 - ones with biological activity
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Development, evaluation, Ιn silico studies of lipoxygenase/tyrosinase inhibitors for potential topical treatment of skin diseases
The pharmacy in the hospitals of Eastern Macedonia and Thrace from the early 20th century until today

Pharmacochemical study of serinoproteases inhibitors
Pharmacochemical study of compounds with anti-inflamatory and cancer activity
Pharmochemical study of ΑchΕ inhibitors
Pharmacochemical study of curcumin analogs
Pharmacochemical study of coumarin hybrids with possible biological interest
In silico druglikeness studies PDE5 inhibitors. Prediction of their possible multitarget activities

Pharmacovigilance in veterinary drugs - Legal framework and risks.
Pharmacochemical and pharmacotechnical studies of new derivatives with multitarget activity
Pharmacochemical study of bioactive cinammic hybrids
In silico study of carbonic anhydrase inhibitors with anti-inflammatory-anticancer activity
Evaluation study of the circulation and use of generic drugs in the Greek market. The views of health scientists and patients.

The history of the Greek pharmacy after the establishment of the Greek State

In silico studies of drug-likeness and ADMET properties of EGFR inhibitors. Prediction of possible pleiotropic activities
In silico studies of drug-likeness and ADMET properties of anti-epileptic/antiparkinsonic molecules with possible activity on Alzheimer disease
Pharmacochemical study of symmetrical analogues of curcumin
Pharmacochemical studies of Acetylcholinesterase inhibitors
Pharmacochemical Studies on Enzymes Inhibitors Implicated in Inflammation
Pharmacochemical study of hybrids analogs of curcumin
3D in silico studies of α-β unsaturated carboxylic and hydroxamic acids as PPARγ receptor agonists. Druglikeness
Synthesis of deferiprone hybrids for the treatment of glaucoma
Pharmacochemical study of Lipoic acid derivatives

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Synthesis, biological and in silico study of compounds with structural characteristics of naturally occurring molecules
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In silico studies of Drug-likeness and ADMET of Non-Steroidal Anti-Inflammatory Drugs, Antagonists of Interleukin and/or Cyclooxygenase-2 Inhibitors with potential action in Alzheimer's Disease

Druglikeness in silico studies of PDEs 3 and 4 inhibitors with activity on inflammation. Prediction of COX, LOX and AChE inhibitory activities. Molecular modelling studies
Heart vessels diseases - Scenaria of patient’s clinical cases

PHARMACOCHEMICAL AND PHARMACOTECHNICAL STUDY OF NEW COMPOUNDS WITH POSSIBLE ANTI-INFLAMMATORY ACTIVITY
Pharmacochemical development of new pyrrole derivatives & cinnamoyl hybrids
Pharmacochemical study of hybrids of biological active molecules

Design, synthesis and pharmacochemical study of hybrids with possiple activity on Alaheimer desease

Pharmacoepidemiological study of the use of psychotropic drugs (antidepressants, anxiolytics and hypnotics/sedatives) in Greece during the period 2015-2020
IN SILICO STUDIES OF DRUGLIKENESS, PHARMAKOKINETICS AND TOXICITY OF PHOSPHOLIPASE A2 INHIBITORS
In silico studies of druglikeness of COX inhibitors and prediction of AChE inhibition
STUDΙES ON DRUG-LIKENESS AND PHARMACOKINETIC PROPERTIES OF NEW ANTIEPILEPTIC STRUCTURES
In silico studies of ADMET properties of benzodiazepine derivatives. Studies on Druglikeness
METHYLOPHENIDATE ANALOGUES IN COCAINE ADDICTION: A POLYPHARMACOLOGICAL APPROACH

Synthesis and biological study of compounds with action on inflammatory factors. Formulation and control

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DEVELOPMENT, EVALUATION AND COMPARATIVE STUDY OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSAR) AND PHARMACOKINETIC CHARACTERISTICS OF NOVEL DUAL CYCLOXYGONASE & LIPOXYGONASE INHIBITORS
HYBRIDIZED AMIDES OF CINNAMIC ANALOGS WITH AMINO ACIDS, WITH POSSIBLE BIOLOGICAL INTEREST
Development, evaluation and comparative study of quantitative structure-activity relationships (QSAR) and pharmacokinetic characteristics of cyclooxygenase inhibitors 2 (COX-2)

Synthesis and pharmacochemical study of Hydrazones of Acetyl coumarins and their products with potential biological activity
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SYNTHESIS AND PHARMACOCHEMICAL STUDY OF ENONES WITH PONTETIONAL BIOLOGICAL ACTIVITY
DRUG-LIKENESS STUDY OF SEVERAL COMPOUNDS AS HMGR INHIBITORS
EVALUATION AND COMPARATIVE STUDY OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSAR) AND PHARMACOKINETIC CHARACTERISTICS OF NOVEL COUMARIN DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY

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«DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF COUMARIN HYBRID DERIVATIVES»

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Pharmacoepidemiological research in patients with Rheumatoid Arthritis
Correlation between treatment and upcoming cardiovascular diseases in patient with Rheumatoid Arthritis
DEVELOPMENT, EVALUATION AND COMPARATIVE STUDY OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSAR) AND PHARMACOKINETIC CHARACTERISTICS OF NOVEL CYTOKINE INHIBITORS
DEVELOPMENT, EVALUATION AND COMPARATIVE ANALYSIS OF QUANTITIVE STRACTURE-ACTIVITY RELATIONSHIP (QSAR) OF NEW XANTHINE OXIDASE INHIBITORS AND ANALYSIS OF THEIR PHARMAKOKINETIC PARAMETERS
Design and Synthesis of coumarin derivatives with possible biological activity
SYNTHESIS AND PHARMACOCHEMICAL STUDY OF 4-HYDROXY-COUMARIN ENONE HYBRIDS WITH BIOLOGICAL ACTIVITY

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DEVELOPMENT, EVALUATION AND COMPERATIVE STUDY OF QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSAR) AND PHARMACOKINETIC CHARACTERISTICS OF NOVEL CHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE
Computing and comperative QSAR study on caffeic acid hybrids with biologicaL interest.
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Pharmacochemical Study of Heterocyclic Derivatives
Design, Synthesis and Pharmacochemical Evaluation of Novel Bioactive Cinnamoyl Derivatives

Pharmacochemical evaluation of enonic moiety: design, synthesis, biological study and theoretical determination og physicochemical properties.

Development, analysis and comparative study of HDACs inhibitors through 2D – QSAR methodology
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COPPER (II) AND Zn(II) COMPLEXES WITH 2,2'-BIPYRIDINE AND 4,4' - tBu-2,2'-BIPYRIDINE. HETEROLEPTIC COMPLEXES WITH 2-,3- AND 4-SUBSTITUTED AMINOBENZOIC ACIDS. SYNTHESIS AND STUDY OF THE STRUCTURE AND PUTATIVE BIOLOGICAL ACTIVITY.

SYNTHESIS AND PHARMACOCHEMICAL STUDY OF 4-HYDROXY-COUMARIN ENONE HYBRIDS WITH BIOLOGICAL ACTIVITY
USING ENONE TEMPLATE FOR THE SYNTHESIS OF CYCLOHEXENONES WITH BIOLOGICAL INTEREST

DESIGN AND SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS USING THE CINAMMIC / PROPENONES SCAFFOLDS.
DESIGN, SYNTHESIS AND PHARMACOCHEMICAL STUDY OF NOVEL BENZAMIDES WITH BIOLOGICAL INTEREST

QUANTITATIVE STRUCTURE- ACTIVITY RELATIONSHIPS OF BENZODIAZEPINES WITH ANTICANCER ACTIVITY. USE OF THE RESULTS IN THE DESIGN OF MULTIFUNCTIONAL AGENTS. EXAMPLE OF PDES INHIBITORS.
DEVELOPMENT, ANALYSIS AND COMPARATIVE STUDY OF PDES INHIBITORS THROUGH 2-D-QSAR METHOLOGY
SYNTHESIS OF HYBRID COUMARIN DERIVATIVES WITH BIOLOGICAL ACTIVITY
SYNTHESIS OF BIOLOGICAL ACTIVΕ CHLOROETHERS AND ETHYLENEDIAMINES CONTAINING AN ENONE GROUP

DESIGN, SYNTHESIS AND PHARMACOCHEMICAL STUDY OF NEW HYBRID CINNAMIC ACID DERIVATIVES WITH POSSIBLE BIOLOGICAL ACTIVITY

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Theses outside AUTh

Σ. ΚΩΣΤΟΥΔΗΣ. Αξιοποίηση του αζωμεθινικού δεσμού στο σχεδιασμό και τη σύνθεση θειαζολικών παραγώγων ως πιθανών αναστολέων μεταλλοενζύμων, ΕΚΠΑ.
Θ.ΛΙΑΡΓΚΟΒΑ. Σχεδιασμός, Σύνθεση και βιολογική αξιολόγηση ενονικών παραγώγων, ΕΚΠΑ.

Ε.ΜΠΕΡΜΠΕΡΟΓΛΟΥ. Σύνθεση, φαρμακοχημική μελέτη και ποσοτικές σχέσεις δομής δράσης νέων κυκλοεξενονών και οξαζολονών πιθανή ανασταλτική δράση στη τυροσινάση και σε παράγοντες της φλεγμονής., ΕΚΠΑ.

Ο.ΚΟΥΖΗ. Παράγωγα 1,3-ινδανδιόνης με πιθανή αντιφλεγμονώδη και αντιπρωτεολυτική δράση. Συνθεση, φαρμακοχημική μελέτη και ποσοτικές σχέσεις δομής-δράσης, ΕΚΠΑ.

Μ.ΓΙΑΚΟΥΜΑΚΟΥ. ΦΑΡΜΑΚΟΧΗΜΙΚΗ ΜΕΛΕΤΗ ΝΕΩΝ ΧΑΛΚΟΝΩΝ ΜΕ ΠΙΘΑΝΗ ΑΝΤΙΦΛΕΓΜΟΝΩΔΗ ΔΡΑΣΗ, ΕΚΠΑ.

Θ.ΦΕΙΔΑΝΤΣΗΣ. Σύνθεση και φαρμακοχημική μελέτη νέων αντιφλεγμονωδών ενώσεων με πιθανή ανασταλτική δράση επί της λιποξυγονάσης ή/και της κυκλοξυγονάσης, ποσοτικές σχέσεις δομής-δράσης., ΕΚΠΑ.

Α.Μιχαηλίδου. ΣΥΝΘΕΣΗ ΚΑΙ ΒΙΟΛΟΓΙΚΟΣ ΕΛΕΓΧΟΣ ΝΕΩΝ ΕΝΩΣΕΩΝ ΜΕ ΠΙΘΑΝΗ ΑΝΤΙΦΛΕΓΜΟΝΩΔΗ ΔΡΑΣΗ.ΕΞΑΓΩΓΗ ΠΟΣΟΤΙΚΩΝ ΣΧΕΣΕΩΝ ΔΟΜΗΣ-ΔΡΑΣΗΣ QSAR ΓΙΑ ΕΝΩΣΕΙΣ ΜΕ ΑΝΤΙΦΛΕΓΜΟΝΩΔΗ ΔΡΑΣΗ (Ανεύρεση, εξέταση, ανάλυση δεδομένων, Ανάλυση και συγκριτικό QSAR, Αξιοποίηση αποτελεσμάτων), ΕΚΠΑ.

Ε.ΠΟΝΤΙΚΗ. Προσπάθεια εξαγωγής και μελέτη Ποσοτικών Σχέσεων Δομής - Δράσης (QSAR) αναστολέων της λιποξυγονάσης: ανεύρεση, εξέταση, ανάλυση δεδομένων. Συγκριτικό QSAR. Aξιοποίηση των αποτελεσμάτων: Σύνθεση - Βιολογικός Ελεγχος νέων ενώσεων, ΕΚΠΑ.

ΤΑΣΙΟΥ Ν.. Προσπάθεια εξαγωγής ποσοτικών σχέσεων δομής-δράσης για μόρια που εκδηλώνουν αντιοξειδωτική δράση: ανεύρεση, εξέταση, ανάλυση δεδομένων. Συγκριτικό QSAR. Αξιοποίηση των αποτελεσμάτων, ΕΚΠΑ.

Administrative Work

Τμήματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
6	2013	2015	Head, OMEA
9	2013	2015	Director, ΣΕΜΣ πρόγραμμα Μεταπτυχιακών Σπουδών
7	2012	2015	Vice Head, Τμήμα φαρμακευτικής
4	2012		Head, ΕCTs συντονιστής
2	2011	2013	Member, επιτροπή προπτυχιακού προγράμματος Σπουδών
8	2011	2013	Director, ΣΕΜΣ πρόγραμμα Μεταπτυχιακών Σπουδών
5	2011	2012	Head, Επιτροπή ιστοσελίδας τμήματος
3	2010	2013	Head, Επιτροπή οδηγού Σπουδών
1	2009	2013	Head, OMEA

Ιδρύματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
8	2015		Member, επιτροπή ΚΕΔΕΚ
7	2012	2014	Member, επιτροπή ερευνών
1	2011	2012	Member, Επιτροπή Εκπαιδευτικής Πολιτικής
4	2011	2012	Member, Κεντρική επιτροπή κατατακτηρίων εξετάσεων πτυχιούχωνΑΕΙ & ΤΕΙ
3	2010	2013	Member, επιτροπή ερευνών
6	2010	2013	Member, Επιτροπή ΔΕοντολογίας της έρευνας
2	2010	2011	Member, επιτροπή εκπαιδευτικής πολιτικής
5	2010	2011	Member, Κεντρική Επιτροπή Εξετάσεων ΠτυχιούχωνΑΕΙ & ΤΕΙ

Άλλο
#	Από	Έως	Θέση Περιγραφή
2	2012	2016	μέλος, επιτροπή παραλαβής
1	2002	2012	μέλος, επιτροπή παραλαβής

Research Projects

Coordinator
2026–2026	Results' evaluation of hybrids with biological activity
2021–2024	Rethinking Equality and Scientific Excellence Together
2019–2023	Scholarships Hellenic Petroleum SA
2019–2019	Covering the needs of the Secreteriat of the School of Pharmacy
2017–2017	Financing for the School of Pharmacy AUTH from the Greek Ministry of Education, Research & Religious Affairs 2017
2017–2017	Financing for the “Master program of the school of Pharmacy from the Public Investments Program Greek Ministry of Education, Research & Religious Affairs 2017
2013–2014	Design, synthesis and biological study of hybrids cinammmomic acid deriratives with multiple biologicl targets
2012–2016	Studend internship of the school of Pharmacy
1998–1999	Σύνθεση φουροκουμαρινών και μελέτη των βιολογικών τους ιδιοτήτων.

Participant
2021–2026	“Pharmaceutical Law: Legislation and Practice”
2020–2023	Synthesis of fused pyranoquinolinone derivatives with possible biological interest
2018–2022	Greek Aromatic and medicinal plants exploitation
2014–2014	Knowledge updating of higher education institution graduates in modern applications in biosciences
2012–2013
2010–2013
2008–2010	Analysis of essential oils of aromatic and pharmaceutical plants of prefecture of Florina- Study of antioxidant and anti-inflammatory avtivity of plants
2006–2026	-
2006–2008	Exploitation of pharmaceutical species with economic interest of genus Thymus (Thyme)
2003–2008	Reconstuction of Undergraduate Studies Programme of the Pharmaceutical Dept. of Auth
2002–2008	Pharmaceutical Science
2001–2017
1998–2019	Πληρωμή μέλους ΔΕΠ -Βασιλικιώτης Γ.
1998–2000	Παραγωγή και έλεγχος φαρμακευτικών ενώσεων.
1997–2023	Πληρωμή μελών ΔΕΠ ΑΠΘ για αξιολογήσεις και λοιπές υπηρεσίες - Ν. 2530/97 (ΓΓΕΤ )

Non ELKE AUTh

1-2-2013-31-1-2014Σχεδιασμός σύνθεση και βιολογική μελέτη υβριδικών κιναμμωμικών παραγώγων με πολλαπλούς βιολογικούς στόχους

Publications

Lazari Diamanto, Marinaki N., Krigkas Nikolaos, Hadjipavlou-Litina Dimitra . (2012) . Composition and antioxidant activity of Stachys ionica Halácsy (Lamiaceae) essential oil . Book of abstracts of the 6th European Botanic Gardens Congress . 6th European Botanic Gardens Congress . (Eds):Cook, C.M., Maloupa, Eleni and Mylona PH. . Chios Island-Greece . Chios Island, Greece . p.104

Lazari Diamanto, Krigkas Nikolaos, Hadjipavlou-Litina Dimitra . (2010) . Composition and antioxidant activity of Achillea coarctata and A. Grandıfolıa essential oils (Asteraceae) . Book of Abstracts of the Phytochemical Society of Europe (PSE) International Symposium on ”Terpenes: Application, Activity and Analysis” . Phytochemical Society of Europe (PSE) International Symposium on ”Terpenes: Application, Activity and Analysis” . Istanbul, Turkey . Istanbul, Turkey . p.57

Distinctions

Updated: 2026-05-21

Quality Assurance Unit (MODIP)Aristotle University of Thessaloniki

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Curriculum Vitae

Dimitra Hadjipavlou-Litina

Προπτυχιακές Σπουδές

Διδακτορικό Δίπλωμα

Μετεκπαίδευση

Courses of Winter semester of 2025–26 academic year

Courses of Spring semester of 2025–26 academic year

Student Theses within AUTh

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Theses outside AUTh

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2011–2012

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Non ELKE AUTh

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Quality Assurance Unit (MODIP)
Aristotle University of Thessaloniki