Curriculum Vitae

Vasiliki Sarli

Assistant Professor, School of Chemistry

Personal Information

- 2310997840
sarli@chem.auth.gr
http://users.auth.gr/~sarli/
Scopus ID9233713700
Γνωστικό Αντικείμενο:
Οργανική Χημεία με Έμφαση στη Συνθετική Οργανική Χημεία
Επιστημονική Ειδίκευση: Χημεία

Education

Προπτυχιακές Σπουδές

1999	Πτυχίο Χημείας Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης Greece Οργανική Χημεία

Διδακτορικό Δίπλωμα

2004	PhD Χημείας Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης Greece Οργανική Χημεία

Μετεκπαίδευση

2004-2008 Universität Leipzig, Γερμανία

Μεταδιδακτορική έρευνα στο εργαστήριο του καθηγητή Α. Γιάννη στο πεδίο της οργανικής σύνθεσης και χημικής βιολογίας

2005-2007 EMBL ερευνήτρια επισκέπτης, Heidelberg, Γερμανία

(Marie Curie, Spindle Dynamics research network)

Course Work

Courses of Winter semester of 2018–19 academic year

	TMĪMA CΗĪMEIAS
48
Κ313	Bioorganic Chemistry
ΥΕ16	Organic Chemistry Laboratory II
ΥΝ16	Organic Chemistry III
ΥΧΟ321	Organic Chemistry III

Courses of Spring semester of 2018–19 academic year

	TMĪMA CΗĪMEIAS
48
ΕΧΟ428	Bioorganic Chemistry
Κ307	Introduction to Natural Products and Introduction to Bioorganic Chemistry
Κ313	Bioorganic Chemistry
Υ12	Organic Chemistry III
ΥΕ16	Organic Chemistry Laboratory II
ΥΝ16	Organic Chemistry III

Theses Supervised

Student Theses within AUTh

In progress

Voura Maria. "Σχεδιασμός και σύνθεση αναστολέων των κινασών MARK".
Leonidis Georgios.
Sflakidou Eleni.
, Kofokotsiou Iro. Σύνθεση βιοδραστικών ενώσεων με αντικαρκινική δράση (1)
Thysiadis Savvas. "Σύνθεση βιοδραστικών μορίων ως ρυθμιστών πρωτεϊνών στη μελέτη βιολογικών διεργασιών".
, Papadopoulou Athina. Σύνθεση βιοδραστικών ενώσεων με αντικαρκινική δράση (2)
Grammatikopoulou Margarita. «Σύνθεση αλκαλοειδών πυρρολίου με πιθανή αντικαρκινική δράση».
Chatzisideri Theodora. "Σύνθεση πεπτιδικών παραγώγων που στοχεύουν καρκινικά κύτταρα".

2017–2018

Grammatikopoulou Margarita. "Μελέτη σύνθεσης παραγώγων των Μαρινεοσινών και στερεοειδικών λακτονών".
Rantzios Konstantinos. Σύνθεση παραγώγων στεροειδών με 2-αμινο-3H-πυρρολο[2,3-d]πυριμιδιν-4(7H)-όνες
Fragkoulidou Sousanna. "Σύνθεση βενζυλικών παραγώγων της 2-μεθυλακριδόνης"
Parasidou Eleftheria. "Σύνθεση παραγώγων της 2-μεθυλακριδόνης για την αναστολή της κινάσης MARK4"
Siokatas Christos. "Σύνθεση παραγώγων στεροειδών με 1H-πυραζολο[3,4-d]πυριμιδιν-4-αμίνες"
Pappas Georgios. Μελέτες για τη σύνθεση διαμορφωμερώς περιορισμένων αμινοξέων

2016–2017

Voura Maria. "Σύνθεση ενός στεροειδικού παραγώγου της γεμσιταμπίνης και ακριδονών ως αναστολέων της κινάσης MARK".
Almpanakis Konstantinos. "ΣΥΝΘΕΣΗ ΤΡΙΑΖΟΛΟΘΕΙΑΔΙΑΖΟΛΙΩΝ ΚΑΙ ΠΑΡΑΓΩΓΩΝ ΣΤΕΡΟΕΙΔΩΝ ΜΕ ΠΙΘΑΝΗ ΑΝΤΙΚΑΡΚΙΝΙΚΗ ΔΡΑΣΗ".

2015–2016

Bousis Spyridon. "Σύνθεση παραγώγων της γαλλοκυανίνης".

2014–2015

Geromichalou Eleni. "Σύνθεση υβριδικών παραγώγων μονο- και διλακταμικών στεροειδών με αλκυλιωτικούς παράγοντες ή αντιμεταβολιτές".

2013–2014

Thysiadis Savvas. "Προσπάθειες σύνθεσης των φυσικών προϊόντων Μαρινεοσίνη Α και Β".

2012–2013

CΗatzībaloglou Anthoula. "Προσπάθειες σύνθεσης των φυσικών προϊόντων φαιοσφαιριδίων Α και Β και ανάλογων μορίων".

2010–2011

Lymperis Emmanouil. "Προσπάθειες σύνθεσης των φυσικών προϊόντων μαρινεοσίνη Α και Β".

Administrative Work

Τμήματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
1	2009	2015	Member, Υπεύθυνη Διαχείρισης Εργαστηριακών Αποβλήτων του Εργαστηρίου Οργανικής Χημείας

Ιδρύματος
#	Από	Έως	Θέση Όργανο / Επιτροπή
1	2008	2015	Member, Βιβλιοθήκης

Research Projects

2018–2019	Οργάνωση και λειτουργία του ΕΚΜΜ
2017–2019	Σύστημα οργανωμένης αποθήκευσης και διαχείρησης χημικών ενώσεων του Ελληνικού Κέντρου Μικρομορίων (ΕΚΜΜ)
2017–2019	Αναβάθμιση της υπάρχουσας υποδομής του ΕΚΜΜ
2014–2015	Ανάπτυξη μικρών μορίων τροποποιητών του σήματος Wnt για τη θεραπεία της νόσου Alzheimer
2013–2014	ΔΡΑΣΗ Γ:Ενίσχυση ερευνητικής δραστηριότητας βασικής έρευνας: Σύνθεση και βιολογική μελέτη αναστολέων του σήματος JAK/STAT3

Publications

2041

Book Chapter

Sarli Vasiliki (2041). Transition-Metal-Catalyzed Asymmetric C–C Cross Couplings. Stereoselective Synthesis of Drugs and Natural Products. publisher Andrushko, V.

2017

Journal Article

Chatzisideri T, Thysiadis S, Katsamakas S, Dalezis P, Sigala I, Lazarides T, Nikolakaki Eleni, Trafalis D, Gederaas OA, Lindgren M, Sarli Vasiliki (2017). Synthesis and biological evaluation of a Platinum(II)-c(RGDyK) conjugate for integrin-targeted photodynamic therapy. European Journal of Medicinal Chemistry. vol.141 p.221-231.
Demertzidou VP, Pappa S, Sarli Vasiliki, Zografos Alexandros (2017). Regioselective Ene-Type Allylic Chlorination of Electron-Rich Alkenes by Activated DMSO. The Journal of Organic Chemistry. vol.82 no.16 p.8710–8715.
Sigala I, Ganidis G, Thysiadis S, Zografos Alexandros, Giannakouros Thomas, Sarli Vasiliki, Nikolakaki Eleni (2017). Lynamicin D an Antimicrobial Natural Product Affects Splicing by Inducing the Expression of SR Protein Kinase 1. Bioorganic and Medicinal Chemistry. vol. 25 no.5 p. 1622–1629.
Thysiadis S, Katsamakas S, Dalezis P, Chatzisideri T, Trafalis D, Sarli Vasiliki (2017). Novel c(RGDyK)-based Conjugates of POPAM and 5-FU for Integrin-Targeted Cancer Therapy. Future Medical Chemistry. vol.9 no.18 p.2181-2196.
Trafalis D T, Polonifi A, Dalezis P, Nikoleousakos N, Katsamakas S, Sarli Vasiliki (2017). Targeting on Poly (ADP-ribose) polymerase activity with DNA damaging hybrid lactam-steroid alkylators in wild type and BRCA1 mutated ovarian cancer cells. Chemical Biology and Drug Design.
Tsovaltzi E, Malamidou-Xenikaki Elisavet, Dalezis P, Chatzidimitriou Antonios, Lazaridis Theodoros, Trafalis D, Sarli Vasiliki (2017). Synthesis and analysis of the anticancer activity of Ru( ii ) complexes incorporating 2-hydroxymethylidene-indene-1,3-dione ligands. New Journal of Chemistry. vol.41 no.18 p.10438-10446.

2016

Journal Article

Charitos G, Trafalis DT, Dalezis P, Potamitis C, Sarli Vasiliki, Zoumpoulakis P, Camoutsis C (2016). Synthesis and anticancer activity of novel 3,6-disubstituted 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives. Arabian Journal of Chemistry.
Katsamakas S, Zografos A.L, Sarli Vasiliki (2016). Advances of phenoxazines: Synthesis, reactivity and their medicinal applications. Current Medicinal Chemistry.
Mpousis S, Thysiadis S, Avramidis N, Katsamakas S, Efthimiopoulos S, Sarli Vasiliki (2016). Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies. European Journal of Medicinal Chemistry. Vol. 108 p. 28–38.
Thysiadis S, Mpousis S, Avramidis N, Katsamakas S, Balomenos A, Remelli R, Efthimiopoulos S, Sarli Vasiliki (2016). Discovery of novel phenoxazinone derivatives as DKK1/LRP6 interaction inhibitors: Synthesis, biological evaluation and structure-activity relationships. Bioorganic and Medicinal Chemistry. Vol. 24 no.5 p. 1014–1022.
Trafalis D, Geromichalou E, Dalezis P, Nikoleousakos N, Sarli Vasiliki (2016). Synthesis and evaluation of new steroidal lactam conjugates with aniline mustards as potential antileukemic therapeutics. Steroids. vol. 115 p. 1-8.

2015

Journal Article

Grammatikopoulou M, Thysiadis S, Sarli Vasiliki (2015). Gold-catalyzed spiro-N,O-ketal synthesis. Organic & Biomolecular Chemistry. vol.13 p.1169.

Conference Announcement

Mpousis S, Thysiadis S, Avramidis N, Eythimiopoulos S, Sarli Vasiliki (2015). Synthesis of Gallocyanine derivatives as a new glass of Dickkopf inhibitors. 12 Συνέδριο Ελλάδας-Κύπρου. Θεσσαλονίκη.

2014

Journal Article

Chatzimpaloglou Ananias, Kolosov M, Eckols TK, Tweardy DJ, Sarli Vasiliki (2014). Synthetic and biological studies of phaeosphaerides. J Org Chem. p.4043.

Conference Announcement

Τσιτουρούδη Φ, Πουλχαρίδης Δ, Σαρλή Βασιλική, Ανδριώτης ΕΓ, Χολή-Παπαδοπούλου Θεοδώρα, Αχιλιάς Δημήτριος (2014). Πολυμερικά υλικά «εξοπλισμένα» με ειδικά οργανικά μόρια προωθούν την διαφοροποίηση στελεχιαίων κυττάρων σε οστεοβλάστες. 9η Διημερίδα ΕΕΒ. Αθήνα.

2012

Journal Article

Chatzimpaloglou Ananias, Yavropoulou MP, Rooij KE, Biedermann R, Mueller U, Kaskel S, Sarli Vasiliki (2012). Total synthesis and biological activity of the proposed structure of phaeosphaeride A. Journal of Organic Chemistry. vol.77 p.9659.

2011

Journal Article

Massen Z. S, Sarli Vasiliki, Koutouli-Argyropoulou Evdoxia, Gallos Ioannis (2011). Synthesis of C-glycosylated amino acids by hetero-Diels-Alder addition of ethyl 2-nitrosoacrylate to exo-glycals. Carbohydrate research. vol.346 no.2 p.230-237.
Massen Z. S, Koutouli-Argyropoulou Evdoxia, Sarli Vasiliki, Gallos Ioannis (2011). Synthesis of a protected trihydroxyindolizidine 3-carboxylate via a hetero-Diels-Alder addition of ethyl 2-nitrosoacrylate to a d-ribose-derived exo-glycal. Carbohydrate Research. vol.346 no.4 p.508-511.
Tcherniuk S, Deshayes S, Sarli V. C, Divita G, Abrieu A (2011). UA62784 is a cytotoxic inhibitor of microtubules, not CENP-E. Chem Biol. vol.18 p.631.
Voultsiadou A, Sarli V. C (2011). Recent Advances of Kinesin Motor Inhibitors and their Clinical Progress. Rev.Recent Clin.Trials. vol.6 p.271.

Conference Announcement

Χατζημπαλόγλου Ανανίας, Σαρλή Βασιλική (2011). Σύνθεση και βιολογική μελέτη των φυσικών προιόντων Phaeosphaerides. 21ο Πανελλήνιο Συνέδριο Χημείας. Κέντρο Διάδοσης Ερευνητικών Αποτελεσμάτων Α.Π.Θ., Θεσσαλονίκη.

Translation

Σαρλή Βασιλική (2011). Ετεροκυκλική Χημεία σε μια ματιά. Παρισιάνος.

2010

Journal Article

Kanakis A, Sarli Vasiliki (2010). Total Synthesis of (±)-Marinopyrrole A via Copper-Mediated N-Arylation. Organic Letters. vol.12 no.21 p.4872.
Kanakis A, Sarli V. C (2010). Total Synthesis of (±)-Marinopyrrole A via Copper-Mediated N-Arylation. Org.Lett. vol.12 p.4872.

Conference Announcement

Sarli Vasiliki (2010). Total synthesis of the proposed structure of Phaeosphaeride A. 14th Hellenic Symposium on Medicinal Chemistry. Thessaloniki, Greece.

2009

Journal Article

Buttner A, Seifert K, Cottin T, Sarli Vasiliki, Tsagkaroudaki L, Scholz S, Giannis A (2009). Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway. Bioorganic and Medicinal Chemistry. vol.17 p.4943.
Buttner S. K, Cottin T, Sarli V. C, Tzagkaroulaki L, Scholz S, Giannis A (2009). Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway. Bioorg Med Chem. vol.17 p.4943.
Giannis A, Heretsch P, Sarli Vasiliki, Stößel A (2009). Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach. Angewande Chemie, International Edition. vol.48 no.42 p.7911.
Giannis A, Heretsch P, Sarli V. C, Stößel A (2009). Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach. Angew Chem Int Ed Engl. vol.48 p.7911.

2008

Journal Article

Mann S, Sarli Vasiliki, Giannis A (2008). Convenient Synthesis of Functionalized Furans. Synthesis. p.2617.
Mann S, Sarli V. C, Giannis A (2008). “Convenient Synthesis of Functionalized Furans”. Synthesis. Synthesis. p.2617.
Sarli V. C, Giannis A (2008). Basic Principles and Clinical Implications, CCR Molecular Pathways. Targeting KSP. Clin Cancer Res. vol.14 p.7583.
Tsanakopoulou M, Cottin T, Büttner A, Sarli Vasiliki, Malamidou-Xenikaki Elisavet, Spyroudis Spyros, Giannis A (2008). Indeno[1,2-d]pyrido[1,2-a]pyrimidines: A New Class of Receptor Tyrosine Kinase Inhibitors. ChemMedChem. vol.3 p.429.
Tsanakopoulou M, Cottin T, Büttner A, Sarli V. C, Malamidou-Xenikaki E, Spyroudis S, Giannis A (2008). Indeno[1,2-d]pyrido[1,2-a]pyrimidines: A new class of receptor tyrosine kinase inhibitors. ChemMedChem. vol.3 no.3 p.429-433.

Book Chapter

Giannis A, Sarli Vasiliki (2008). Kinesin motor inhibitors as effective anti-cancer drugs. Checkpoint Responses and Cancer Therapy.

2007

Journal Article

Muller C, Gross D, Sarli V. C, Gartner M, Giannis A, Bernhardt G, Buschauer A (2007). Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells. Cancer Chemother.Pharmacol. vol.59 p.157.
Sarli Vasiliki, Giannis A (2007). Selective inhibition of CBP/p300 HAT. Chemistry and Biology. vol.14 no.6 p.605-606.

2006

Journal Article

Argyropoulos N. G, Sarli V. C, Gdaniec M (2006). Synthesis of pyrrolizidine derivatives by 1,3-dipolar cycloaddition reactions of chiral five-membered cyclic azomethine ylides. European Journal of Organic Chemistry. no.16 p.3738-3745.
Argyropoulos Nikolaos, Sarli Vasiliki, Gdaniec M (2006). Synthesis of Pyrrolizidine Derivatives by 1,3-Dipolar Cycloaddition Reactions of Chiral Five-Membered Cyclic Azomethine Ylides. Eur. J. Org. Chem. p.3738.
Liu M, Aneja R, Liu C, Sun L, Gao J, Wang H, Dong J-T, Sarli Vasiliki, Giannis A, Joshi HC, Zhou J (2006). Inhibition of the mitotic kinesin Eg5 upregulates Hsp70 through the PI3K/Akt pathway in multiple myeloma cells. J. Biol. Chem. vol.281 p.18090.
Liu M, Aneja R, Liu C, Sun L, Gao J, Wang H, Dong J.-T, Sarli V. C, Giannis A, Joshi H. C, Zhou J (2006). Inhibition of the mitotic kinesin Eg5 upregulates Hsp70 through the PI3K/Akt pathway in multiple myeloma cells. J.Biol.Chem. vol.281 p.18090.
Sarli V. C, Giannis A (2006). Inhibitors of Mitotic Kinesins: Next Generation Antimitotics. Chem.Med.Chem. vol.1 p.293.

2005

Journal Article

Gallos Ioannis, Sarli Vasiliki, Massen YS, Varvogli AC, Papadoyanni CZ, Papaspyrou SD, Argyropoulos Nikolaos (2005). A new strategy for the stereoselective synthesis of unnatural α-amino acids. Tetrahedron. vol.61 p.565.
Gallos J. K, Sarli V. C, Massen Z. S, Varvogli A. C, Papadoyanni C. Z, Papaspyrou S. D, Argyropoulos N. G (2005). A new strategy for the stereoselective synthesis of unnatural α-amino acids. Tetrahedron. vol.61 no.3 p.565-574.
Sarli V. C, Huemmer S, Sunder-Plassmann N, Mayer T. U, Giannis A (2005). Synthesis and Biological Evaluation of Novel Eg5 Inhibitors. ChemBioChem. vol.6 p.2005.
Sunder-Plassmann N, Sarli V. C, Gartner M, Utz M, Seiler J, Huemmer S, Mayer T. U, Surrey T, Giannis A (2005). Synthesis and biological evaluation of new tetrahydro-β-carbolines as inhibitors of the mitotic kinesin Eg5’. Biοorg.Med.Chem. vol.13 p.6094.

2004

Journal Article

Argyropoulos N. G, Sarli V. C (2004). Synthesis of a branched chain aza-C-disaccharide via the cycloaddition of a chiral nitrone to an alkene, both sugar derivatives. Tetrahedron letters. vol.45 no.22 p.4237-4240.
Argyropoulos Nikolaos, Sarli Vasiliki (2004). Synthesis of a branched chain aza-C-disaccharide via the cycloaddition of a chiral nitrone to an alkene, both sugar derivatives. Tetrahedron Lett. vol.45 p.4237.

2003

Journal Article

Gallos Ioannis, Sarli Vasiliki, Varvoglis Anastasios, Papadogianni CZ, Papaspyrou SD, Argyropoulos Nikolaos (2003). The Hetero-Diels-Alder Addition of Ethyl 2-Nitrosoacrylate to Electron Rich Alkenes as a Route to Unnatural α-Amino Acids. Tetrahedron Lett. vol.44 p.3905.
Gallos J. K, Sarli V. C, Varvogli A. C, Papadoyanni C. Z, Papaspyrou S. D, Argyropoulos N. G (2003). The hetero-Diels-Alder addition of ethyl 2-nitrosoacrylate to electron-rich alkenes as a route to unnatural α-amino acids. Tetrahedron letters. vol.44 no.20 p.3905-3909.

2002

Journal Article

Gallos Ioannis, Sarli Vasiliki, Stathakis CI, Koftis TV, Nachmia VR, Coutouli-Argyropoulou E (2002). Hetero-Diels-Alder additions to pent-4-enofuranosides: concise synthesis of hydroxylated pyrrolizidines. Tetrahedron. vol.58 p.9351.

2000

Journal Article

Gallos Ioannis, Sarli Vasiliki, Koftis TV, Coutouli-Argyropoulou E (2000). A New Entry to Hydroxylated Pyrrolizidines. Tetrahedron Lett. vol.41 p.4819.

1998

Conference Announcement

Gallos Ioannis, Sarli Vasiliki, Koftis TV (1998). A novel route to pyrrolizidine alkaloids. 1st International Conference of the chemical Societies of the South-East European Countries. Chalkidiki, Greece.

Conference Announcement

Giannis A, Sarli Vasiliki (-). Development of new Eg5 inhibitors’. 1st Workshop of the Marie Curie Research Training Network.
Mpousis S, Thysiadis S, Avramidis Nikolaos, Eythimiopoulos S, Sarli Vasiliki (-). SYNTHESIS OF GALLOCYANINE DERIVATIVES AS A NEW CLASS OF DICKKOPF INHIBITORS. 12 Συνέδριο Ελλάδας-Κύπρου.
Sarli Vasiliki (-). The Chemical Biology of Stat3 Signaling. Eurochems Organic Division, Young Investigator Workshop associated with ESOC 2009.
Sarli Vasiliki, Giannis A (-). Antiproliferative Effect of a Selective Eg5 Inhibitor against Human Glioblastoma Cells. 2nd Workshop of the Marie Curie Research Training Network, Spindle dynamics.

----

Conference Announcement

Argyropoulos Nikolaos, Sarli Vasiliki. Pyrrolizidine synthesis via 1,3-dipolar cycloaddition reactions of chiral nonstabilized azomethine ylides. 2nd International Conference of the chemical Societies of the South-East European Countries.
Gallos Ioannis, Papadoyanni CZ, Sarli Vasiliki, Argyropoulos Nikolaos. A new method for the syntesis of unnatural a-amino acids. 2nd International Conference of the chemical Societies of the South-East European Countries.
Giannis A, Sarli Vasiliki. Natural products as a source for discovery, synthesis and application of new pharmaceuticals. COST D28 training school.

Updated: 2018-10-04

Quality Assurance Unit (MODIP)Aristotle University of Thessaloniki

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Curriculum Vitae

Vasiliki Sarli

Προπτυχιακές Σπουδές

Διδακτορικό Δίπλωμα

Μετεκπαίδευση

Courses of Winter semester of 2018–19 academic year

Courses of Spring semester of 2018–19 academic year

Student Theses within AUTh

In progress

2017–2018

2016–2017

2015–2016

2014–2015

2013–2014

2012–2013

2010–2011

Book Chapter

Journal Article

Journal Article

Journal Article

Conference Announcement

Journal Article

Conference Announcement

Journal Article

Journal Article

Conference Announcement

Translation

Journal Article

Conference Announcement

Journal Article

Journal Article

Book Chapter

Journal Article

Journal Article

Journal Article

Journal Article

Journal Article

Journal Article

Journal Article

Conference Announcement

Conference Announcement

Conference Announcement

Quality Assurance Unit (MODIP)
Aristotle University of Thessaloniki