Course Content (Syllabus)
Structure of cellular membranes. Transport of water and inorganic ions across membranes, The organization of membrane transport systems – passive transport systems, active transport systems, the γ-glutamyl cycle for amino acid transport, ionophores.
The tricarboxylic acid cycle
Bioenergetics principles and the ATP cycle.The flow sheet of respiration, oxidative respiration, intracellulara location of the enzymes of Krebs cycle, the reactions of Krebs cycle, anaplerotic reactions, regulation of Krebs cycle, the glyoxylate cycle, oxidation-reduction enzymes and electron transport, the respiratory chain, inhibitors of electron transport, proton exchanges during electron transport, microsomal electron transport, superoxide dismutase and catalase , electron transport in other systems.
Sugars, storage polysaccharides and cell walls. Glycoproteins and proteoglycans. Glycose metabolism. The stages of glycolysis. The phosphogluconate pathway. Metabolism of oligo- and polysaccharides, polysaccharide biosynthesis. Photosynthesis. Biosynthesis of mono- and glucose derivatives from glycose. Glycogen biosynthesis and degradation.
The biosynthesis of lipids.Lipoproteins .Lipid metabolism. Biosynthesis of trialcylglycerols, biosynthesis of phosphoglycerides,Genetic disorders in metabolism of the complex lipids, the pathway of cholesterol biosynthesis, biosynthesis of prostagladins.
The biosynthesis of amino acids and some derivatives: Metabolism of inorganic nitrogen.essential and non essential amino acids. Nitrogen fixin organism, enzymic mechanism of nitrogen fixation, other steps in nitrogen cycle.
Vitamins and coenzymes.Water soluble and fat soluble vitamins. Hormones, hormone receptors.