Modelling and Optimisation of Chromatographic Separations
| Title | ΜΟΝΤΕΛΟΠΟΙΗΣΗ ΚΑΙ ΒΕΛΤΙΣΤΟΠΟΙΗΣΗ ΧΡΩΜΑΤΟΓΡΑΦΙΚΩΝ ΔΙΑΧΩΡΙΣΜΩΝ / Modelling and Optimisation of Chromatographic Separations |
| Code | Κ202 |
| Faculty | Sciences |
| School | Chemistry |
| Cycle / Level | 1st / Undergraduate |
| Teaching Period | Spring |
| Common | No |
| Status | Active |
| Course ID | 40002690 |
Programme of Study: PPS-Tmīma CΗīmeías (2016-sīmera)
Registered students: 33
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| THEŌRĪTIKĪ CΗĪMEIA KAI CΗĪMIKĪ EKPAIDEUSĪ | Optional Courses | 8 | 4 | 5 |
| CΗĪMIKĪ ANALYSĪ-PERIVALLON-ĪLEKTROCΗĪMEIA | Elective Course belonging to the selected specialization (Elective Specialization Course) | 8 | 4 | 5 |
| CΗĪMIKĪ SYNTHESĪ-VIOCΗĪMEIA KAI VIOEFARMOGES | Optional Courses | 8 | 4 | 5 |
| CΗĪMIKĪ TECΗNOLOGIA KAI VIOMĪCΗANIKĪ CΗĪMEIA | Optional Courses | 8 | 4 | 5 |
| Academic Year | 2020 – 2021 |
| Class Period | Spring |
| Instructors from Other Categories | |
| Weekly Hours | 6 |
| Class ID | 600171249
|
Course Type 2016-2020
- Background
- Scientific Area
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600171249
- eLearning:
Language of Instruction
- Greek (Instruction, Examination)
Learning Outcomes
Upon successful completion of the course the student is expected to:
- understand the chromatographic separation mechanisms, after acquiring the theoretical background on analytical techniques and physicochemical processes,
- understand how the chromatographic factors are affected (composition of the mobile phase, pH of the mobile phase, flow rate and chromatographic column temperature) in the retention of the compounds and be able to choose the appropriate chromatographic model,
- develop critical thinking on the interpretation and evaluation of chromatographic experimental data,
- to become familiar with the use of Microsoft Excel spreadsheets and appropriate algorithms (macro-commands-VBA) for adapting experimental data, predicting compound retention times and optimizing chromatographic conditions,
- follow the appropriate steps and to apply the fitting, prediction and optimization algorithms, in order to identify the optimal conditions for the separation of the chromatographic peaks of the under analysis mixture.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Make decisions
- Work autonomously
- Advance free, creative and causative thinking
Keywords
Chromatography, Retention prediction, Separation optimization
Educational Material Types
- Slide presentations
- Multimedia
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
- Use of ICT in Student Assessment
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | |||||
| Laboratory Work | |||||
| Reading Assigment | |||||
| Written assigments | |||||
| Exams | |||||
| Total |
Student Assessment
Student Assessment methods
- Written Exam with Short Answer Questions (Formative, Summative)
- Written Exam with Extended Answer Questions (Formative, Summative)
- Written Assignment (Formative, Summative)
- Written Exam with Problem Solving (Formative, Summative)
- Labortatory Assignment (Formative, Summative)
Bibliography
Additional bibliography for study
1.Teaching Simulation and Computer-Aided Separation Optimization in Liquid Chromatography by Means of Illustrative Microsoft Excel Spreadsheets. S. Fasoula, P. Nikitas, and A. Pappa-Louisi. J. Chem. Educ. 94 (2017) 1167−1173.
2.Separation optimization in HPLC analysis implemented in R programming language. Ch.Zisi,A.Pappa-Louisi,P.Nikitas, J. Chrom. A, 1617 (2020) 460823(doi:10.1016/j.chroma.2019.460823)
Last Update
03-07-2020
