Structural Biochemistry and Basics of Biocomputational Chemistry

Course Information
TitleΔΟΜΙΚΗ ΒΙΟΧΗΜΕΙΑ ΚΑΙ ΣΤΟΙΧΕΙΑ ΒΙΟΠΛΗΡΟΦΟΡΙΚΗΣ / Structural Biochemistry and Basics of Biocomputational Chemistry
CodeΚ309
FacultySciences
SchoolChemistry
Cycle / Level1st / Undergraduate
Teaching PeriodSpring
CommonYes
StatusActive
Course ID40002697

Programme of Study: PPS-Tmīma CΗīmeías (2016-sīmera)

Registered students: 0
OrientationAttendance TypeSemesterYearECTS
THEŌRĪTIKĪ CΗĪMEIA KAI CΗĪMIKĪ EKPAIDEUSĪOptional Courses845
CΗĪMIKĪ ANALYSĪ-PERIVALLON-ĪLEKTROCΗĪMEIAOptional Courses845
CΗĪMIKĪ SYNTHESĪ-VIOCΗĪMEIA KAI VIOEFARMOGESElective Course belonging to the selected specialization (Elective Specialization Course)845
CΗĪMIKĪ TECΗNOLOGIA KAI VIOMĪCΗANIKĪ CΗĪMEIAOptional Courses845

Class Information
Academic Year2021 – 2022
Class PeriodSpring
Faculty Instructors
Weekly Hours3
Class ID
600188683
Course Type 2016-2020
  • Scientific Area
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
  • Face to face
Digital Course Content
Language of Instruction
  • Greek (Instruction)
  • English (Instruction)
Prerequisites
Required Courses
  • Υ15 Biochemistry I
  • Υ17 Biochemistry II
Learning Outcomes
Knowledge acquisition regarding searching on scientific Data banks related to proteins and nucleic acids. A deeper study ,based on new technologies, of macromolecular structure (examples of relation to diseases) Introduction to basic tools of bioinformatic .
General Competences
  • Apply knowledge in practice
  • Retrieve, analyse and synthesise data and information, with the use of necessary technologies
  • Adapt to new situations
  • Work in teams
  • Work in an international context
  • Work in an interdisciplinary team
Course Content (Syllabus)
STRUCTURAL BIOCHEMISTRY Basic structural principles, the building blocks, motifs of protein structures, a-domain structures, alpha/beta structures, beta structures, protein folding, DNA structures, helix-turn-helix, DNA recognition by proteins with the helix-turn-helix motif. Structural motifs of eukaryotic transcription factors , structures of serine proteases, structures of membrane proteins, structures of fibrous proteins, recognition of foreign molecules by the immune system, prediction engineering and design of protein structures, determination of protein structures. INTRODUCTION TO BIOINFORMATICS Data base indexing and specification of search terms. Structural bioinformatics. Introduction to sequence alignments, sequence similarity, FASTA, BLAST,multiple alignment, CLUSTALW, MOTIFS, Phylogenetic trees, prediction of secondary structure of proteins and nucleic acids,. Navigation to proteomic and protein engineering tools. Design of primers for PCR. Structural alignment of protein structure.
Keywords
structural Biochemistry, structure function relation ship
Educational Material Types
  • Slide presentations
  • Video lectures
  • Multimedia
  • Interactive excersises
  • Book
Use of Information and Communication Technologies
Use of ICT
  • Use of ICT in Course Teaching
  • Use of ICT in Laboratory Teaching
Description
Video , power point, book
Course Organization
ActivitiesWorkloadECTSIndividualTeamworkErasmus
Lectures261.0
Total261.0
Student Assessment
Student Assessment methods
  • Written Exam with Multiple Choice Questions (Formative)
  • Written Assignment (Formative)
  • Labortatory Assignment (Formative)
Bibliography
Course Bibliography (Eudoxus)
Εισαγωγή στη δομή των πρωτεϊνών( Carl Branden and John Tooze), μεταφραση Βιοπληροφορική (Σοφία Κοσσιδα)
Additional bibliography for study
Bioinformatic ( Sofia Kossida) Introduction to Protein Structure (Carl Branden and John Tooze),translation
Last Update
02-07-2020