Learning Outcomes
Upon successful completion of the course, students will be able to:
a) Understand the basic principles of development in various animal organisms.
b) use of animal models for studying different aspects of developmental and regenerative processes.
c) Understand the principles that govern growth, post-embryonic development, and aging.
d) Understand the principles that govern gametogenesis, fertilization and sex determination.
e) Acquire and apply skills in optical microscopy and stereoscopy for observing, and evaluating different developmental stages of model organisms.
Course Content (Syllabus)
Have you ever wondered how an embryo develops from a simple fertilized egg into a complex multicellular organism? The course "Developmental Biology" explores this question by examining the basic patterns of embryonic development and the mechanisms that control these processes at the cellular and molecular levels. Developmental processes in various animal models are described and studied in the laboratory, such as the nematode, sea urchin, drosophila, birds, zebrafish, mouse, and human. In addition, an introduction is made to the developmental mechanisms that govern post-embryonic development, aging, and regeneration. The Syllabus is based on "Principles of Development" by Wolpert Lewis, Tickle Cheryll, and Arias Martinez Alfonso, with book code on Eudoxus: 86055675, Edition: 1/2020, Publisher: BROKEN HILL PUBLISHERS LTD, ISBN: 9789925575046.
Syllabus:
• INTRODUCTION TO DEVELOPMENTAL BIOLOGY
• EARLY DEVELOPMENT IN DROSOPHILA
• EARLY DEVELOPMENT IN NEMATODES
• EARLY DEVELOPMENT IN SEA URCHINS
• EARLY DEVELOPMENT IN VERTEBRATES
• GAMETIC CELLS, FERTILIZATION, AND SEX DETERMINATION
• MORPHOGENESIS
• GROWTH & POST_EMBRYONIC DEVELOPMENT
• AGING & REGENERATION
LABORATORY EXERCISES.
Stages of embryonic development in the frog and zebrafish; Histological evaluation of normal development in frog embryos; Embryonic and induced pluripotent stem cells; Hematopoietic stem cells; the zebrafish embryo and larvae as an experimental model.