Systems biology
| Title | Βιολογία Συστημάτων / Systems biology |
| Code | ΒΜ01α |
| Faculty | Engineering |
| School | Electrical and Computer Engineering |
| Cycle / Level | 2nd / Postgraduate |
| Teaching Period | Winter |
| Coordinator | Dimosthenis Sarigiannis |
| Common | No |
| Status | Active |
| Course ID | 600020741 |
Programme of Study: DPMS VIOÏATRIKĪ MĪCΗANIKĪ
Registered students: 11
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Compulsory Course | 1 | 1 | 6 |
| Academic Year | 2025 – 2026 |
| Class Period | Winter |
| Faculty Instructors |
|
| Instructors from Other Categories |
|
| Weekly Hours | 4 |
| Class ID | 600289848
|
Course Type 2021
General Foundation
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600289848
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction, Examination)
Prerequisites
General Prerequisites
Basic knowledge of biology and mathematics
Learning Outcomes
Understanding of basic concepts of systems biology
Basic principles of mathematical modeling of biological systems
Understanding models of cellular reactions
Understanding how metabolic networks, metabolic network fluxes and signaling systems are regulated
Understanding basic concepts of gene systems
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Make decisions
- Work autonomously
- Work in an international context
- Work in an interdisciplinary team
- Generate new research ideas
Course Content (Syllabus)
-Biological systems / Biological Systems-Nonlinear Mathematics
-Introduction to mathematical modeling
-Static network models
-The mathematics of biological systems.
-Stability Analysis, phase portraits: Application to population models and SIRS Model Epidemiology
-Chemical Kinetics (Introduction to Peculiar Perturbation Theory)
-Periodic Behavior (Periodic trajectories, Bifurcations, with application to Neurons)
-MDE and Systems Biology (Diffusion reaction MDE, Chemotaxy, Steady states in MDE, traveling waves - with applications in biological models),
-Models of cell reactions
-Estimation of parameters – Parameterization of models
-Gene systems
-Person - Population - Species
-Gene - Structure and regulation
-Genome - Transcriptome - Epigenome
-Polymorphism and Mutations
-New DNA Sequencing and Data Production techniques
-Protein systems
- Metabolic systems
-Structural analysis of metabolic networks Denis
-Dynamic analysis of metabolic network flows Denis
- Signaling systems
-Population systems
-Multidimensional biological analysis – comprehensive analysis of gene expression data, protein and metabolite analysis Denis
-Models based on Spyros physiology
-Systems biology in medicine and drug development
-Systemic biology in personalized prevention
-New horizons in systems biology
oFrom neurons to the brain
oMulti-step models of cancer development
oMultifactorial diseases, inflammation and trauma
oInteraction of environment and health
Keywords
Systems biology, metabolic fluxes, genes, populations, mathematical modeling, cellular reactions, population models
Educational Material Types
- Slide presentations
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
Description
Teaching a lesson using slides
Running a lab with specialized software
Communication with students via email
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 90 | 3.6 | |||
| Laboratory Work | 15 | 0.6 | |||
| Reading Assigment | 15 | 0.6 | |||
| Written assigments | 15 | 0.6 | |||
| Exams | 15 | 0.6 | |||
| Total | 150 | 6 |
Student Assessment
Description
Exam on the curriculum
Written assignment
Student Assessment methods
- Written Exam with Multiple Choice Questions (Summative)
- Written Exam with Short Answer Questions (Summative)
- Written Exam with Extended Answer Questions (Summative)
- Written Assignment (Summative)
Bibliography
Course Bibliography (Eudoxus)
Χορεύοντας στο Ρυθμό της Ζωής - Βιολογική Σχετικότητα-Βιολογία Συστημάτων
Κωδικός Βιβλίου στον Εύδοξο: 112691806
Έκδοση: 1/2024
Συγγραφείς: Noble Denis
ISBN: 9789925350872
Τύπος: Σύγγραμμα
Διαθέτης (Εκδότης): BROKEN HILL PUBLISHERS LTD
Εισαγωγή στη Γονιδιωματική
Κωδικός Βιβλίου στον Εύδοξο: 102124945
Έκδοση: 3η αμερικανική-2η ελληνική/2022
Συγγραφείς: Arthur M. Lesk
ISBN: 9786185173777
Τύπος: Σύγγραμμα
Διαθέτης (Εκδότης): UTOPIA ΕΚΔΟΣΕΙΣ Μ. ΕΠΕ.
Εισαγωγή στη Βιοπληροφορική
Κωδικός Βιβλίου στον Εύδοξο: 94702956
Έκδοση: 5η αμερικανική-1η ελληνική/2021
Συγγραφείς: ARTHUR M. LESK
ISBN: 9786185173616
Τύπος: Σύγγραμμα
Διαθέτης (Εκδότης): UTOPIA ΕΚΔΟΣΕΙΣ Μ. ΕΠΕ
Additional bibliography for study
Systems Biology - The Challenge of Complexity. Shigetada Nakanishi, Ryoichiro Kageyama, Dai Watanabe, Springer Tokyo Berlin Heidelberg New York, ISBN: 978-4-431-87703-5
Last Update
14-02-2024
