Preclinical and Clinical evaluation of drugs
| Title | Προκλινική και κλινική αξιολόγηση φαρμάκων / Preclinical and Clinical evaluation of drugs |
| Code | ΠΜΣΒΦ-Μ3 |
| Faculty | Health Sciences |
| School | Pharmacy |
| Cycle / Level | 2nd / Postgraduate |
| Teaching Period | Winter/Spring |
| Coordinator | Aikaterini Markopoulou |
| Common | No |
| Status | Active |
| Course ID | 600023495 |
Programme of Study: P.M.S. Tmīmatos Farmakeutikīs "Viomīchanikī Farmakeutikī" (2023- )
Registered students: 33
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Compulsory Course | 1 | 1 | 8 |
| Academic Year | 2025 – 2026 |
| Class Period | Winter |
| Faculty Instructors |
|
| Instructors from Other Categories |
|
| Weekly Hours | 45 |
| Total Hours | 585 |
| Class ID | 600281914
|
Course Type 2021
General Foundation
Mode of Delivery
- Face to face
- Distance learning
Digital Course Content
Language of Instruction
- Greek (Instruction, Examination)
- English (Instruction)
Learning Outcomes
The aim of the course is to provide the necessary knowledge on topics related to preclinical and clinical evaluation of pharmaceuticals.
Through this course the postgraduate students will learn to design and evaluate preclinical and clinical study protocols and their results.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Adapt to new situations
- Make decisions
- Work autonomously
- Work in teams
- Generate new research ideas
- Design and manage projects
Course Content (Syllabus)
• Biopharmaceutical. Biopharmaceutical classification system. Determination of biopharmaceutical properties.
• Bioavailability and basic pharmacokinetics.
• Development of new drugs. Pharmacological evaluation and applications. Drug administration and Pharmacogenomic approach.
• Application of population pharmacokinetic models through the Simcyp platform in pharmaceutical research and development of new drugs
• Introduction to Biotechnology.
• Pharmaceutical Biotechnology: Application of protein transduction technology (PTD Technology) to produce recombinant proteins in the context of the therapeutic approach of monogenic - metabolic diseases.
• Bioequivalence studies and IVIVC.
• Dissolution test.
• Antimicrobial chemotherapy drugs. Determination of sensitivity and resistance of microorganisms to antibiotics.
• Pharmacogenomics in the postgenomic era.
• Production of biotechnological drugs on an industrial scale.
Educational Material Types
- Notes
- Slide presentations
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 135 | ||||
| Laboratory Work | 12 | ||||
| Tutorial | 12 | ||||
| Written assigments | 40 | ||||
| Exams | 3 | ||||
| Total | 202 |
Student Assessment
Student Assessment methods
- Written Exam with Multiple Choice Questions (Summative)
- Written Exam with Short Answer Questions (Summative)
- Written Exam with Extended Answer Questions (Summative)
- Written Assignment (Formative)
- Oral Exams (Formative)
- Written Exam with Problem Solving (Summative)
- Labortatory Assignment (Formative)
Last Update
28-02-2024
