Modern Methods in Synthesis and Analysis of Bioactive Compounds and Applications
| Title | ΣΥΓΧΡΟΝΕΣ ΜΕΘΟΔΟΙ ΣΥΝΘΕΣΗΣ ΚΑΙ ΑΝΑΛΥΣΗΣ ΒΙΟΔΡΑΣΤΙΚΩΝ ΕΝΩΣΕΩΝ ΚΑΙ ΕΦΑΡΜΟΓΕΣ / Modern Methods in Synthesis and Analysis of Bioactive Compounds and Applications |
| Code | Ε20 |
| Interdepartmental Programme | Processes and Technology of Advanced Materials |
| Collaborating Schools | Electrical and Computer Engineering Chemical Engineering Mechanical Engineering Chemistry |
| Cycle / Level | 2nd / Postgraduate |
| Teaching Period | Spring |
| Common | No |
| Status | Active |
| Course ID | 600015077 |
Programme of Study: Processes and Technology of Advanced Materials
Registered students: 0
| Orientation | Attendance Type | Semester | Year | ECTS |
|---|---|---|---|---|
| KORMOS | Elective Courses | 2 | 1 | 6.5 |
| Academic Year | 2022 – 2023 |
| Class Period | Spring |
| Faculty Instructors | |
| Weekly Hours | 3 |
| Class ID | 600228318
|
Course Type 2021
Specific Foundation
Course Type 2011-2015
Specific Foundation / Core
Mode of Delivery
- Face to face
Digital Course Content
- e-Study Guide https://qa.auth.gr/en/class/1/600228318
- At the Website of the School: http://dtpy.web.auth.gr/gr/index.html
- eLearning: https://elearning.auth.gr/course/view.php?id=10093
- Other: http://bioinorglab.web.auth.gr/gr_site/metaptyxiaka.htm
Language of Instruction
- Greek (Instruction, Examination)
Prerequisites
General Prerequisites
There are no prerequisite courses to this class
Learning Outcomes
•Have demonstrated knowledge and understanding of subjects in the interdisciplinary domain, which is based on their general university-level training in the courses of materials synthesis, inorganic chemistry, polymer chemistry and, while supported by advanced scientific textbooks, also includes views arising from modern developments in the cutting edge of their interdisciplinary field of knowledge.
•They are able to use the knowledge and understanding they have acquired, in a way that reflects a professional approach to research work and they have abilities that are typically demonstrated by developing and supporting arguments and solving problem approaches within their field of knowledge.
•They have the ability to gather and interpret relevant evidence (usually within the subject area) to formulate judgments that include reflection on relevant social, scientific or ethical issues.
• They have the ability to use spectroscopic and structural techniques of a broad scientific background for the design, synthesis and physicochemical characterization of new compounds with methods of modern technology (nanoscience), further correlating the molecular structure with their biological activity.
•They are able to communicate information, ideas, problems and solutions to both specialist and non-specialist audiences.
• They have developed those knowledge acquisition skills, which they need to continue their studies in an academic and/or industrial setting with a high degree of autonomy.
General Competences
- Apply knowledge in practice
- Retrieve, analyse and synthesise data and information, with the use of necessary technologies
- Make decisions
- Work autonomously
- Work in teams
- Work in an interdisciplinary team
- Generate new research ideas
- Respect natural environment
- Be critical and self-critical
Course Content (Syllabus)
1. Solid phase synthesis (absence of solvent)
2. Preparation of products through a combination of chemical and biochemical processes
3. Analysis of products by LC-MS/MS
4. Study of conformation of macromolecules
5. High resolution NMR spectra (solid and liquid phase spectra)
6. X-ray crystallography
7. FT-IR and Raman spectroscopy
8. Microscopy (SEM-TEM)
9. Structure-function relationship of compounds and their biological activity
10. Encapsulation systems and controlled release of bioactive molecules
Keywords
Synthesis, methodologies, X-rays, microscopy, NMR, Mass spectrometry, encapsulation, FT-IR and Raman, Structure-biological activity relations
Educational Material Types
- Notes
- Slide presentations
- Multimedia
- Book
Use of Information and Communication Technologies
Use of ICT
- Use of ICT in Course Teaching
- Use of ICT in Laboratory Teaching
- Use of ICT in Communication with Students
Description
The use of I.C.T. in live teaching through Power Point presentations (.pptx)
The use of I.C.T. in conducting workshops
The use of I.C.T. in communication with students
Course Organization
| Activities | Workload | ECTS | Individual | Teamwork | Erasmus |
|---|---|---|---|---|---|
| Lectures | 39 | 1.6 | ✓ | ||
| Laboratory Work | 24 | 1.0 | ✓ | ✓ | |
| Reading Assigment | 49.5 | 2.0 | ✓ | ||
| Tutorial | 21 | 0.8 | |||
| Written assigments | 26 | 1.0 | ✓ | ||
| Exams | 3 | 0.1 | ✓ | ||
| Total | 162.5 | 6.5 |
Student Assessment
Description
Description of Procedure:
The student evaluation criteria can be found on the website: http://dtpy.web.auth.gr/gr/index.html
Evaluation Methods:
1. Written Examination with Extended Response Questions (Formative, Conclusive)
2. Laboratory Work (Formative, Conclusive)
3. Other / Others (Formative, Conclusive)
Student Assessment methods
- Written Exam with Extended Answer Questions (Formative, Summative)
- Clinical Examination of Patient (Formative, Summative)
Bibliography
Course Bibliography (Eudoxus)
Η βιβλιογραφία σχετίζεται με τις διδασκόμενες τεχνικές και προσεγγίσεις σε θεωρητικό και πειραματικό επίπεδο. Αυτή δίνεται παρακάτω:
1. Experimental Methods in the Physical Sciences
Book Series, Elsevier
2. Physical Methods in Bioinorganic Chemistry
by Lawrence Que
University Science Books, 2000
3. Solvent-free Organic Synthesis, 2006
Koichi Tanaka ISBN: 978-3-527-60536-1
4. NMR Spectroscopy explained, (simplified theory, applications and examples for organic chemistry and structural Biology) Neil E. Jacobsen, Ph.D. University of Arizona, Wiley Interscience, 2007, ISBN 978-0-471-73096-5
5. LC/MS : a practical user’s guide
McMaster, Marvin C.
Hoboken, N.J.: Wiley-Interscience, c2005
ISBN: 0471655317 (cloth)
6. Physical Methods in Heterocyclic Chemistry
A Comprehensive Treatise in Six Volumes, Volume III, 1973
Edited by:A. Katritzky
7. Introduction to Experimental Biophysics: Biological Methods for Physical Scientists
Jay Nadeau, 2011 by CRC Press
8. Methods for Investigation of Amino Acid and Protein Metabolism
Antoine E. El-Khoury, 1999 by CRC Press
9. Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery Corrado Tringali, 2011 by CRC Press
Additional bibliography for study
The literature is linked to the taught techniques and approaches and is provided at a theoretical and experimental level below:
1. Experimental Methods in the Physical Sciences
Book Series, Elsevier
2. Physical Methods in Bioinorganic Chemistry
by Lawrence Que
University Science Books, 2000
3. Solvent-free Organic Synthesis, 2006
Koichi Tanaka ISBN: 978-3-527-60536-1
4. NMR Spectroscopy explained, (simplified theory, applications and examples for organic chemistry and structural Biology) Neil E. Jacobsen, Ph.D. University of Arizona, Wiley Interscience, 2007, ISBN 978-0-471-73096-5
5. LC/MS : a practical user’s guide
McMaster, Marvin C.
Hoboken, N.J.: Wiley-Interscience, c2005
ISBN: 0471655317 (cloth)
6. Physical Methods in Heterocyclic Chemistry
A Comprehensive Treatise in Six Volumes, Volume III, 1973
Edited by:A. Katritzky
7. Introduction to Experimental Biophysics: Biological Methods for Physical Scientists
Jay Nadeau, 2011 by CRC Press
8. Methods for Investigation of Amino Acid and Protein Metabolism
Antoine E. El-Khoury, 1999 by CRC Press
9. Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery Corrado Tringali, 2011 by CRC Press
Last Update
15-03-2024
